Fold: DBL homology domain (DH-domain)

multihelical; core: 5-helical bundle

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]
3. Fold: DBL homology domain (DH-domain) [48064]
   multihelical; core: 5-helical bundle

Superfamilies:

1. DBL homology domain (DH-domain) [48065] (1)
   uperfamily
   1. DBL homology domain (DH-domain) [48066] (10)
      Pfam 00621
      1. Son of sevenless-1 (sos-1) [48067]
         1. Human (Homo sapiens) [TaxId: 9606] [48068] (3)
            SQ Q07889 189-1046
      2. beta-pix [48069]
         1. Human (Homo sapiens) [TaxId: 9606] [48070] (1)
      3. RhoGEF Vav [48071]
         1. Mouse (Mus musculus) [TaxId: 10090] [48072] (1)
      4. GEF of TIAM1 (T-Lymphoma invasion and metastasis inducing protein 1) [48073]
         1. Mouse (Mus musculus) [TaxId: 10090] [48074] (1)
      5. Dbl's big sister, Dbs [74743]
         1. Mouse (Mus musculus) [TaxId: 10090] [74744] (4)
            SQ Q64096 624-958 # 98% sequence identity; the rat sequence Q63406 region 499-833 is 100% identical to the PDB sequence
      6. GEF of intersectin [74745]
         1. Human (Homo sapiens) [TaxId: 9606] [74746] (1)
      7. Triple functional domain protein TRIO [109935]
         1. Human (Homo sapiens) [TaxId: 9606] [109936] (2)
            SQ O75962 1231-1535
      8. Rho guanine nucleotide exchange factor 12 [109937]
         1. Human (Homo sapiens), gamma isoform [TaxId: 9606] [109938] (2)
            SQ Q9NZN5 766-1138
      9. Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF [116957]
         1. Human (Homo sapiens) [TaxId: 9606] [116958] (1)
            SQ O15085 714-1081
      10. Rho guanine nucleotide exchange factor 9, Collybistin [158679]
          1. Rat (Rattus norvegicus) [TaxId: 10116] [158680] (1)
             SQ Q9QX73 97-299

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk