Structural Classification of Proteins
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Family: MPP-like

Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: LuxS/MPP-like metallohydrolase [63410]
    core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta
  4. Superfamily: LuxS/MPP-like metallohydrolase [63411]
    Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues
    link to SUPERFAMILY database - Superfamily
  5. Family: MPP-like [63412]
    Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal

Protein Domains:

  1. Mitochondrial processing peptidase (MPP) beta chain [64300]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64301] (4) picpic
  2. Mitochondrial processing peptidase (MPP) alpha chain [64302]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64303] (4) picpic
  3. Cytochrome bc1 core subunit 1 [63408]
    1. Cow (Bos taurus) [TaxId: 9913] [55997] (26) picpic
      SQ P31800
    2. Chicken (Gallus gallus) [TaxId: 9031] [55998] (3) picpic
    3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64304] (14) picpic
  4. Cytochrome bc1 core subunit 2 [63409]
    1. Cow (Bos taurus) [TaxId: 9913] [56000] (12) picpic
      SQ P23004
    2. Chicken (Gallus gallus) [TaxId: 9031] [56001] (17) picpic
    3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64305] (14) picpic
  5. Presequence protease 1, PREP1 [143498]
    duplication: comprises four domains of this fold; similar to the MPP alpha-beta heterodimer
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [143499] (8) picpic
      SQ Q9LJL3 100-356! SQ Q9LJL3 357-624! SQ Q9LJL3 625-882! SQ Q9LJL3 883-1078
  6. Protease III [143500]
    duplication: comprises four domains of this fold
    1. Escherichia coli [TaxId: 562] [143501] (4) picpic
      SQ P05458 24-263! SQ P05458 264-503! SQ P05458 504-732! SQ P05458 733-960
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk