Structural Classification of Proteins
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Family: DBL homology domain (DH-domain)

Pfam 00621

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: DBL homology domain (DH-domain) [48064]
    multihelical; core: 5-helical bundle
  4. Superfamily: DBL homology domain (DH-domain) [48065]
    link to SUPERFAMILY database - Superfamily
  5. Family: DBL homology domain (DH-domain) [48066]
    Pfam 00621

Protein Domains:

  1. Son of sevenless-1 (sos-1) [48067]
    1. Human (Homo sapiens) [TaxId: 9606] [48068] (3) picpic
      SQ Q07889 189-1046
  2. beta-pix [48069]
    1. Human (Homo sapiens) [TaxId: 9606] [48070] (1) picpic
  3. RhoGEF Vav [48071]
    1. Mouse (Mus musculus) [TaxId: 10090] [48072] (1) picpic
  4. GEF of TIAM1 (T-Lymphoma invasion and metastasis inducing protein 1) [48073]
    1. Mouse (Mus musculus) [TaxId: 10090] [48074] (1) picpic
  5. Dbl's big sister, Dbs [74743]
    1. Mouse (Mus musculus) [TaxId: 10090] [74744] (4) picpic
      SQ Q64096 624-958 # 98% sequence identity; the rat sequence Q63406 region 499-833 is 100% identical to the PDB sequence
  6. GEF of intersectin [74745]
    1. Human (Homo sapiens) [TaxId: 9606] [74746] (1) picpic
  7. Triple functional domain protein TRIO [109935]
    1. Human (Homo sapiens) [TaxId: 9606] [109936] (2) picpic
      SQ O75962 1231-1535
  8. Rho guanine nucleotide exchange factor 12 [109937]
    1. Human (Homo sapiens), gamma isoform [TaxId: 9606] [109938] (2) picpic
      SQ Q9NZN5 766-1138
  9. Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF [116957]
    1. Human (Homo sapiens) [TaxId: 9606] [116958] (1) picpic
      SQ O15085 714-1081
  10. Rho guanine nucleotide exchange factor 9, Collybistin [158679]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [158680] (1) picpic
      SQ Q9QX73 97-299

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk