Structural Classification of Proteins
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Fold: 4-helical cytokines

core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: 4-helical cytokines [47265]
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

Superfamilies:

  1. 4-helical cytokines [47266] (3)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
    link to SUPERFAMILY database - Superfamily
    1. Long-chain cytokines [47267] (14) picpic
    2. Short-chain cytokines [47286] (14) picpic
    3. Interferons/interleukin-10 (IL-10) [47305] (13) picpic
      contains an additional helix in one of the crossover connections
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
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