Protein: Transketolase (TK), PP module from Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thiamin diphosphate-binding fold (THDP-binding) [52517]
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
4. Superfamily: Thiamin diphosphate-binding fold (THDP-binding) [52518]
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
   uperfamily
5. Family: TK-like PP module [88760]
   different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
6. Protein: Transketolase (TK), PP module [88761]
7. Species: Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [88762]

PDB Entry Domains:

1. 1gpu
   complexed with ca, thd
   1. region a:3-337 [65454]
   2. region b:3-337 [65457]
2. 1trk
   complexed with ca, tpp
   1. region a:3-337 [31803]
   2. region b:3-337 [31805]
3. 1tkb
   complexed with ca, n1t
   1. region a:3-337 [31807]
   2. region b:3-337 [31809]
4. 1tkc
   complexed with ca, m6t
   1. region a:3-337 [31811]
   2. region b:3-337 [31813]
5. 1ngs
   complexed with ca, e4p, tpp
   1. region a:3-337 [31819]
   2. region b:3-337 [31821]
6. 1tka
   complexed with ca, n3t
   1. region a:3-337 [31815]
   2. region b:3-337 [31817]
7. 1ay0
   complexed with ca, tpp; mutant
   1. region a:3-337 [31823]
   2. region b:3-337 [31825]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk