Structural Classification of Proteins

Superfamily: Thiamin diphosphate-binding fold (THDP-binding)

: there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
uperfamily

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: Thiamin diphosphate-binding fold (THDP-binding) [52517]
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
Superfamily: Thiamin diphosphate-binding fold (THDP-binding) [52518]
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
uperfamily

Families:

Pyruvate oxidase and decarboxylase Pyr module [88724] (12)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
1. Pyruvate decarboxylase [88725]
  1. Brewer's yeast (Saccharomyces), uvarum strain [TaxId: 4932] [88726] (1)
    1. 1pyd
      complexed with mg, tdp
      1. region a:2-181 [31773]
      2. region b:2-181 [31775]
  2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88727] (2)
    1. 1pvd
      complexed with mg, tpp
      1. region a:2-181 [31777]
      2. region b:2-181 [31779]
    2. 1qpb
      1. region a:2-181 [31781]
      2. region b:2-181 [31783]
  3. Zymomonas mobilis [TaxId: 542] [88728] (1)
    1. 1zpd
      complexed with cit, dpx, mg
      1. region a:2-187 [31785]
      2. region b:2-187 [31787]
      3. region e:2-187 [31789]
      4. region f:2-187 [31791]
2. Indole-3-pyruvate decarboxylase [89648]
  1. Enterobacter cloacae [TaxId: 550] [89649] (1)
    1. 1ovm
      complexed with mg, tpp
      1. region a:3-180 [87462]
      2. region b:3-180 [87465]
      3. region c:3-180 [87468]
      4. region d:3-180 [87471]
3. Pyruvate oxidase [88729]
  1. Lactobacillus plantarum [TaxId: 1590] [88730] (12)
    1. 2ez9
      automatically matched to d1powa2
      complexed with fad, mg, na, tdk; mutant
      1. region a:9-182 [132628]
    2. 2ez9
      automatically matched to d1powa2
      complexed with fad, mg, na, tdk; mutant
      1. region b:9-182 [132631]
    3. 2ez8
      automatically matched to d1powa2
      complexed with fad, mg, na, pyr, tdl; mutant
      1. region a:9-182 [132622]
    4. 2ez8
      automatically matched to d1powa2
      complexed with fad, mg, na, pyr, tdl; mutant
      1. region b:9-182 [132625]
    5. 2ez4
      automatically matched to d1powa2
      complexed with fad, mg, na, po4, tpp; mutant
      1. region a:9-182 [132611]
    6. 2ez4
      automatically matched to d1powa2
      complexed with fad, mg, na, po4, tpp; mutant
      1. region b:9-182 [132614]
    7. 2ezu
      automatically matched to d1powa2
      complexed with fad, htl, mg, na, pyr; mutant
      1. region a:9-182 [132640]
    8. 2ezu
      automatically matched to d1powa2
      complexed with fad, htl, mg, na, pyr; mutant
      1. region b:9-182 [132643]
    9. 1pox
      complexed with fad, gol, mg, na, tpp; mutant
      1. region a:9-182 [31793]
      2. region b:9-182 [31795]
    10. 2ezt
      automatically matched to d1powa2
      complexed with fad, mg, na, po4, pyr, tdm; mutant
      1. region a:9-182 [132634]
    11. 2ezt
      automatically matched to d1powa2
      complexed with fad, mg, na, po4, pyr, tdm; mutant
      1. region b:9-182 [132637]
    12. 1pow
      complexed with fad, mg, tpp
      1. region a:9-182 [31797]
      2. region b:9-182 [31799]
  2. Aerococcus viridans [TaxId: 1377] [142203] (4)
    1. 2dji
      automatically matched to 1V5E A:3-186
      complexed with fad, so4
      1. region a:3-186 [131545]
    2. 1v5e
      complexed with fad, so4
      1. region a:3-186 [119845]
    3. 1v5f
      automatically matched to 1V5E A:3-186
      complexed with fad, mg, so4, tpp
      1. region a:4-186 [119848]
    4. 1v5g
      automatically matched to 1V5E A:3-186
      complexed with fad, htl, mg
      1. region a:4-186 [119851]
4. Benzoylformate decarboxylase [88731]
  1. Pseudomonas putida [TaxId: 303] [88732] (12)
    SQ P20906
    1. 1q6z
      complexed with ca, mg, tdp; mutant
      1. region a:2-181 [111656]
    2. 2fn3
      automatically matched to d1bfd_2
      complexed with ca, mg, tzd; mutant
      1. region a:2-181 [133804]
    3. 1pi3
      complexed with ca, mg, tdp; mutant
      1. region a:2-181 [111634]
    4. 1po7
      complexed with ca, mg, tdp; mutant
      1. region a:2-181 [111637]
    5. 1yno
      automatically matched to d1bfd_2
      complexed with ca, mg, tzd
      1. region a:2-181 [123748]
    6. 2fwn
      automatically matched to d1bfd_2
      complexed with ca, mg, tdp
      1. region a:2-181 [134250]
    7. 1bfd
      complexed with ca, mg, tpp
      1. region a:2-181 [31801]
    8. 2v3w
      automatically matched to d1bfda2
      complexed with mg, so4, tpp; mutant
      1. region a:2-181 [152466]
    9. 2v3w
      automatically matched to d1bfda2
      complexed with mg, so4, tpp; mutant
      1. region b:2-181 [152469]
    10. 2v3w
      automatically matched to d1bfda2
      complexed with mg, so4, tpp; mutant
      1. region c:2-181 [152472]
    11. 2v3w
      automatically matched to d1bfda2
      complexed with mg, so4, tpp; mutant
      1. region d:2-181 [152475]
    12. 1mcz
      complexed with mg, rmn, tdp
      1. region a:2-181 [78953]
      2. region b:2-181 [78956]
      3. region c:2-181 [78959]
      4. region d:2-181 [78962]
      5. region e:2-181 [78965]
      6. region f:2-181 [78968]
      7. region g:2-181 [78971]
      8. region h:2-181 [78974]
      9. region i:2-181 [78977]
      10. region j:2-181 [78980]
      11. region k:2-181 [78983]
      12. region l:2-181 [78986]
      13. region m:2-181 [78989]
      14. region n:2-181 [78992]
      15. region o:2-181 [78995]
      16. region p:2-181 [78998]
5. Acetohydroxyacid synthase catalytic subunit [88733]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88734] (6)
    SQ P07342 84-687
    1. 1t9b
      complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
      1. region a:89-263 [112335]
      2. region b:89-263 [112338]
    2. 1t9c
      complexed with 1sm, fad, k, mg, p22, p23
      1. region a:89-263 [112341]
      2. region b:89-263 [112344]
    3. 1t9d
      complexed with 1mm, fad, k, mg, p22, p25, yf1
      1. region a:89-263 [112347]
      2. region b:89-263 [112350]
      3. region c:89-263 [112353]
      4. region d:89-263 [112356]
    4. 1t9a
      complexed with 1tb, fad, k, mg, p23, yf3, yf4
      1. region a:89-263 [112329]
      2. region b:89-263 [112332]
    5. 1jsc
      complexed with 2hp, fad, k, mg, tpp
      1. region a:83-270 [67225]
      2. region b:82-272 [67228]
    6. 1n0h
      complexed with ayd, cie, dtt, fad, k, mg, tpp
      1. region a:83-270 [79735]
      2. region b:83-270 [79738]
  2. Thale cress (Arabidopsis thaliana), chloroplast [TaxId: 3702] [142204] (6)
    SQ P17597 86-280
    1. 1ybh
      complexed with cie, fad, mg, nhe, p22
      1. region a:86-280 [122892]
    2. 1yi0
      automatically matched to 1YBH A:86-280
      complexed with 1sm, fad, mg, nhe, p22
      1. region a:86-280 [123222]
    3. 1yhz
      automatically matched to 1YBH A:86-280
      complexed with 1cs, fad, mg, nhe, p22
      1. region a:86-280 [123219]
    4. 1yhy
      automatically matched to 1YBH A:86-280
      complexed with 1mm, fad, mg, nhe, p22
      1. region a:86-280 [123216]
    5. 1yi1
      automatically matched to 1YBH A:86-280
      complexed with 1tb, fad, mg, nhe, p22
      1. region a:86-280 [123225]
    6. 1z8n
      automatically matched to 1YBH A:86-280
      complexed with 1iq, fad, mg, nhe, tpp
      1. region a:86-280 [124720]
6. Catabolic acetolactate synthase [102328]
  1. Klebsiella pneumoniae [TaxId: 573] [102329] (3)
    1. 1ozh
      complexed with he3, mg, peg, pig, po4
      1. region a:7-187 [93834]
      2. region b:7-187 [93837]
      3. region c:7-186 [93840]
      4. region d:7-187 [93843]
    2. 1ozf
      complexed with mg, peg, po4, tpp
      1. region a:7-187 [93822]
      2. region b:5-187 [93825]
    3. 1ozg
      complexed with he3, mg, peg, po4
      1. region a:6-187 [93828]
      2. region b:5-187 [93831]
7. Carboxyethylarginine synthase [102330]
  1. Streptomyces clavuligerus [TaxId: 1901] [102331] (11)
    1. 2iht
      automatically matched to d1upaa2
      complexed with gol, mg, so4, tpp
      1. region a:12-197 [147686]
    2. 2iht
      automatically matched to d1upaa2
      complexed with gol, mg, so4, tpp
      1. region b:12-197 [147689]
    3. 2iht
      automatically matched to d1upaa2
      complexed with gol, mg, so4, tpp
      1. region c:12-197 [147692]
    4. 2iht
      automatically matched to d1upaa2
      complexed with gol, mg, so4, tpp
      1. region d:12-197 [147695]
    5. 2ihu
      automatically matched to d1upaa2
      complexed with gol, k, mg, tar, tp8, tp9
      1. region a:12-197 [147698]
    6. 2ihv
      automatically matched to d1upaa2
      complexed with gva, k, mg, tpp
      1. region a:12-197 [147701]
    7. 2ihv
      automatically matched to d1upaa2
      complexed with gva, k, mg, tpp
      1. region b:12-197 [147704]
    8. 2ihv
      automatically matched to d1upaa2
      complexed with gva, k, mg, tpp
      1. region d:12-197 [147707]
    9. 1upa
      complexed with mg, so4, tpp
      1. region a:12-197 [99715]
      2. region b:12-197 [99718]
      3. region c:12-197 [99721]
      4. region d:12-197 [99724]
    10. 1upb
      complexed with mg, so4, tpp
      1. region a:12-197 [99727]
      2. region b:12-197 [99730]
      3. region c:12-197 [99733]
      4. region d:12-197 [99736]
    11. 1upc
      complexed with mg, so4, tpp
      1. region a:12-197 [99739]
      2. region b:12-197 [99742]
      3. region c:12-197 [99745]
      4. region d:12-197 [99748]
      5. region e:12-197 [99751]
      6. region f:12-197 [99754]
8. Oxalyl-CoA decarboxylase [142205]
  1. Oxalobacter formigenes [TaxId: 847] [142206] (12)
    SQ P40149 7-194
    1. 2ji7
      automatically matched to d2c31a2
      complexed with adp, b3p, mg, oxt, pge
      1. region a:7-194 [148063]
    2. 2ji7
      automatically matched to d2c31a2
      complexed with adp, b3p, mg, oxt, pge
      1. region b:7-194 [148066]
    3. 2c31
      complexed with adp, mg, tzd
      1. region a:7-194 [129705]
    4. 2c31
      automatically matched to 2C31 A:7-194
      complexed with adp, mg, tzd
      1. region b:7-194 [129708]
    5. 2ji6
      automatically matched to d2c31a2
      complexed with adp, b3p, mg, oxk, pge, tpw
      1. region a:7-194 [148057]
    6. 2ji6
      automatically matched to d2c31a2
      complexed with adp, b3p, mg, oxk, pge, tpw
      1. region b:7-194 [148060]
    7. 2ji9
      automatically matched to d2c31a2
      complexed with adp, b3p, mg, tpw
      1. region a:7-194 [148075]
    8. 2ji9
      automatically matched to d2c31a2
      complexed with adp, b3p, mg, tpw
      1. region b:7-194 [148078]
    9. 2ji8
      automatically matched to d2c31a2
      complexed with adp, fyn, mg, pge, tpp
      1. region a:7-194 [148069]
    10. 2ji8
      automatically matched to d2c31a2
      complexed with adp, fyn, mg, pge, tpp
      1. region b:7-194 [148072]
    11. 2jib
      automatically matched to d2c31a2
      complexed with adp, coa, mg, pge, tpp
      1. region a:7-194 [148081]
    12. 2jib
      automatically matched to d2c31a2
      complexed with adp, coa, mg, pge, tpp
      1. region b:7-194 [148084]
TK-like Pyr module [88735] (5)
different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
1. Transketolase (TK), Pyr module [88736]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88737] (7)
    1. 1gpu
      complexed with ca, thd
      1. region a:338-534 [65455]
      2. region b:338-534 [65458]
    2. 1trk
      complexed with ca, tpp
      1. region a:338-534 [31804]
      2. region b:338-534 [31806]
    3. 1tkb
      complexed with ca, n1t
      1. region a:338-534 [31808]
      2. region b:338-534 [31810]
    4. 1tkc
      complexed with ca, m6t
      1. region a:338-534 [31812]
      2. region b:338-534 [31814]
    5. 1ngs
      complexed with ca, e4p, tpp
      1. region a:338-534 [31820]
      2. region b:338-534 [31822]
    6. 1tka
      complexed with ca, n3t
      1. region a:338-534 [31816]
      2. region b:338-534 [31818]
    7. 1ay0
      complexed with ca, tpp; mutant
      1. region a:338-534 [31824]
      2. region b:338-534 [31826]
  2. Maize (Zea mays) [TaxId: 4577] [88738] (1)
    1. 1itz
      complexed with mg, tpp
      1. region a:348-539 [76798]
      2. region b:348-539 [76801]
      3. region c:348-539 [76804]
  3. Escherichia coli [TaxId: 562] [89650] (7)
    1. 2r8o
      automatically matched to d1qgda1
      complexed with ca, edo, t5x
      1. region a:333-527 [151731]
    2. 2r8o
      automatically matched to d1qgda1
      complexed with ca, edo, t5x
      1. region b:333-527 [151734]
    3. 2r5n
      automatically matched to d1qgda1
      complexed with ca, edo, r5p, rp5, tpp
      1. region a:333-527 [151591]
    4. 2r5n
      automatically matched to d1qgda1
      complexed with ca, edo, r5p, rp5, tpp
      1. region b:333-527 [151594]
    5. 2r8p
      automatically matched to d1qgda1
      complexed with ca, edo, t6f
      1. region a:333-527 [151737]
    6. 2r8p
      automatically matched to d1qgda1
      complexed with ca, edo, t6f
      1. region b:333-527 [151740]
    7. 1qgd
      complexed with ca, so4, tpp
      1. region a:333-527 [88367]
      2. region b:333-527 [88370]
  4. Leishmania mexicana mexicana [TaxId: 44270] [117521] (1)
    SQ Q8MPM3
    1. 1r9j
      complexed with ca, tpp
      1. region a:337-526 [111722]
      2. region b:337-526 [111725]
2. Pyruvate dehydrogenase E1 component, Pyr module [88739]
  E1A and E1B fused together in a single-chain protein
  1. Escherichia coli [TaxId: 562] [88740] (14)
    1. 2iea
      automatically matched to d1l8aa2
      complexed with mg, tdp
      1. region a:471-700 [137294]
    2. 2iea
      automatically matched to d1l8aa2
      complexed with mg, tdp
      1. region b:471-700 [137297]
    3. 2qta
      automatically matched to d1l8aa2
      complexed with mg, tdp; mutant
      1. region a:471-700 [151333]
    4. 2qta
      automatically matched to d1l8aa2
      complexed with mg, tdp; mutant
      1. region b:471-700 [151336]
    5. 2qtc
      automatically matched to d1l8aa2
      complexed with mg, tdk; mutant
      1. region a:471-700 [151343]
    6. 2qtc
      automatically matched to d1l8aa2
      complexed with mg, tdk; mutant
      1. region b:471-700 [151346]
    7. 1l8a
      complexed with mg, tdp
      1. region a:471-700 [73678]
      2. region b:471-700 [73681]
    8. 2g28
      automatically matched to d1l8aa2
      complexed with mg, tdk
      1. region a:471-700 [134529]
    9. 2g28
      automatically matched to d1l8aa2
      complexed with mg, tdk
      1. region b:471-700 [134532]
    10. 2g25
      automatically matched to d1l8aa2
      complexed with mg, po4, tdk
      1. region a:471-700 [134523]
    11. 2g25
      automatically matched to d1l8aa2
      complexed with mg, po4, tdk
      1. region b:471-700 [134526]
    12. 1rp7
      complexed with mg, tzd
      1. region a:471-700 [97702]
      2. region b:471-700 [97705]
    13. 2g67
      automatically matched to d1l8aa2
      1. region a:471-700 [134695]
    14. 2g67
      automatically matched to d1l8aa2
      1. region b:471-700 [134698]
Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (6)
parent family to TK and PFOR
heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
1. Branched-chain alpha-keto acid dehydrogenase, Pyr module [88742]
  1. Human (Homo sapiens) [TaxId: 9606] [88743] (21)
    SQ P21953 52-392
    1. 2bfd
      automatically matched to d1olsb1
      complexed with cl, gol, k, mn, mpd, tdp; mutant
      1. region b:2-204 [128419]
    2. 2bff
      automatically matched to d1olsb1
      complexed with gol, k, mn, tzd
      1. region b:2-204 [128421]
    3. 1x7y
      complexed with cl, gol, k, mn, tdp; mutant
      1. region b:14-204 [114945]
    4. 2bfc
      automatically matched to d1olsb1
      complexed with gol, k, mn, tzd; mutant
      1. region b:2-204 [128417]
    5. 1x7z
      complexed with cl, gol, k, mn, tdp; mutant
      1. region b:14-204 [114948]
    6. 1x7w
      complexed with cl, gol, k, mn, tdp; mutant
      1. region b:14-204 [114939]
    7. 2bev
      automatically matched to d1olsb1
      complexed with cl, gol, k, mn, thy
      1. region b:2-204 [128393]
    8. 2bew
      automatically matched to d1olsb1
      complexed with cl, gol, k, mn, thw
      1. region b:2-204 [128396]
    9. 1v16
      complexed with bdn, cl, gol, k, mn, tdp; mutant
      1. region b:2-204 [108241]
    10. 1wci
      automatically matched to d1olsb1
      complexed with cl, gol, k, mn, wwf
      1. region b:2-204 [120891]
    11. 1u5b
      complexed with gol, k, mn, tdp
      1. region b:14-204 [113035]
    12. 1v1r
      complexed with cl, gol, k, na, so4
      1. region b:2-204 [108273]
    13. 1olu
      complexed with gol, k, mg, tdp; mutant
      1. region b:2-204 [93336]
    14. 1v11
      complexed with bdn, cl, gol, k, mn, tdp; mutant
      1. region b:2-204 [108228]
    15. 1ols
      complexed with gol, k, mn, tdp
      1. region b:2-204 [93332]
    16. 1v1m
      complexed with bdn, cl, gol, k, mn, tdp; mutant
      1. region b:2-204 [108262]
    17. 2beu
      automatically matched to d1olsb1
      complexed with cl, gol, k, mn, so4, thv
      1. region b:2-204 [128390]
    18. 1x80
      complexed with cl, gol, k, mn, tdp
      1. region b:14-204 [114951]
    19. 1x7x
      complexed with cl, gol, k, mn, tdp; mutant
      1. region b:14-204 [114942]
    20. 1olx
      complexed with gol, k, mn, tdp; mutant
      1. region b:2-204 [93339]
    21. 1dtw
      complexed with k, mg, tdp
      1. region b:17-204 [31828]
  2. Thermus thermophilus [TaxId: 274] [102332] (4)
    1. 1umd
      complexed with coi, mg, tdp
      1. region b:2-187 [99600]
      2. region d:2-187 [99603]
    2. 1umb
      complexed with mg, tdp
      1. region b:2-187 [99588]
      2. region d:2-187 [99591]
    3. 1um9
      complexed with so4
      1. region b:2-187 [99582]
      2. region d:2-187 [99585]
    4. 1umc
      complexed with 4mv, mg, tdp
      1. region b:2-187 [99594]
      2. region d:2-187 [99597]
2. 2-oxoisovalerate dehydrogenase (E1B), Pyr module [88744]
  chain A is alpha-subunit and chain B is beta-subunit
  1. Pseudomonas putida [TaxId: 303] [88745] (5)
    1. 1qs0
      complexed with hri, mg, tdp
      1. region b:2-205 [31830]
    2. 2bp7
      automatically matched to d1qs0b1
      1. region b:2-205 [128927]
    3. 2bp7
      automatically matched to d1qs0b1
      1. region d:2-205 [128930]
    4. 2bp7
      automatically matched to d1qs0b1
      1. region f:2-205 [128933]
    5. 2bp7
      automatically matched to d1qs0b1
      1. region h:2-205 [128936]
3. E1-beta subunit of pyruvate dehydrogenase, Pyr module [69472]
  1. Archaeon Pyrobaculum aerophilum [TaxId: 13773] [69473] (1)
    1. 1ik6
      structure determined on its own rather in the complex with E1-alpha
      1. region a:1-191 [66174]
  2. Human (Homo sapiens) [TaxId: 9606] [89653] (3)
    1. 2ozl
      automatically matched to d1ni4b1
      complexed with k, mg, tpp; mutant
      1. region b:0-191 [139447]
    2. 2ozl
      automatically matched to d1ni4b1
      complexed with k, mg, tpp; mutant
      1. region d:0-191 [139449]
    3. 1ni4
      complexed with k, mg, mse, tpp; mutant
      1. region b:0-191 [85729]
      2. region d:0-191 [85732]
4. Pyruvate dehydrogenase E1-beta, PdhB, N-terminal domain [117522]
  1. Bacillus stearothermophilus [TaxId: 1422] [117523] (2)
    SQ P21874
    1. 1w85
      complexed with k, mg, peg, tdp
      1. region b:1-192 [114336]
      2. region d:1-192 [114339]
      3. region f:1-192 [114342]
      4. region h:1-192 [114345]
    2. 1w88
      complexed with mg, tdp; mutant
      1. region b:1-192 [114350]
      2. region d:1-192 [114353]
      3. region f:1-192 [114356]
      4. region h:1-192 [114359]
PFOR Pyr module [88746] (1)
domains VI, I and II are arranged in the same way as the TK PP, Pyr and C domains
1. Pyruvate-ferredoxin oxidoreductase, PFOR, domain I [88747]
  1. Desulfovibrio africanus [TaxId: 873] [88748] (17)
    1. 2c42
      automatically matched to d1b0pa1
      complexed with ca, mg, pyr, sf4, tpp
      1. region a:2-258 [129790]
    2. 2c42
      automatically matched to d1b0pa1
      complexed with ca, mg, pyr, sf4, tpp
      1. region b:2-258 [129795]
    3. 2c3m
      automatically matched to d1b0pa1
      complexed with ca, cl, mg, sf4, tpp
      1. region a:2-258 [129740]
    4. 2c3m
      automatically matched to d1b0pa1
      complexed with ca, cl, mg, sf4, tpp
      1. region b:2-258 [129745]
    5. 2c3y
      automatically matched to d1b0pa1
      complexed with ca, co2, htl, mg, sf4
      1. region a:2-258 [129780]
    6. 2c3y
      automatically matched to d1b0pa1
      complexed with ca, co2, htl, mg, sf4
      1. region b:2-258 [129785]
    7. 1kek
      complexed with ca, co2, fs4, htl, mg
      1. region a:2-258 [68524]
      2. region b:2-258 [68529]
    8. 2c3p
      automatically matched to d1b0pa1
      complexed with 1tp, ca, mg, sf4
      1. region a:2-258 [129760]
    9. 2c3p
      automatically matched to d1b0pa1
      complexed with 1tp, ca, mg, sf4
      1. region b:2-258 [129765]
    10. 2uza
      automatically matched to d1b0pa1
      complexed with ca, co2, htl, mg, sf4
      1. region a:2-258 [152325]
    11. 2uza
      automatically matched to d1b0pa1
      complexed with ca, co2, htl, mg, sf4
      1. region b:2-258 [152330]
    12. 2c3u
      automatically matched to d1b0pa1
      complexed with 2tp, ca, mg, pyr, sf4
      1. region a:2-258 [129770]
    13. 2c3u
      automatically matched to d1b0pa1
      complexed with 2tp, ca, mg, pyr, sf4
      1. region b:2-258 [129775]
    14. 1b0p
      complexed with ca, fs4, mg, tpp
      1. region a:2-258 [31831]
      2. region b:2-258 [31833]
    15. 2c3o
      automatically matched to d1b0pa1
      complexed with ca, mg, pyr, sf4, tpp
      1. region a:2-258 [129750]
    16. 2c3o
      automatically matched to d1b0pa1
      complexed with ca, mg, pyr, sf4, tpp
      1. region b:2-258 [129755]
    17. 2pda
      complexed with ca, fs4, mg, pyr, tpp
      1. region a:2-258 [31835]
      2. region b:2-258 [31837]
Pyruvate oxidase and decarboxylase PP module [88749] (12)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
1. Pyruvate decarboxylase [88750]
  1. Brewer's yeast (Saccharomyces), uvarum strain [TaxId: 4932] [88751] (1)
    1. 1pyd
      complexed with mg, tdp
      1. region a:361-556 [31774]
      2. region b:361-556 [31776]
  2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88752] (2)
    1. 1pvd
      complexed with mg, tpp
      1. region a:361-556 [31778]
      2. region b:361-556 [31780]
    2. 1qpb
      1. region a:361-556 [31782]
      2. region b:361-556 [31784]
  3. Zymomonas mobilis [TaxId: 542] [88753] (1)
    1. 1zpd
      complexed with cit, dpx, mg
      1. region a:363-566 [31786]
      2. region b:363-566 [31788]
      3. region e:363-566 [31790]
      4. region f:363-566 [31792]
2. Indole-3-pyruvate decarboxylase [89654]
  1. Enterobacter cloacae [TaxId: 550] [89655] (1)
    1. 1ovm
      complexed with mg, tpp
      1. region a:356-551 [87463]
      2. region b:356-551 [87466]
      3. region c:356-551 [87469]
      4. region d:356-551 [87472]
3. Pyruvate oxidase [88754]
  1. Lactobacillus plantarum [TaxId: 1590] [88755] (12)
    1. 2ez9
      automatically matched to d1powa3
      complexed with fad, mg, na, tdk; mutant
      1. region a:366-593 [132629]
    2. 2ez9
      automatically matched to d1powa3
      complexed with fad, mg, na, tdk; mutant
      1. region b:366-593 [132632]
    3. 2ez8
      automatically matched to d1powa3
      complexed with fad, mg, na, pyr, tdl; mutant
      1. region a:366-593 [132623]
    4. 2ez8
      automatically matched to d1powa3
      complexed with fad, mg, na, pyr, tdl; mutant
      1. region b:366-593 [132626]
    5. 2ez4
      automatically matched to d1powa3
      complexed with fad, mg, na, po4, tpp; mutant
      1. region a:366-593 [132612]
    6. 2ez4
      automatically matched to d1powa3
      complexed with fad, mg, na, po4, tpp; mutant
      1. region b:366-593 [132615]
    7. 2ezu
      automatically matched to d1powa3
      complexed with fad, htl, mg, na, pyr; mutant
      1. region a:366-593 [132641]
    8. 2ezu
      automatically matched to d1powa3
      complexed with fad, htl, mg, na, pyr; mutant
      1. region b:366-593 [132644]
    9. 1pox
      complexed with fad, gol, mg, na, tpp; mutant
      1. region a:366-593 [31794]
      2. region b:366-593 [31796]
    10. 2ezt
      automatically matched to d1powa3
      complexed with fad, mg, na, po4, pyr, tdm; mutant
      1. region a:366-593 [132635]
    11. 2ezt
      automatically matched to d1powa3
      complexed with fad, mg, na, po4, pyr, tdm; mutant
      1. region b:366-593 [132638]
    12. 1pow
      complexed with fad, mg, tpp
      1. region a:366-593 [31798]
      2. region b:366-593 [31800]
  2. Aerococcus viridans [TaxId: 1377] [142207] (4)
    1. 2dji
      automatically matched to 1V5E A:364-592
      complexed with fad, so4
      1. region a:364-592 [131546]
    2. 1v5e
      complexed with fad, so4
      1. region a:364-592 [119846]
    3. 1v5f
      automatically matched to 1V5E A:364-592
      complexed with fad, mg, so4, tpp
      1. region a:364-592 [119849]
    4. 1v5g
      automatically matched to 1V5E A:364-592
      complexed with fad, htl, mg
      1. region a:364-592 [119852]
4. Benzoylformate decarboxylase [88756]
  1. Pseudomonas putida [TaxId: 303] [88757] (12)
    SQ P20906
    1. 1q6z
      complexed with ca, mg, tdp; mutant
      1. region a:342-524 [111657]
    2. 2fn3
      automatically matched to d1mcza3
      complexed with ca, mg, tzd; mutant
      1. region a:342-525 [133805]
    3. 1pi3
      complexed with ca, mg, tdp; mutant
      1. region a:342-524 [111635]
    4. 1po7
      complexed with ca, mg, tdp; mutant
      1. region a:342-524 [111638]
    5. 1yno
      automatically matched to d1mcza3
      complexed with ca, mg, tzd
      1. region a:342-525 [123749]
    6. 2fwn
      automatically matched to d1mcza3
      complexed with ca, mg, tdp
      1. region a:342-525 [134251]
    7. 1bfd
      complexed with ca, mg, tpp
      1. region a:342-524 [31802]
    8. 2v3w
      automatically matched to d1mcza3
      complexed with mg, so4, tpp; mutant
      1. region a:342-525 [152467]
    9. 2v3w
      automatically matched to d1mcza3
      complexed with mg, so4, tpp; mutant
      1. region b:342-525 [152470]
    10. 2v3w
      automatically matched to d1mcza3
      complexed with mg, so4, tpp; mutant
      1. region c:342-525 [152473]
    11. 2v3w
      automatically matched to d1mcza3
      complexed with mg, so4, tpp; mutant
      1. region d:342-525 [152476]
    12. 1mcz
      complexed with mg, rmn, tdp
      1. region a:342-525 [78954]
      2. region b:342-525 [78957]
      3. region c:342-525 [78960]
      4. region d:342-525 [78963]
      5. region e:342-525 [78966]
      6. region f:342-525 [78969]
      7. region g:342-525 [78972]
      8. region h:342-525 [78975]
      9. region i:342-525 [78978]
      10. region j:342-525 [78981]
      11. region k:342-525 [78984]
      12. region l:342-525 [78987]
      13. region m:342-525 [78990]
      14. region n:342-525 [78993]
      15. region o:342-525 [78996]
      16. region p:342-525 [78999]
5. Acetohydroxyacid synthase catalytic subunit [88758]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88759] (6)
    SQ P07342 84-687
    1. 1t9b
      complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
      1. region a:461-687 [112336]
      2. region b:461-687 [112339]
    2. 1t9c
      complexed with 1sm, fad, k, mg, p22, p23
      1. region a:461-687 [112342]
      2. region b:461-687 [112345]
    3. 1t9d
      complexed with 1mm, fad, k, mg, p22, p25, yf1
      1. region a:461-687 [112348]
      2. region b:461-687 [112351]
      3. region c:461-687 [112354]
      4. region d:461-687 [112357]
    4. 1t9a
      complexed with 1tb, fad, k, mg, p23, yf3, yf4
      1. region a:461-687 [112330]
      2. region b:461-687 [112333]
    5. 1jsc
      complexed with 2hp, fad, k, mg, tpp
      1. region a:461-648 [67226]
      2. region b:464-649 [67229]
    6. 1n0h
      complexed with ayd, cie, dtt, fad, k, mg, tpp
      1. region a:461-687 [79736]
      2. region b:461-687 [79739]
  2. Thale cress (Arabidopsis thaliana), chloroplast [TaxId: 3702] [142208] (6)
    SQ P17597 460-667
    1. 1ybh
      complexed with cie, fad, mg, nhe, p22
      1. region a:460-667 [122893]
    2. 1yi0
      automatically matched to 1YBH A:460-667
      complexed with 1sm, fad, mg, nhe, p22
      1. region a:460-667 [123223]
    3. 1yhz
      automatically matched to 1YBH A:460-667
      complexed with 1cs, fad, mg, nhe, p22
      1. region a:460-667 [123220]
    4. 1yhy
      automatically matched to 1YBH A:460-667
      complexed with 1mm, fad, mg, nhe, p22
      1. region a:460-667 [123217]
    5. 1yi1
      automatically matched to 1YBH A:460-667
      complexed with 1tb, fad, mg, nhe, p22
      1. region a:460-667 [123226]
    6. 1z8n
      automatically matched to 1YBH A:460-667
      complexed with 1iq, fad, mg, nhe, tpp
      1. region a:460-667 [124721]
6. Catabolic acetolactate synthase [102333]
  1. Klebsiella pneumoniae [TaxId: 573] [102334] (3)
    1. 1ozh
      complexed with he3, mg, peg, pig, po4
      1. region a:367-558 [93835]
      2. region b:367-559 [93838]
      3. region c:367-558 [93841]
      4. region d:367-555 [93844]
    2. 1ozf
      complexed with mg, peg, po4, tpp
      1. region a:367-554 [93823]
      2. region b:367-554 [93826]
    3. 1ozg
      complexed with he3, mg, peg, po4
      1. region a:367-554 [93829]
      2. region b:367-554 [93832]
7. Carboxyethylarginine synthase [102335]
  1. Streptomyces clavuligerus [TaxId: 1901] [102336] (11)
    1. 2iht
      automatically matched to d1upaa3
      complexed with gol, mg, so4, tpp
      1. region a:375-572 [147687]
    2. 2iht
      automatically matched to d1upaa3
      complexed with gol, mg, so4, tpp
      1. region b:375-572 [147690]
    3. 2iht
      automatically matched to d1upaa3
      complexed with gol, mg, so4, tpp
      1. region c:375-572 [147693]
    4. 2iht
      automatically matched to d1upaa3
      complexed with gol, mg, so4, tpp
      1. region d:375-572 [147696]
    5. 2ihu
      automatically matched to d1upaa3
      complexed with gol, k, mg, tar, tp8, tp9
      1. region a:375-572 [147699]
    6. 2ihv
      automatically matched to d1upaa3
      complexed with gva, k, mg, tpp
      1. region a:375-572 [147702]
    7. 2ihv
      automatically matched to d1upaa3
      complexed with gva, k, mg, tpp
      1. region b:375-572 [147705]
    8. 2ihv
      automatically matched to d1upaa3
      complexed with gva, k, mg, tpp
      1. region d:375-572 [147708]
    9. 1upa
      complexed with mg, so4, tpp
      1. region a:375-572 [99716]
      2. region b:375-572 [99719]
      3. region c:375-563 [99722]
      4. region d:375-572 [99725]
    10. 1upb
      complexed with mg, so4, tpp
      1. region a:375-572 [99728]
      2. region b:375-572 [99731]
      3. region c:375-563 [99734]
      4. region d:375-572 [99737]
    11. 1upc
      complexed with mg, so4, tpp
      1. region a:375-572 [99740]
      2. region b:375-572 [99743]
      3. region c:375-572 [99746]
      4. region d:375-572 [99749]
      5. region e:375-572 [99752]
      6. region f:375-572 [99755]
8. Oxalyl-CoA decarboxylase [142209]
  1. Oxalobacter formigenes [TaxId: 847] [142210] (12)
    SQ P40149 370-552
    1. 2ji7
      automatically matched to d2c31a3
      complexed with adp, b3p, mg, oxt, pge
      1. region a:370-552 [148064]
    2. 2ji7
      automatically matched to d2c31a3
      complexed with adp, b3p, mg, oxt, pge
      1. region b:370-552 [148067]
    3. 2c31
      complexed with adp, mg, tzd
      1. region a:370-552 [129706]
    4. 2c31
      automatically matched to 2C31 A:370-552
      complexed with adp, mg, tzd
      1. region b:370-552 [129709]
    5. 2ji6
      automatically matched to d2c31a3
      complexed with adp, b3p, mg, oxk, pge, tpw
      1. region a:370-552 [148058]
    6. 2ji6
      automatically matched to d2c31a3
      complexed with adp, b3p, mg, oxk, pge, tpw
      1. region b:370-552 [148061]
    7. 2ji9
      automatically matched to d2c31a3
      complexed with adp, b3p, mg, tpw
      1. region a:370-552 [148076]
    8. 2ji9
      automatically matched to d2c31a3
      complexed with adp, b3p, mg, tpw
      1. region b:370-552 [148079]
    9. 2ji8
      automatically matched to d2c31a3
      complexed with adp, fyn, mg, pge, tpp
      1. region a:370-552 [148070]
    10. 2ji8
      automatically matched to d2c31a3
      complexed with adp, fyn, mg, pge, tpp
      1. region b:370-552 [148073]
    11. 2jib
      automatically matched to d2c31a3
      complexed with adp, coa, mg, pge, tpp
      1. region a:370-552 [148082]
    12. 2jib
      automatically matched to d2c31a3
      complexed with adp, coa, mg, pge, tpp
      1. region b:370-552 [148085]
TK-like PP module [88760] (5)
different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
1. Transketolase (TK), PP module [88761]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88762] (7)
    1. 1gpu
      complexed with ca, thd
      1. region a:3-337 [65454]
      2. region b:3-337 [65457]
    2. 1trk
      complexed with ca, tpp
      1. region a:3-337 [31803]
      2. region b:3-337 [31805]
    3. 1tkb
      complexed with ca, n1t
      1. region a:3-337 [31807]
      2. region b:3-337 [31809]
    4. 1tkc
      complexed with ca, m6t
      1. region a:3-337 [31811]
      2. region b:3-337 [31813]
    5. 1ngs
      complexed with ca, e4p, tpp
      1. region a:3-337 [31819]
      2. region b:3-337 [31821]
    6. 1tka
      complexed with ca, n3t
      1. region a:3-337 [31815]
      2. region b:3-337 [31817]
    7. 1ay0
      complexed with ca, tpp; mutant
      1. region a:3-337 [31823]
      2. region b:3-337 [31825]
  2. Maize (Zea mays) [TaxId: 4577] [88763] (1)
    1. 1itz
      complexed with mg, tpp
      1. region a:10-347 [76797]
      2. region b:10-347 [76800]
      3. region c:10-347 [76803]
  3. Escherichia coli [TaxId: 562] [89656] (7)
    1. 2r8o
      automatically matched to d1qgda2
      complexed with ca, edo, t5x
      1. region a:2-332 [151732]
    2. 2r8o
      automatically matched to d1qgda2
      complexed with ca, edo, t5x
      1. region b:2-332 [151735]
    3. 2r5n
      automatically matched to d1qgda2
      complexed with ca, edo, r5p, rp5, tpp
      1. region a:2-332 [151592]
    4. 2r5n
      automatically matched to d1qgda2
      complexed with ca, edo, r5p, rp5, tpp
      1. region b:2-332 [151595]
    5. 2r8p
      automatically matched to d1qgda2
      complexed with ca, edo, t6f
      1. region a:2-332 [151738]
    6. 2r8p
      automatically matched to d1qgda2
      complexed with ca, edo, t6f
      1. region b:2-332 [151741]
    7. 1qgd
      complexed with ca, so4, tpp
      1. region a:2-332 [88368]
      2. region b:2-332 [88371]
  4. Leishmania mexicana mexicana [TaxId: 44270] [117524] (1)
    SQ Q8MPM3
    1. 1r9j
      complexed with ca, tpp
      1. region a:1-336 [111723]
      2. region b:1-336 [111726]
2. Pyruvate dehydrogenase E1 component, PP module [88764]
  E1A and E1B fused together in a single-chain protein
  1. Escherichia coli [TaxId: 562] [88765] (14)
    1. 2iea
      automatically matched to d1l8aa1
      complexed with mg, tdp
      1. region a:56-470 [137295]
    2. 2iea
      automatically matched to d1l8aa1
      complexed with mg, tdp
      1. region b:56-470 [137298]
    3. 2qta
      automatically matched to d1l8aa1
      complexed with mg, tdp; mutant
      1. region a:56-470 [151334]
    4. 2qta
      automatically matched to d1l8aa1
      complexed with mg, tdp; mutant
      1. region b:56-470 [151337]
    5. 2qtc
      automatically matched to d1l8aa1
      complexed with mg, tdk; mutant
      1. region a:56-470 [151344]
    6. 2qtc
      automatically matched to d1l8aa1
      complexed with mg, tdk; mutant
      1. region b:56-470 [151347]
    7. 1l8a
      complexed with mg, tdp
      1. region a:56-470 [73677]
      2. region b:56-470 [73680]
    8. 2g28
      automatically matched to d1l8aa1
      complexed with mg, tdk
      1. region a:56-470 [134530]
    9. 2g28
      automatically matched to d1l8aa1
      complexed with mg, tdk
      1. region b:56-470 [134533]
    10. 2g25
      automatically matched to d1l8aa1
      complexed with mg, po4, tdk
      1. region a:56-470 [134524]
    11. 2g25
      automatically matched to d1l8aa1
      complexed with mg, po4, tdk
      1. region b:56-470 [134527]
    12. 1rp7
      complexed with mg, tzd
      1. region a:56-470 [97703]
      2. region b:56-470 [97706]
    13. 2g67
      automatically matched to d1l8aa1
      1. region a:56-470 [134696]
    14. 2g67
      automatically matched to d1l8aa1
      1. region b:56-470 [134699]
Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5)
parent family to TK and PFOR
heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
1. Branched-chain alpha-keto acid dehydrogenase, PP module [88767]
  1. Human (Homo sapiens) [TaxId: 9606] [88768] (23)
    SQ P12694 52-445
    1. 2bfd
      complexed with cl, gol, k, mn, mpd, tdp; mutant
      1. region a:6-400 [144988]
    2. 2bff
      complexed with gol, k, mn, tzd
      1. region a:6-400 [144989]
    3. 1x7y
      complexed with cl, gol, k, mn, tdp; mutant
      1. chain a [114944]
    4. 2bfc
      complexed with gol, k, mn, tzd; mutant
      1. region a:6-400 [144987]
    5. 2bfe
      complexed with cl, gol, k, mn, mrd, tdp; mutant
      1. region a:6-400 [146140]
    6. 1x7z
      complexed with cl, gol, k, mn, tdp; mutant
      1. chain a [114947]
    7. 1x7w
      complexed with cl, gol, k, mn, tdp; mutant
      1. chain a [114938]
    8. 2bfb
      complexed with cl, gol, k, mn, mrd, tdp; mutant
      1. region a:6-400 [146139]
    9. 2bev
      automatically matched to d1olxa_
      complexed with cl, gol, k, mn, thy
      1. region a:6-400 [128392]
    10. 2bew
      automatically matched to d1olxa_
      complexed with cl, gol, k, mn, thw
      1. region a:6-400 [128395]
    11. 1v16
      complexed with bdn, cl, gol, k, mn, tdp; mutant
      1. chain a [108240]
    12. 1wci
      automatically matched to d1olxa_
      complexed with cl, gol, k, mn, wwf
      1. region a:6-400 [120890]
    13. 1u5b
      complexed with gol, k, mn, tdp
      1. chain a [113034]
    14. 1v1r
      complexed with cl, gol, k, na, so4
      1. chain a [108272]
    15. 1olu
      complexed with gol, k, mg, tdp; mutant
      1. chain a [93335]
    16. 1v11
      complexed with bdn, cl, gol, k, mn, tdp; mutant
      1. chain a [108227]
    17. 1ols
      complexed with gol, k, mn, tdp
      1. chain a [93331]
    18. 1v1m
      complexed with bdn, cl, gol, k, mn, tdp; mutant
      1. chain a [108261]
    19. 2beu
      automatically matched to d1olxa_
      complexed with cl, gol, k, mn, so4, thv
      1. region a:6-400 [128389]
    20. 1x80
      complexed with cl, gol, k, mn, tdp
      1. chain a [114950]
    21. 1x7x
      complexed with cl, gol, k, mn, tdp; mutant
      1. chain a [114941]
    22. 1olx
      complexed with gol, k, mn, tdp; mutant
      1. chain a [93338]
    23. 1dtw
      complexed with k, mg, tdp
      1. chain a [31827]
  2. Thermus thermophilus [TaxId: 274] [102337] (4)
    1. 1umd
      complexed with coi, mg, tdp
      1. chain a [99599]
      2. chain c [99602]
    2. 1umb
      complexed with mg, tdp
      1. chain a [99587]
      2. chain c [99590]
    3. 1um9
      complexed with so4
      1. chain a [99581]
      2. chain c [99584]
    4. 1umc
      complexed with 4mv, mg, tdp
      1. chain a [99593]
      2. chain c [99596]
2. E1-beta subunit of pyruvate dehydrogenase (PP module) [89651]
  1. Human (Homo sapiens) [TaxId: 9606] [89652] (3)
    1. 2ozl
      complexed with k, mg, tpp; mutant
      1. region a:1-361 [145744]
    2. 2ozl
      automatically matched to 2OZL A:1-361
      complexed with k, mg, tpp; mutant
      1. region c:1-361 [145745]
    3. 1ni4
      complexed with k, mg, mse, tpp; mutant
      1. chain a [85728]
      2. chain c [85731]
3. 2-oxoisovalerate dehydrogenase (E1B), PP module [88769]
  chain A is alpha-subunit and chain B is beta-subunit
  1. Pseudomonas putida [TaxId: 303] [88770] (5)
    1. 1qs0
      complexed with hri, mg, tdp
      1. chain a [31829]
    2. 2bp7
      automatically matched to d1qs0a_
      1. region a:2-408 [128926]
    3. 2bp7
      automatically matched to d1qs0a_
      1. region c:2-408 [128929]
    4. 2bp7
      automatically matched to d1qs0a_
      1. region e:2-408 [128932]
    5. 2bp7
      automatically matched to d1qs0a_
      1. region g:2-408 [128935]
4. Pyruvate dehydrogenase E1-alpha, PdhA [117525]
  1. Bacillus stearothermophilus [TaxId: 1422] [117526] (2)
    SQ P21873
    1. 1w85
      complexed with k, mg, peg, tdp
      1. chain a [114335]
      2. chain c [114338]
      3. chain e [114341]
      4. chain g [114344]
    2. 1w88
      complexed with mg, tdp; mutant
      1. chain a [114349]
      2. chain c [114352]
      3. chain e [114355]
      4. chain g [114358]
PFOR PP module [88771] (1)
domains VI, I and II are arranged in the same way as the TK PP, Pyr and C domains
1. Pyruvate-ferredoxin oxidoreductase, PFOR, domains VI [88772]
  1. Desulfovibrio africanus [TaxId: 873] [88773] (17)
    1. 2c42
      automatically matched to d1b0pa2
      complexed with ca, mg, pyr, sf4, tpp
      1. region a:786-1232 [129791]
    2. 2c42
      automatically matched to d1b0pa2
      complexed with ca, mg, pyr, sf4, tpp
      1. region b:786-1232 [129796]
    3. 2c3m
      automatically matched to d1b0pa2
      complexed with ca, cl, mg, sf4, tpp
      1. region a:786-1232 [129741]
    4. 2c3m
      automatically matched to d1b0pa2
      complexed with ca, cl, mg, sf4, tpp
      1. region b:786-1232 [129746]
    5. 2c3y
      automatically matched to d1b0pa2
      complexed with ca, co2, htl, mg, sf4
      1. region a:786-1232 [129781]
    6. 2c3y
      automatically matched to d1b0pa2
      complexed with ca, co2, htl, mg, sf4
      1. region b:786-1231 [129786]
    7. 1kek
      complexed with ca, co2, fs4, htl, mg
      1. region a:786-1232 [68525]
      2. region b:786-1232 [68530]
    8. 2c3p
      automatically matched to d1b0pa2
      complexed with 1tp, ca, mg, sf4
      1. region a:786-1232 [129761]
    9. 2c3p
      automatically matched to d1b0pa2
      complexed with 1tp, ca, mg, sf4
      1. region b:786-1232 [129766]
    10. 2uza
      automatically matched to d1b0pa2
      complexed with ca, co2, htl, mg, sf4
      1. region a:786-1232 [152326]
    11. 2uza
      automatically matched to d1b0pa2
      complexed with ca, co2, htl, mg, sf4
      1. region b:786-1232 [152331]
    12. 2c3u
      automatically matched to d1b0pa2
      complexed with 2tp, ca, mg, pyr, sf4
      1. region a:786-1232 [129771]
    13. 2c3u
      automatically matched to d1b0pa2
      complexed with 2tp, ca, mg, pyr, sf4
      1. region b:786-1232 [129776]
    14. 1b0p
      complexed with ca, fs4, mg, tpp
      1. region a:786-1232 [31832]
      2. region b:786-1232 [31834]
    15. 2c3o
      automatically matched to d1b0pa2
      complexed with ca, mg, pyr, sf4, tpp
      1. region a:786-1232 [129751]
    16. 2c3o
      automatically matched to d1b0pa2
      complexed with ca, mg, pyr, sf4, tpp
      1. region b:786-1232 [129756]
    17. 2pda
      complexed with ca, fs4, mg, pyr, tpp
      1. region a:786-1232 [31836]
      2. region b:786-1232 [31838]