Protein: Catabolic acetolactate synthase from Klebsiella pneumoniae [TaxId: 573]

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thiamin diphosphate-binding fold (THDP-binding) [52517]
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
4. Superfamily: Thiamin diphosphate-binding fold (THDP-binding) [52518]
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
   uperfamily
5. Family: Pyruvate oxidase and decarboxylase PP module [88749]
   the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
6. Protein: Catabolic acetolactate synthase [102333]
7. Species: Klebsiella pneumoniae [TaxId: 573] [102334]

PDB Entry Domains:

1. 1ozh
   complexed with he3, mg, peg, pig, po4
   1. region a:367-558 [93835]
   2. region b:367-559 [93838]
   3. region c:367-558 [93841]
   4. region d:367-555 [93844]
2. 1ozf
   complexed with mg, peg, po4, tpp
   1. region a:367-554 [93823]
   2. region b:367-554 [93826]
3. 1ozg
   complexed with he3, mg, peg, po4
   1. region a:367-554 [93829]
   2. region b:367-554 [93832]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk