Class: All alpha proteins

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]

Folds:

1. Globin-like [46457] (2)
   core: 6 helices; folded leaf, partly opened
2. Long alpha-hairpin [46556] (20)
   2 helices; antiparallel hairpin, left-handed twist
3. Type I dockerin domain [63445] (1)
   tandem repeat of two calcium-binding loop-helix motifs, distinct from the EF-hand
4. LEM/SAP HeH motif [63450] (6)
   helix-extended loop-helix; parallel helices
5. SOCS box-like [158234] (1)
   helix-loop-helix motif with orthogonally packed helices
6. RPB6/omega subunit-like [63561] (1)
   core: 2 helices and adjacent loops
7. KRAB domain (Kruppel-associated box) [109639] (1)
   2 helices: one short, one long; aromatic-rich iterface
8. Cytochrome c [46625] (1)
   core: 3 helices; folded leaf, opened
9. DNA/RNA-binding 3-helical bundle [46688] (14)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
10. Another 3-helical bundle [81602] (5)
    topologically similar to the DNA/RNA-binding bundles; distinct packing
11. RuvA C-terminal domain-like [46928] (9)
    3 helices; bundle, right-handed twist
12. S13-like H2TH domain [81297] (1)
    core: 3-4 helices
13. Putative DNA-binding domain [46954] (1)
    core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different
14. Spectrin repeat-like [46965] (16)
    3 helices; bundle, closed, left-handed twist; up-and-down
15. immunoglobulin/albumin-binding domain-like [46996] (11)
    3 helices; bundle, closed, left-handed twist; up-and-down; mirror topology to the spectrin-like fold
16. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47004] (1)
    3 helices; bundle, closed, right-handed twist; up-and-down
17. ChaB-like [140375] (1)
    3 helices, the first one is shorter than the other two; bundle, capped by a small, C-terminal beta-hairpin
18. Protozoan pheromone-like [47013] (2)
    3 helices; bundle, closed, left-handed twist, up-and-down
19. Acyl-CoA binding protein-like [47026] (2)
    core: 3 helices; bundle, closed, left-handed twist; up-and-down
20. YqgQ-like [158378] (1)
    3 helices, bundle, left-handed twist, extended overside connection between the first and second helices
21. Kix domain of CBP (creb binding protein) [47039] (1)
    3 helices; bundle, partly opened
22. RAP domain-like [47044] (1)
    3 helices, the first one is shorter than the other two; bundle, partly opened
23. VHP, Villin headpiece domain [47049] (1)
    3 short helices; irregular array
24. BSD domain-like [140382] (1)
    core: 3 helices; triangular array; the extra N-terminal and C-terminal helices form a coiled coil structure
25. TAF(II)230 TBP-binding fragment [47054] (1)
    3 short helices; irregular array
26. S15/NS1 RNA-binding domain [47059] (1)
    3 helices; irregular array
27. Frizzled cysteine-rich domain [63500] (1)
    Core: 3 helices; irregular array; disulfide-rich
28. T4 endonuclease V [47076] (1)
    3 helices; irregular array
29. Fertilization protein [47081] (1)
    core: 3 helices; bundle, closed, right-handed twist; up-and-down
30. PGBD-like [47089] (1)
    core: 3 helices; bundle, closed, left-handed twist; parallel
31. HMG-box [47094] (1)
    3 helices; irregular array
32. Histone-fold [47112] (1)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
33. Open three-helical up-and-down bundle [47143] (7)
    core: 3 helices; bundle, open
34. beta-catenin-interacting protein ICAT [81729] (1)
    core: 3 helices; irregular array
35. DNA polymerase III theta subunit-like [116730] (1)
    3 helices; irregular array
36. Four-helical up-and-down bundle [47161] (28)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
37. PTS-regulatory domain, PRD [63519] (1)
    core: 4 helices; bundle, closed, right-handed twist; 1 crossover connection
38. Ferritin-like [47239] (6)
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
39. 4-helical cytokines [47265] (1)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
40. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1)
    core: 4 helices; bundle; one loop crosses over one side of the bundle
41. Acyl carrier protein-like [47335] (3)
    4 helices, bundle; helix 3 is shorter than others; up-and-down
42. Bromodomain-like [47363] (15)
    4 helices; bundle; minor mirror variant of up-and-down topology
43. ROP-like [47379] (8)
    4 helices; dimer of identical alpha-hairpin subunits; bundle, closed, left-handed twist
44. Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit [47390] (1)
    4 helices; bundle, closed, right-handed twist
45. Orange domain-like [158456] (1)
    4 helices; dimer of identical alpha-hairpin subunits;
46. Soluble domain of poliovirus core protein 3a [89042] (1)
    4 helices; bundle, closed, right-handed twist
47. Transcription factor IIA (TFIIA), alpha-helical domain [47395] (1)
    4 helices; bundle, closed, right-handed twist
48. Ectatomin subunits [47400] (1)
    4 helices; bundle, closed, left-handed twist
49. Dimerisation interlock [47405] (4)
    4 helices; bundle, closed, right-handed twist
50. lambda repressor-like DNA-binding domains [47412] (1)
    core: 4 helices; folded leaf, closed
51. Signal peptide-binding domain [47445] (1)
    4 helices; orthogonal array
52. A DNA-binding domain in eukaryotic transcription factors [47453] (1)
    4 helices; the long C-terminal helix protrudes from the domain and binds to DNA
53. HLH-like [47458] (2)
    4-helices; bundle, closed, left-handed twist; 2 crossover connections
54. HAMP domain-like [158471] (1)
    dimer of helix-loop-helix segments; distict from the HLH-like fold; parallel four-helical bundle with two overside connections
55. EF Hand-like [47472] (4)
    core: 4 helices; array of 2 hairpins, opened
56. CH domain-like [47575] (3)
    core: 4 helices: bundle
57. Domain of poly(ADP-ribose) polymerase [47586] (1)
    core: 4 helices: bundle; unusual topology
58. SWIB/MDM2 domain [47591] (1)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
59. Pre-protein crosslinking domain of SecA [81766] (1)
    core: 4 helices: bundle; flanked by two short beta-hairpins
    duplication: consists of two structural repeats
60. Ribbon-helix-helix [47597] (1)
    core: 4 helices; array of 2 hairpins, opened
61. GST C-terminal domain-like [47615] (1)
    core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix
62. Methionine synthase domain-like [47643] (3)
    4 helices; bundle, left-handed twist; right-handed superhelix
63. KaiA/RbsU domain [101214] (1)
    4 helices; bundle, right-handed twist; right-handed superhelix
64. STAT-like [47654] (6)
    4 long helices; bundle, left-handed twist (coiled coil); right-handed superhelix
65. N-cbl like [47667] (5)
    4 helices; bundle, left-handed twist; left-handed superhelix
66. Replisome organizer (g39p helicase loader/inhibitor protein) [89063] (1)
    4 helices; bundle, right-handed twist; left-handed superhelix
67. Hypothetical protein YqbG [116914] (1)
    core: 4 helices; bundle, right-handed twist; left-handed superhelix
68. DnaD domain-like [158498] (1)
    4 helices; bundle, right-handed twist; left-handed superhelix
69. C-terminal domain of B transposition protein [47680] (1)
    4 helices; irregular array
70. HAND domain of the nucleosome remodeling ATPase ISWI [101223] (1)
    4 helices; irregular array
71. N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [89068] (1)
    4 helices; irregular array
72. Anaphylotoxins (complement system) [47685] (1)
    4 helices; irregular array, disulfide-linked
73. Cytochrome c oxidase subunit h [47693] (1)
    4 helices; irregular array, disulfide-linked
74. Crustacean CHH/MIH/GIH neurohormone [81777] (1)
    4 helices; irregular array, disulfide-linked
75. C-terminal domain of DFF45/ICAD (DFF-C domain) [81782] (1)
    4 helices; folded leaf; right-handed superhelix
76. BH2638-like [158503] (1)
    4 helices, folded leaf, right-handed superhelix; some similarity to the DFF-C domain fold (scop_cf 81782)
77. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47698] (1)
    4 helices; folded leaf; right-handed superhelix
78. p53 tetramerization domain [47718] (1)
    core: 4 helices; bundle
79. Bcr-Abl oncoprotein oligomerization domain [69035] (1)
    core: 4 long helices; bundle
80. Domain of early E2A DNA-binding protein, ADDBP [47723] (1)
    4 helices; bundle, partly opened
81. IHF-like DNA-binding proteins [47728] (1)
    core: 4 helices; bundle, partly opened, capped with a beta-sheet
82. TraM-like [140580] (1)
    multihelical oligomeric protein; structure of whole subunit is not known; the N-terminal part is implicated in DNA binding, the middle region forms tetrameric parallel coiled coil, surrounded by the C-terminal helices
83. CO dehydrogenase ISP C-domain like [47740] (1)
    core: 4 helices, bundle
84. Protein HNS-dependent expression A; HdeA [47751] (1)
    4 helices; the three last helices form a bundle similar to that of the RuvA C-domain
85. PABP domain-like [63569] (2)
    4 helices; an orthogonal array
86. Chemotaxis receptor methyltransferase CheR, N-terminal domain [47756] (1)
    4 helices; an orthogonal array
87. Dcp2 domain-like [140585] (1)
    4 helices; orthogonal array of two alpha hairpins
88. Type III secretion system domain [140590] (1)
    core: 4 helices, orthogonal array; right-handed superhelix
89. YugE-like [116921] (1)
    4-helices; bundle; right-handed twist
90. PWI domain [101232] (1)
    4 helices; up-and-down bundle; topological similarity to the bromodomain-like and SAM domain-like folds
91. PAH2 domain [47761] (1)
    4 helices; open up-and-down bundle; binds alpha-helical peptides
92. Myosin phosphatase inhibitor 17kDa protein, CPI-17 [81789] (1)
    4 helices; open up-and-down bundle; flexible N-terminal tail
93. XPC-binding domain [101237] (1)
    4 helices; array
94. DinB/YfiT-like putative metalloenzymes [109853] (1)
    core: 4 helices; bundle, closed, left-handed twist; an unusual topology with a higher contact order
95. EspA/CesA-like [116926] (1)
    4 helices; bundle, closed, left ight-handed twist; interlocked (hetero)dimer of 2-helical subunits
96. NblA-like [109858] (1)
    4 helices; dimer of identical alpha-hairpin subunits; open bundle
97. EF2947-like [140606] (1)
    4 helices; "diamond" array; duplication: N-terminal and C-terminal pairs of helices are related by pseudo dyad
98. EB1 dimerisation domain-like [140611] (1)
    dimeric 4-helical bundle with a coiled coil at one end formed by the longer N-terminal helices
99. SAM domain-like [47768] (16)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
100. Retroviral matrix proteins [47835] (1)
     4-5 helices; right-handed superhelix
101. Flavivirus capsid protein C [101256] (1)
     core: 5 helices; right-handed superhelix; swapped dimer with the two long C-terminal helices
102. Hepatitis B viral capsid (hbcag) [47851] (1)
     5 helices; array; two long helices form a hairpin that dimerizes into a 4-helical bundle
103. Apolipophorin-III [47856] (1)
     5 helices; bundle, closed, left-handed twist
104. Methenyltetrahydrofolate cyclohydrolase-like [101261] (1)
     5 helices; bundle, closed, left-handed twist
105. A middle domain of Talin 1 [109879] (1)
     5 helices; bundle, closed, left-handed twist; helices 2-5 adopt the Four-helical up-and-down bundle fold (scop_cf 47161)
106. I/LWEQ domain [109884] (1)
     5 helices; bundle, closed, left-handed twist
107. RNA-binding protein She2p [116941] (1)
     5 helices; bundle, closed, left-handed twist; topological similarity to the middle domain of the L-aspartase-like fold (scop_cf 48556)
108. Hyaluronidase domain-like [140656] (3)
     5 helices; bundle, closed, left-handed twist; up-and-down (meander) topology
109. YoaC-like [140669] (1)
     5 helices; bundle, one crossover connection, the arrangement of the first four helices is similar to the KaiA/RbsU domain fold (scop_cf 101214)
110. Saposin-like [47861] (2)
     5 helices; folded leaf, closed
111. Annexin [47873] (1)
     5 helices; folded leaf, closed
112. TAFH domain-like [158552] (1)
     5 helices; folded leaf, closed
113. Transducin (alpha subunit), insertion domain [47894] (1)
     5 helices; folded leaf
114. Wiscott-Aldrich syndrome protein, WASP, C-terminal domain [47911] (1)
     5 helices; irregular array; left-handed superhelix
115. Left-handed superhelix [47916] (4)
     core: 4-5 helices; bundle; left-handed superhelix
116. ATPD N-terminal domain-like [47927] (2)
     core: 5 helices; bundle
117. ERP29 C domain-like [47932] (2)
     5 helices; bundle
118. Functional domain of the splicing factor Prp18 [47937] (1)
     core: 5 helices; bundle
119. Retrovirus capsid protein, N-terminal core domain [47942] (1)
     core: 5 helices; bundle
120. GINS helical bundle-like [158572] (1)
     5 helices, staggered bundle;
121. Jann4075-like [158586] (1)
     core: 5 helices; the C-terminal helix is surrounded by the others; similarity to some EF-hand domains
122. Cyclin-like [47953] (1)
     core: 5 helices; one helix is surrounded by the others
123. Arp2/3 complex 21 kDa subunit ARPC3 [69059] (1)
     5 helices; one helix is surrounded by the others
124. RNase III domain-like [69064] (1)
     core: 5 helices; one helix is surrounded by the others
125. Ribosomal protein S7 [47972] (1)
     core: 5 helices; contains one more helix and a beta-hairpin outside the core
126. post-AAA+ oligomerization domain-like [48018] (1)
     core: 5 helices: bundle
127. PAP/OAS1 substrate-binding domain [81632] (1)
     core: 5-helical bundle; up-and-down; right-handed twist
128. Anti-sigma factor AsiA [69069] (1)
     core: 5 helices: orthogonal array
129. Antibiotic binding domain of TipA-like multidrug resistance regulators [89081] (1)
     5 helices: orthogonal array
130. Surp module (SWAP domain) [109904] (1)
     5 helices: irregular array
131. YgfY-like [109909] (1)
     5 helices; array; forms a tight dimer in crystals
132. Hypothetical protein YhaI [109914] (1)
     core: 5 helices; orthogonal array; folding similarity to the TipA-S domain (1ny9)
133. Hypothetical protein At3g22680 [109919] (1)
     5 helices; array; probable biological unit is a homodimer
134. SP0561-like [140682] (1)
     5 helices; array; includes extra N-terminal and C-terminal short strands forming parrallel beta-sheet ladder
135. RbcX-like [158614] (1)
     5 helices per subunit; irregular array of short and long helices; swapping of the C-terminal helices in the dimer
136. YheA-like [158621] (1)
     5 helices; "kinked" antiparallel coiled coil; forms flexible oligomeric assemblies via two different dimerisation interfaces
137. RPA2825-like [158633] (1)
     5 helices, array; long flexible loop between helices 1 and 2; the remaining helices are arranged similar to the PGBD-like fold (scop_cf 47089)
138. ENT-like [158638] (1)
     5 helices, irregular array, right-handed superhelix
139. YfmB-like [140687] (1)
     5 helices, array; buried N-terminal helix; some topological similarity (circular permutation?) to the Nucleotidyltransferase substrate binding subunit/domain (scop_sf 81593)
140. N-terminal domain of adenylylcyclase associated protein, CAP [101277] (1)
     6 helices: bundle; left-handed twist, up-and-down topology
141. IpaD-like [140692] (1)
     6 helices; bundle, up-and-down; can be divided into two four-helical bundles sharing two helices (3 and 6), which are twice longer than the rest
142. Iron-dependent repressor protein, dimerization domain [47978] (1)
     6 helices, homodimer of 3-helical domains
143. Glutamyl tRNA-reductase dimerization domain [69074] (1)
     6 helices, homodimer of 3-helical domains
144. GRIP domain [101282] (1)
     6 helices, homodimer of 3-helical domains
145. BAR/IMD domain-like [116747] (1)
     6 helices, homodimer of 3-helical domains
146. L27 domain [101287] (1)
     6 helices, heterodimer of 3-helical domains
147. Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain [109924] (1)
     dimer of 3-helical segments; consists of two subdomains: 4-helical bundle and coiled coil
148. Phage replication organizer domain [140712] (1)
     6 helices, homodimer of 3-helical domains
149. YejL-like [158650] (1)
     6 helices; intertwined homodimer of three-helical subunits, bundle
150. Mediator hinge subcomplex-like [140717] (1)
     6 helices; heterodimer of structurally similar subunits; the N-terminal hairpins form a four-helical bundle, whereas the C-terminal helices form coiled coil structure
151. DEATH domain [47985] (1)
     6 helices: closed bundle; greek-key; internal pseudo twofold symmetry
152. GntR ligand-binding domain-like [48007] (1)
     core: 6 helices: closed bundle; greek-key; internal pseudo twofold symmetry
153. AF0941-like [140725] (1)
     6 helices, arranged into two interconnected 3-helical bundles; can also be described as a 'kinked' four-helical bundle; right-handed superhelix
154. NusB-like [48012] (1)
     6 helices: bundle; one central helix is surrounded by 5 others
155. YutG-like [101306] (1)
     core: 6 helices; bundle; one central helix is surrounded by 5 others
156. N-terminal domain of DnaB helicase [48023] (1)
     6 helices: array
157. Invasion protein A (SipA) , C-terminal actin binding domain [101311] (1)
     6 helices: orthogonal array
158. MtlR-like [158667] (1)
     multihelical; 8-helical up-and-down bundle
159. Guanido kinase N-terminal domain [48033] (1)
     irregular array of 6 short helices
160. Scaffolding protein gpD of bacteriophage procapsid [48044] (1)
     core: 6 helices; one central helix is surrounded by 5 others
161. Hemocyanin, N-terminal domain [48049] (1)
     6 helices; bundle; one central helix is surrounded by 5 others
162. Sama2622-like [158674] (1)
     core: 6 helices; bundle; one central helix is surrounded by 5 others
163. Di-copper centre-containing domain [48055] (1)
     multihelical
164. DBL homology domain (DH-domain) [48064] (1)
     multihelical; core: 5-helical bundle
165. LigA subunit of an aromatic-ring-opening dioxygenase LigAB [48075] (1)
     multihelical; contains compact array of 6 short helices
166. RuBisCo LSMT C-terminal, substrate-binding domain [81821] (1)
     multihelical; irregular array of long and short helices
167. Methyl-coenzyme M reductase alpha and beta chain C-terminal domain [48080] (1)
     multihelical bundle; contains buried central helix
168. YcfC-like [101321] (1)
     multihelical; contains two buried central helices
169. PA2201 C-terminal domain-like [140730] (1)
     multihelical; seven-helical bundle with buried central helix
170. Rv1873-like [140735] (1)
     multihelical; contains unusually short buried central helix
171. RUN domain-like [140740] (1)
     multihelical; 3-helical bundle similar to one half of the DEATH domain fold is flanked by two alpha-hairpins forming a four-helical bundle; the axes of the three-helical and four-helical bundles are aproximately orthogonal to each other
172. SipA N-terminal domain-like [140745] (1)
     multihelical; bundle; the last helix is buried inside the bundle
173. Transcription factor STAT-4 N-domain [48091] (1)
     multihelical; can be divided into two subdomains
174. TerB-like [158681] (1)
     multihelical; contains two central helices; duplication: there are two three-helical repeats related by pseudo twofold symmetry
175. Regulator of G-protein signaling, RGS [48096] (1)
     multihelical; consists of two all-alpha subdomains
     contains a 4-helical bundle with left-handed twist and up-and-down topology
176. SopE-like GEF domain [81831] (1)
     multihelical; consists of two all-alpha subdomains each containing a 3-helical bundle with right-handed twist
177. Variable surface antigen VlsE [74747] (1)
     multihelical; consists of two all-alpha subdomains; contains a 4-helical bundle with left-handed twist and up-and-down topology
178. YgfB-like [101326] (1)
     multihelical; consists of two tightly associated 3-helical bundles with different twists
179. Hypothetical protein MTH393 [101331] (1)
     multihelical; consists of two all-alpha subdomains; dimer
180. PG0816-like [140752] (1)
     multihelical; comprises two helical bundles, both are topologically similar to the RuvA C-terminal domain-like fold (scop_cf 46928)
181. UraD-like [158693] (1)
     multihelical; irregular array of long and short helices
182. Sec63 N-terminal domain-like [158701] (1)
     multihelical; consists of two helical subdomains
183. Carbamoyl phosphate synthetase, large subunit connection domain [48107] (1)
     multihelical; consists of two all-alpha subdomains
     possible duplication: subdomains have similar topologies
184. Heme-dependent peroxidases [48112] (1)
     multihelical; consists of two all-alpha domains
185. Ribosomal protein L19 (L19e) [48139] (1)
     multihelical; consists of two different 3-helical domains connected by a long, partly helical linker
186. PSPTO4464-like [158709] (1)
     multihelical; consists of two subdomains at the ends of a long connecting helix
187. GatB/YqeY motif [89094] (1)
     multihelical; consists of two different alpha-helical bundles (4-helical and 3-helical)
188. YfbU-like [116959] (1)
     multihelical; consist of two subdomains; forms 24-mer with the N-terminal sudbomains packing around the 4-fold axis and the C-terminal domains interacting at the 2-fold and 3-fold axes
189. MG296-like [158714] (1)
     multihelical; in crystal forms helical polymers by swapping the two N-terminal helices to the next subunit in polymer; three subunits per turn of polymer helix
190. Hypothetical protein MPN330 [116964] (1)
     multihelical; consists of three different 4-helical bundles
191. HD-domain/PDEase-like [109603] (1)
     multihelical; consists of two different alpha-helical bundles
192. Superantigen MAM [101343] (1)
     multihelical; consists of two different alpha-helical bundles
193. Influenza virus matrix protein M1 [48144] (1)
     multihelical; consists of two different all-alpha subdomains, 4 helices each
194. DNA-glycosylase [48149] (1)
     multihelical; consists of two all-alpha domains
195. An anticodon-binding domain of class I aminoacyl-tRNA synthetases [48162] (1)
     multihelical; consists of two all-alpha domains
196. Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) [101352] (1)
     multihelical; consists of two all-alpha subdomains
197. R1 subunit of ribonucleotide reductase, N-terminal domain [48167] (1)
     multihelical consists of two all-alpha subdomains
     subdomain 1 (residues 10-100) is a 4-helical bundle
198. BEACH domain [81836] (1)
     multihelical, complex architecture
199. Cryptochrome/photolyase FAD-binding domain [48172] (1)
     multihelical; consists of two all-alpha subdomains
200. 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1)
     multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
201. Uteroglobin-like [48200] (1)
     multihelical
202. alpha/alpha toroid [48207] (6)
     multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies
203. Citrate synthase [48255] (1)
     multihelical; consists of two all-alpha domains
204. Cytochrome P450 [48263] (1)
     multihelical
205. Flagellar transcriptional activator FlhD [63591] (1)
     multihelical; forms intertwined dimer of identical 5-helical subunits
206. HP0242-like [158751] (1)
     multihelical; intertwined homodimer of four-helical subunits, forming catenated triangular ring-like structures; pseudo knot
207. SMc04008-like [158756] (1)
     multihelcal; intertwined homodimer; there are 4 core helices in each subunits; contains putative metal ion-binding motif MxxxxxCxxC in the conserved surface site
208. Ribosomal protein L7/12, oligomerisation (N-terminal) domain [48299] (1)
     multihelical; intertwined tetramer
209. Class II MHC-associated invariant chain ectoplasmic trimerization domain [48304] (1)
     multihelical; intertwined trimer of identical 3-helical subunits
210. Aldehyde ferredoxin oxidoreductase, C-terminal domains [48309] (1)
     multihelical; consists of two all-alpha domains
211. Acid phosphatase/Vanadium-dependent haloperoxidase [48316] (1)
     multihelical; core: 5-helical bundle; binds cofactor at the beginning of third helix
212. BRCA2 helical domain [81871] (1)
     multihelical; contains a 3-helical bundle surrounded by several shorter helices
213. BRCA2 tower domain [81877] (1)
     multihelical; contains a 3-helical Hin recombinase-like subdomain and two long dimerisation helices
214. H-NS histone-like proteins [81274] (1)
     multihelical oligomeric protein; structure of whole subunit is not known yet but are probably composed of three different domains
215. Sigma2 domain of RNA polymerase sigma factors [88945] (1)
     multihelical; consists of a conserved 4-helical core and a variable insert subdomain
216. DNA repair protein MutS, domain III [48333] (1)
     multihelical; consists of 2 all-alpha subdomains
217. Helical scaffold and wing domains of SecA [81885] (1)
     multihelical; consists of 2 all-alpha subdomains
218. all-alpha NTP pyrophosphatases [101385] (1)
     multihelical: dimeric 4-helical bundle surrounded by other helices; oligomerizes further in a tetramer
219. Hsp90 co-chaperone CDC37 [101390] (1)
     multihelical; consists of 2 all-alpha subdomains connected by a long helix
220. Nop domain [89123] (1)
     multihelical; array of longer and shorter helices; contains an alpha-hairpin dimerisation subdomain
221. YidB-like [140803] (1)
     multihelical; three strings of short helices are packed across one longer helix
222. Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain [48339] (1)
     multihelical; bundle of longer and shorter helices
223. A virus capsid protein alpha-helical domain [48344] (1)
     multihelical; three-helical bundle in the core is surrounded by non-conserved helices
224. P40 nucleoprotein [101398] (1)
     multihelical; consists of two subdomains
225. Rhabdovirus nucleoprotein-like [140808] (1)
     multihelical, consist of two helical domains; each domain contains a buried helix
226. GTPase activation domain, GAP [48349] (1)
     multihelical
227. Ras GEF [48365] (1)
     multihelical
228. Telomeric repeat binding factor (TRF) dimerisation domain [63599] (1)
     multihelical; can be divided into an alpha-alpha superhelix domain and a long alpha-hairpin dimerization domain
229. Poly A polymerase C-terminal region-like [81890] (1)
     multihelical; can be divided into three subdomains (neck, body and tail)
230. alpha-alpha superhelix [48370] (24)
     multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
231. GUN4-like [140868] (1)
     multihelical; open array, trapping inside an extended region before the C-terminal helix
232. Lipoxigenase [48483] (1)
     multihelical
     large nearly all-alpha domain
233. gene 59 helicase assembly protein [48492] (1)
     multihelical; consists of two all-alpha subdomains
234. Tetracyclin repressor-like, C-terminal domain [48497] (1)
     multihelical; interlocked (homo)dimer
235. Skp1 dimerisation domain-like [81384] (1)
     multihelical; interlocked heterodimer with F-box proteins
236. F-box domain [81385] (1)
     multihelical; interlocked heterodimer with the Skp1 dimerisation domain
237. Nuclear receptor ligand-binding domain [48507] (1)
     multihelical; 3 layers or orthogonally packed helices
238. Phospholipase C/P1 nuclease [48536] (1)
     multihelical
239. ATP-dependent DNA ligase DNA-binding domain [117017] (1)
     multihelical; duplication: contains two intertwined structural repeats related by pseudo twofold symmetry
240. DNA primase DnaG, C-terminal domain [117022] (1)
     multihelical; segment-swapped dimer
241. PriB N-terminal domain-like [140913] (1)
     multihelical bundle; contains buried central helix; also includes the PriA interface-forming insert subdomain (alpha+beta)
242. VPS9 domain [109992] (1)
     multihelical; consist of two subdomains
243. Triger factor/SurA peptide-binding domain-like [109997] (1)
     multihelical; irregular array of long and short helices
244. DNA terminal protein [140918] (1)
     multihelical, open array; contains the C-terminal four-helical bundle, left-handed superhelix
245. Glycolipid transfer protein, GLTP [110003] (1)
     multihelical; 2 layers or orthogonally packed helices
246. Hypothetical protein MG354 [110008] (1)
     multihelical bundle; contains buried central helix
247. Duffy binding domain-like [140923] (1)
     consist of two subdomains, each containing a three-helical bundle
248. Fic-like [140930] (1)
     multihelical; one central helix is surrounded by seven helices
249. Her-1 [110013] (1)
     multihelical; consists of two topologically similar alpha-helical bundles
250. ERO1-like [110018] (1)
     multihelical; consists of 2 four-helical bundles
251. Serum albumin-like [48551] (1)
     multihelical; one domain consists of two similar disulfide-linked subdomains
252. L-aspartase-like [48556] (1)
     multihelical, consists of three all-alpha domains
253. Formin homology 2 domain (FH2 domain) [101446] (1)
     multihelical, consists of three all-alpha domains
254. Terpenoid synthases [48575] (1)
     multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
255. GroEL equatorial domain-like [48591] (1)
     multihelical; 8 helices arranged in 2 parallel layers
256. TorD-like [89154] (1)
     multihelical; bundle
257. Chorismate mutase II [48599] (1)
     multihelical; core: 6 helices, bundle
258. Peridinin-chlorophyll protein [48607] (1)
     multihelical: forms a boat-shaped protein shell around cofactors
259. Heme oxygenase-like [48612] (1)
     multihelical; bundle
260. Indolic compounds 2,3-dioxygenase-like [140958] (1)
     multihelical; bundle, contains interrupted helices
261. AhpD-like [69117] (1)
     multihelical; contains 4-helical bundle and 2-helical arm
262. Double Clp-N motif [81922] (1)
     multihelical; array
263. Orange carotenoid protein, N-terminal domain [81929] (1)
     multihelical; array
264. DhaL-like [101472] (1)
     multihelical; bundle
265. ADP-ribosylglycohydrolase [101477] (1)
     multihelical; bundle
266. Topoisomerase V catalytic domain-like [140978] (1)
     multihelical; irregular array; contains small amount of beta-structure and a 3-helical bundle with a variant homeofomain-like fold and HTH motif (scop_cf 46688)
267. PTPA-like [140983] (1)
     multihelical
268. Tex N-terminal region-like [158831] (1)
     multihelical; irregular array of long and short helices; can be divided into several subdomains
269. AGR_C_984p-like [158836] (1)
     multihelical, consists of two subdomains; duplication: there are two 5-helical structural repeats, one in each subdomain
270. PMT central region-like [158841] (1)
     multihelical; comprises two four-helical bundles of different topologies and an irregular helical array packed against a small beta-sheet
271. FtsH protease domain-like [140989] (1)
     array of 6 helices and a 2-stranded beta-ribbon
272. Gametocyte protein Pfg27 [89161] (1)
     multihelical; bundle
273. N-terminal domain of bifunctional PutA protein [81934] (1)
     multihelical; array
274. Cysteine alpha-hairpin motif [47071] (1)
     core: alpha-hairpin crosslinked with two disulfides
275. Phospholipase A2, PLA2 [48618] (1)
     common core: 2 helices, disulfide-linked, and a calcium-binding loop
276. Fungal elicitin [48646] (1)
     5 helices: irregular disulfide-linked array; also contains a small beta-hairpin
277. Tetraspanin [48651] (1)
     5 helices: irregular disulfide-linked array; form homodimer
278. GDNF receptor-like [110034] (1)
     5 helices: irregular disulfide-linked array; topological similarity to the Fungal elicitin fold (scop_cf 48646)
279. FinO-like [48656] (1)
     6 helices: irregular non-globular array; also contains two small beta-hairpins
280. Nuclear receptor coactivator interlocking domain [69124] (1)
     3 helices, non-globular array; forms interlocked heterodimers with its targets
281. Hermes dimerisation domain [140995] (1)
     multihelical, intertwinned dimer of two 4-helical strings
282. Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain [101488] (1)
     5 helices, non-globular array; wraps around the N-terminal tail of its target
283. Non-globular all-alpha subunits of globular proteins [48661] (14)
     not a true fold
284. Multiheme cytochromes [48694] (1)
     variable number of helices and little beta structure; not a true fold

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk