Protein: Pyruvate oxidase from Lactobacillus plantarum [TaxId: 1590]

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thiamin diphosphate-binding fold (THDP-binding) [52517]
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
4. Superfamily: Thiamin diphosphate-binding fold (THDP-binding) [52518]
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
   uperfamily
5. Family: Pyruvate oxidase and decarboxylase PP module [88749]
   the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
6. Protein: Pyruvate oxidase [88754]
7. Species: Lactobacillus plantarum [TaxId: 1590] [88755]

PDB Entry Domains:

1. 2ez9
   automatically matched to d1powa3
   complexed with fad, mg, na, tdk; mutant
   1. region a:366-593 [132629]
2. 2ez9
   automatically matched to d1powa3
   complexed with fad, mg, na, tdk; mutant
   1. region b:366-593 [132632]
3. 2ez8
   automatically matched to d1powa3
   complexed with fad, mg, na, pyr, tdl; mutant
   1. region a:366-593 [132623]
4. 2ez8
   automatically matched to d1powa3
   complexed with fad, mg, na, pyr, tdl; mutant
   1. region b:366-593 [132626]
5. 2ez4
   automatically matched to d1powa3
   complexed with fad, mg, na, po4, tpp; mutant
   1. region a:366-593 [132612]
6. 2ez4
   automatically matched to d1powa3
   complexed with fad, mg, na, po4, tpp; mutant
   1. region b:366-593 [132615]
7. 2ezu
   automatically matched to d1powa3
   complexed with fad, htl, mg, na, pyr; mutant
   1. region a:366-593 [132641]
8. 2ezu
   automatically matched to d1powa3
   complexed with fad, htl, mg, na, pyr; mutant
   1. region b:366-593 [132644]
9. 1pox
   complexed with fad, gol, mg, na, tpp; mutant
   1. region a:366-593 [31794]
   2. region b:366-593 [31796]
10. 2ezt
    automatically matched to d1powa3
    complexed with fad, mg, na, po4, pyr, tdm; mutant
    1. region a:366-593 [132635]
11. 2ezt
    automatically matched to d1powa3
    complexed with fad, mg, na, po4, pyr, tdm; mutant
    1. region b:366-593 [132638]
12. 1pow
    complexed with fad, mg, tpp
    1. region a:366-593 [31798]
    2. region b:366-593 [31800]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk