Structural Classification of Proteins
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Protein: Immunoglobulin heavy chain variable domain, VH from Human (Homo sapiens), cluster 1 [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: V set domains (antibody variable domain-like) [48727]
  6. Protein: Immunoglobulin heavy chain variable domain, VH [88543]
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species: Human (Homo sapiens), cluster 1 [TaxId: 9606] [88544]

PDB Entry Domains:

  1. 1rzf picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab E51
    complexed with gol, ioh
    1. region h:2-113 [98150] picpiclink
  2. 2fx7 picpicxrefxrefxref
    automatically matched to d1hzhh1
    complexed with gol; mutant
    1. region h:1-113 [134276] picpiclink
  3. 1n0x picpicxrefxrefxref
    part of an anti HIV-1 Fab
    complexed with cxs, gol, k, orn, so4
    1. region h:1-113 [91528] picpiclink
    2. region k:1-113 [91530] picpiclink
  4. 2nxy picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with hez, nag, trs; mutant
    1. region d:3001-3128 [138749] picpiclink
  5. 1rz7 picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 48D
    complexed with gol
    1. region h:1-113 [98133] picpiclink
  6. 2ny2 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with edo, hez, nag, suc; mutant
    1. region d:3001-3128 [138774] picpiclink
  7. 1iqd picpicxrefxrefxrefxref
    part of intact IgG B12 antibody
    mutant
    1. region b:1-114 [62646] picpiclink
  8. 1rzg picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 412D
    complexed with suc
    1. region a:1-113 [98154] picpiclink
    2. region c:2-113 [98158] picpiclink
  9. 2ny3 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with nag, suc; mutant
    1. region d:3001-3128 [138780] picpiclink
  10. 2ny4 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with hez, nag, suc; mutant
    1. region d:3001-3128 [138786] picpiclink
  11. 1rhh picpicxrefxrefxref
    part of HIV-1 neutralizing Fab x5
    1. region b:3-113 [97475] picpiclink
    2. region d:4-113 [97479] picpiclink
  12. 2ny1 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with nag, suc; mutant
    1. region d:3001-3128 [138768] picpiclink
  13. 2nxz picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with edo, hez, ipa, nag, suc; mutant
    1. region d:3001-3128 [138755] picpiclink
  14. 1vge picpicxrefxrefxref
    part of humanized Fab TR1.9
    1. region h:1-122 [20095] picpiclink
  15. 2fx9 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    complexed with orq
    1. region h:1-113 [134296] picpiclink
  16. 2fx9 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    complexed with orq
    1. region i:1-113 [134298] picpiclink
  17. 1tzg picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    complexed with gol
    1. region h:1-113 [119396] picpiclink
  18. 1tzg picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    complexed with gol
    1. region i:1-113 [119398] picpiclink
  19. 2ny0 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with hez, nag; mutant
    1. region d:3001-3128 [138762] picpiclink
  20. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    mutant
    1. region h:1-113 [134280] picpiclink
  21. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    mutant
    1. region i:1-113 [134282] picpiclink
  22. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    mutant
    1. region j:1-113 [134284] picpiclink
  23. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1hzhh1
    mutant
    1. region k:1-113 [134286] picpiclink
  24. 1yym picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with edo, ipa, mpt, nag, ndg, vlm; mutant
    1. region h:1-113 [124233] picpiclink
  25. 1yym picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with edo, ipa, mpt, nag, ndg, vlm; mutant
    1. region r:1001-1113 [124240] picpiclink
  26. 2i5y picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with bif, mpt, nag, ndg, vlm
    1. region h:1-113 [137072] picpiclink
  27. 2i5y picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with bif, mpt, nag, ndg, vlm
    1. region r:1-113 [137079] picpiclink
  28. 2ny7 picpicxrefxrefxrefxref
    automatically matched to d1hzhh1
    complexed with nag; mutant
    1. region h:1-113 [138800] picpiclink
  29. 2dd8 picpicxrefxrefxrefxref
    complexed with nag, po4
    1. region h:2-113 [145073] picpiclink
  30. 2g75 picpicxrefxrefxrefxrefxrefxref
    automatically matched to 2DD8 H:2-113
    1. region a:2-113 [147086] picpiclink
  31. 2g75 picpicxrefxrefxrefxrefxrefxref
    automatically matched to 2DD8 H:2-113
    1. region c:2-113 [147090] picpiclink
  32. 1rz8 picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 17B
    1. region b:1-113 [98139] picpiclink
    2. region d:1-113 [98143] picpiclink
  33. 2i60 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with ipa, mpt, nag, ndg, vlm
    1. region h:2-113 [137082] picpiclink
  34. 2i60 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with ipa, mpt, nag, ndg, vlm
    1. region r:1-113 [137089] picpiclink
  35. 2ny5 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with nag, suc; mutant
    1. region h:3001-3128 [138790] picpiclink
  36. 1g9m picpicxrefxrefxrefxrefxrefxref
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with fuc, ioh, nag; mutant
    1. region h:1-129 [20263] picpiclink
  37. 1rzj picpicxrefxrefxrefxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 17B
    complexed with fuc, ioh, nag; mutant
    1. region h:1-113 [98201] picpiclink
  38. 1yyl picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with bif, mpt, nag, ndg, vlm; mutant
    1. region h:1-113 [124223] picpiclink
  39. 1yyl picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with bif, mpt, nag, ndg, vlm; mutant
    1. region r:1001-1113 [124230] picpiclink
  40. 1gc1 picpicxrefxrefxrefxrefxrefxref
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with fuc, nag; mutant
    1. region h:1-129 [20265] picpiclink
  41. 1hzh picpicxrefxrefxrefxrefxref
    part of intact IgG B12 antibody
    complexed with fuc, gal, man, nag
    1. region h:1-113 [61437] picpiclink
    2. region k:1-113 [61441] picpiclink
  42. 2ny6 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rz8b1
    complexed with nag, suc; mutant
    1. region d:3001-3128 [138798] picpiclink
  43. 1rzk picpicxrefxrefxrefxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 17B
    complexed with nag; mutant
    1. region h:1-113 [98208] picpiclink
  44. 1g9n picpicxrefxrefxrefxrefxrefxref
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with nag; mutant
    1. region h:1-129 [20267] picpiclink
  45. 2qad picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rzga1
    complexed with edo, mla, nag
    1. region d:1-113 [150205] picpiclink
  46. 2qad picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1rzga1
    complexed with edo, mla, nag
    1. region h:1-113 [150209] picpiclink
  47. 1rzi picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 47E
    1. region b:1-113 [98168] picpiclink
    2. region d:1-113 [98172] picpiclink
    3. region f:1-113 [98176] picpiclink
    4. region h:1-113 [98180] picpiclink
    5. region j:1-113 [98184] picpiclink
    6. region l:1-113 [98188] picpiclink
    7. region n:1-113 [98192] picpiclink
    8. region p:1-113 [98196] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk