Fold: Four-helical up-and-down bundle

core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]
3. Fold: Four-helical up-and-down bundle [47161]
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

Superfamilies:

1. Apolipoprotein [47162] (1)
   uperfamily
2. Aspartate receptor, ligand-binding domain [47170] (1)
   uperfamily
3. Cytochromes [47175] (2)
   Heme-containing proteins
   uperfamily
4. Hemerythrin-like [47188] (1)
   uperfamily
5. TMV-like viral coat proteins [47195] (1)
   uperfamily
6. FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1)
   uperfamily
7. Proteasome activator [47216] (1)
   uperfamily
8. alpha-catenin/vinculin-like [47220] (2)
   uperfamily
9. FAT domain of focal adhesion kinase [68993] (1)
   uperfamily
10. Oxygen-evolving enhancer protein 3, [101112] (1)
    uperfamily
11. Histidine-containing phosphotransfer domain, HPT domain [47226] (6)
    contains additional, fifth helix at the N-terminus
    uperfamily
12. Bacterial GAP domain [47233] (1)
    contains extra helices in the loops at one end of the bundle
    uperfamily
13. Outer surface protein C (OspC) [63515] (1)
    uperfamily
14. Flagellar export chaperone FliS [101116] (1)
    can form closed, open and helix-swapped bundles
    uperfamily
15. Domain of the SRP/SRP receptor G-proteins [47364] (1)
    uperfamily
16. FAD-dependent thiol oxidase [69000] (1)
    uperfamily
17. Group V grass pollen allergen [81736] (1)
    uperfamily
18. Nucleotidyltransferase substrate binding subunit/domain [81593] (4)
    uperfamily
19. RecG, N-terminal domain [69008] (1)
    uperfamily
20. Colicin D immunity protein [101125] (1)
    uperfamily
21. Nickel-containing superoxide dismutase, NiSOD [109770] (1)
    uperfamily
22. Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain [109775] (1)
    contains extra alpha+beta subdomain formed by the N- and C-termini.
    uperfamily
23. Domain from hypothetical 2610208m17rik protein [109779] (1)
    uperfamily
24. TrmE connector domain [116878] (1)
    uperfamily
25. YppE-like [140415] (1)
    flattened bundle at one end with helices 2 and coming in contact and separating helices 1 and 3
    uperfamily
26. MW0975(SA0943)-like [140423] (1)
    open bundle; there is a long groove between helices 1 and 4
    uperfamily
27. VPS28 C-terminal domain-like [140427] (1)
    uperfamily
28. TM1646-like [158397] (1)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk