Protein: Acetohydroxyacid synthase catalytic subunit from Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]

SQ P07342 84-687

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thiamin diphosphate-binding fold (THDP-binding) [52517]
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
4. Superfamily: Thiamin diphosphate-binding fold (THDP-binding) [52518]
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
   uperfamily
5. Family: Pyruvate oxidase and decarboxylase Pyr module [88724]
   the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
6. Protein: Acetohydroxyacid synthase catalytic subunit [88733]
7. Species: Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88734]
   SQ P07342 84-687

PDB Entry Domains:

1. 1t9b
   complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
   1. region a:89-263 [112335]
   2. region b:89-263 [112338]
2. 1t9c
   complexed with 1sm, fad, k, mg, p22, p23
   1. region a:89-263 [112341]
   2. region b:89-263 [112344]
3. 1t9d
   complexed with 1mm, fad, k, mg, p22, p25, yf1
   1. region a:89-263 [112347]
   2. region b:89-263 [112350]
   3. region c:89-263 [112353]
   4. region d:89-263 [112356]
4. 1t9a
   complexed with 1tb, fad, k, mg, p23, yf3, yf4
   1. region a:89-263 [112329]
   2. region b:89-263 [112332]
5. 1jsc
   complexed with 2hp, fad, k, mg, tpp
   1. region a:83-270 [67225]
   2. region b:82-272 [67228]
6. 1n0h
   complexed with ayd, cie, dtt, fad, k, mg, tpp
   1. region a:83-270 [79735]
   2. region b:83-270 [79738]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk