Protein: Acetohydroxyacid synthase catalytic subunit from Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]

SQ P07342 84-687

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thiamin diphosphate-binding fold (THDP-binding) [52517]
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
4. Superfamily: Thiamin diphosphate-binding fold (THDP-binding) [52518]
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
   uperfamily
5. Family: Pyruvate oxidase and decarboxylase PP module [88749]
   the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
6. Protein: Acetohydroxyacid synthase catalytic subunit [88758]
7. Species: Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88759]
   SQ P07342 84-687

PDB Entry Domains:

1. 1t9b
   complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
   1. region a:461-687 [112336]
   2. region b:461-687 [112339]
2. 1t9c
   complexed with 1sm, fad, k, mg, p22, p23
   1. region a:461-687 [112342]
   2. region b:461-687 [112345]
3. 1t9d
   complexed with 1mm, fad, k, mg, p22, p25, yf1
   1. region a:461-687 [112348]
   2. region b:461-687 [112351]
   3. region c:461-687 [112354]
   4. region d:461-687 [112357]
4. 1t9a
   complexed with 1tb, fad, k, mg, p23, yf3, yf4
   1. region a:461-687 [112330]
   2. region b:461-687 [112333]
5. 1jsc
   complexed with 2hp, fad, k, mg, tpp
   1. region a:461-648 [67226]
   2. region b:464-649 [67229]
6. 1n0h
   complexed with ayd, cie, dtt, fad, k, mg, tpp
   1. region a:461-687 [79736]
   2. region b:461-687 [79739]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk