Structural Classification of Proteins
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Fold: Regulator of G-protein signaling, RGS

multihelical; consists of two all-alpha subdomains
contains a 4-helical bundle with left-handed twist and up-and-down topology

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Regulator of G-protein signaling, RGS [48096]
    multihelical; consists of two all-alpha subdomains
    contains a 4-helical bundle with left-handed twist and up-and-down topology

Superfamilies:

  1. Regulator of G-protein signaling, RGS [48097] (1)
    link to SUPERFAMILY database - Superfamily
    1. Regulator of G-protein signaling, RGS [48098] (9)
      1. Regulator of G-protein signaling 4, RGS4 [48099]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [48100] (3) picpic
      2. RGS9, RGS domain [48101]
        1. Cow (Bos taurus) [TaxId: 9913] [48102] (3) picpic
      3. Galpha interacting protein, GaIP [48103]
        1. Human (Homo sapiens) [TaxId: 9606] [48104] (1) picpic
      4. Axin RGS-homologous domain [48105]
        1. Human (Homo sapiens) [TaxId: 9606] [48106] (2) picpic
      5. p115RhoGEF [63584]
        1. Human (Homo sapiens) [TaxId: 9606] [63585] (1) picpic
      6. Pdz-RhoGEF RGS-like domain [63586]
        contains extra helices in the C-terminal extension
        1. Human (Homo sapiens) [TaxId: 9606] [63587] (1) picpic
      7. G-protein coupled receptor kinase 2, N-terminal domain [89090]
        1. Cow (Bos taurus) [TaxId: 9913] [89091] (6) picpic
      8. Regulator of G-protein signaling 18, RGS18 [140750]
        1. Human (Homo sapiens) [TaxId: 9606] [140751] (1) picpic
          SQ Q9NS28 75-206
      9. Regulator of G-protein signaling 16, RGS16 [158689]
        1. Human (Homo sapiens) [TaxId: 9606] [158690] (2) picpic
          SQ O15492 65-184
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk