Structural Classification of Proteins
home mail help root up expand collapse

Family: Long-chain cytokines

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: 4-helical cytokines [47265]
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. Superfamily: 4-helical cytokines [47266]
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
    link to SUPERFAMILY database - Superfamily
  5. Family: Long-chain cytokines [47267]

Protein Domains:

  1. Granulocyte-colony stimulating factor (G-CSF) [47268]
    1. Human (Homo sapiens) [TaxId: 9606] [47269] (5) picpic
    2. Cow (Bos taurus) [TaxId: 9913] [47270] (1) picpic
    3. Dog (Canis familiaris) [TaxId: 9615] [47271] (2) picpic
  2. Interleukin-6 [47272]
    1. Human (Homo sapiens) [TaxId: 9606] [47273] (4) picpic
    2. Human herpesvirus 8, Kaposi's sarcoma herpes-virus [TaxId: 37296] [63528] (1) picpic
  3. Leukemia inhibitory factor (LIF) [47274]
    1. Mouse (Mus musculus) [TaxId: 10090] [47275] (2) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [63529] (4) picpic
  4. Growth hormone, somatotropin [47276]
    1. Human (Homo sapiens) [TaxId: 9606] [47277] (9) picpic
  5. Prolactin (placental lactogen) [47278]
    1. Sheep (Ovis aries) [TaxId: 9940] [47279] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [89035] (2) picpic
  6. Ciliary neurotrophic factor (CNTF) [47280]
    1. Human (Homo sapiens) [TaxId: 9606] [47281] (1) picpic
  7. Leptin (obesity protein) [47282]
    1. Human (Homo sapiens) [TaxId: 9606] [47283] (1) picpic
  8. Oncostatin M [47284]
    1. Human (Homo sapiens) [TaxId: 9606] [47285] (1) picpic
  9. Heterodimeric interleukin-12 alpha chain [63530]
    1. Human (Homo sapiens) [TaxId: 9606] [63531] (1) picpic
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk