Structural Classification of Proteins
home mail help root up expand collapse

Superfamily: Growth factor receptor domain

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Knottins (small inhibitors, toxins, lectins) [57015]
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. Superfamily: Growth factor receptor domain [57184]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Growth factor receptor domain [57185] (9)
    1. Insulin-like growth factor-binding protein-5 (IGFBP-5) [57186]
      1. Human (Homo sapiens) [TaxId: 9606] [57187] (2)
        1. 1h59 picpicxref
          complex with IGF
          1. chain b [70881] picpiclink
        2. 1boe picpic
          1. chain a [44187] picpiclink
    2. Type 1 insulin-like growth factor receptor Cys-rich domain [57188]
      contains 3 cystine-knot subdomains and 4 single-disulfide cystine knot-like subdomains
      1. Human (Homo sapiens) [TaxId: 9606] [57189] (1)
        1. 1igr picpicxref
          complexed with fuc, man, nag, so4
          1. region a:150-299 [44188] picpiclink
    3. Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains [75668]
      1. Human (Homo sapiens) [TaxId: 9606] [75669] (1)
        1. 1m6b picpicxref
          complexed with nag, so4
          1. region a:166-310 [74523] picpiclink
          2. region a:480-580 [74524] picpiclink
          3. region b:166-310 [74527] picpiclink
          4. region b:480-611 [74528] picpiclink
    4. EGF receptor Cys-rich domains [82887]
      1. Human (Homo sapiens) [TaxId: 9606] [82888] (15)
        1. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region a:481-502 [154771] picpiclink
        2. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region b:481-502 [154773] picpiclink
        3. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region e:481-502 [154777] picpiclink
        4. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region i:481-502 [154783] picpiclink
        5. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region m:481-502 [154787] picpiclink
        6. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region p:481-502 [154791] picpiclink
        7. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region s:481-502 [154795] picpiclink
        8. 3b2u picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, so4
          1. region v:481-502 [154799] picpiclink
        9. 1mox picpicxrefxref
          complexed with TGF-alpha
          complexed with cd, cl, fuc, man, nag, pt
          1. region a:163-311 [91374] picpiclink
          2. region a:481-500 [91375] picpiclink
          3. region b:163-311 [91378] picpiclink
          4. region b:481-501 [91379] picpiclink
        10. 1yy9 picpicxrefxref
          automatically matched to d1ivoa3
          complexed with bma, man, nag, ndg
          1. region a:163-311 [124209] picpiclink
        11. 1yy9 picpicxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag, ndg
          1. region a:481-512 [124210] picpiclink
        12. 1nql picpicxrefxref
          complexed with EGF
          complexed with aso, nag
          1. region a:163-311 [86035] picpiclink
          2. region a:481-614 [86036] picpiclink
        13. 3c09 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag
          1. region a:481-500 [155812] picpiclink
        14. 3c09 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1ivoa4
          complexed with bma, man, nag
          1. region d:481-500 [155816] picpiclink
        15. 1ivo picpicxrefxref
          complexed with EGF
          complexed with nag
          1. region a:163-311 [76847] picpiclink
          2. region a:481-512 [76848] picpiclink
          3. region b:163-311 [76851] picpiclink
          4. region b:481-512 [76852] picpiclink
    5. Protooncoprotein Her2 extracellular domain [82889]
      1. Human (Homo sapiens) [TaxId: 9606] [82890] (2)
        1. 1n8z picpicxrefxrefxrefxrefxref
          complexed with nag, so4
          1. region c:166-322 [80324] picpiclink
          2. region c:489-607 [80325] picpiclink
        2. 1s78 picpicxrefxrefxrefxrefxref
          complexed with man, nag
          1. region a:166-322 [98618] picpiclink
          2. region a:489-564 [98619] picpiclink
          3. region b:166-322 [98622] picpiclink
          4. region b:489-577 [98623] picpiclink
      2. Rat (Rattus norvegicus) [TaxId: 10116] [82891] (1)
        1. 1n8y picpicxref
          complexed with nag
          1. region c:166-322 [80316] picpiclink
          2. region c:489-608 [80317] picpiclink
    6. Insulin-like growth factor-binding protein 4 [161120]
      1. Human (Homo sapiens) [TaxId: 9606] [161121] (2)
        SQ P22692 24-103
        1. 1wqj picpicxref
          1. region b:3-82 [144560] picpiclink
        2. 2dsr picpicxrefxref
          automatically matched to 1WQJ B:3-82
          1. region b:3-82 [145093] picpiclink
    7. Insulin receptor [161122]
      1. Human (Homo sapiens) [TaxId: 9606] [161123] (1)
        SQ P06213 184-338
        1. 2dtg picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          mutant
          1. region e:157-311 [145105] picpiclink
    8. Insulin-like growth factor-binding protein 4, IGFBP4 [161124]
      1. Human (Homo sapiens) [TaxId: 9606] [161125] (3)
        SQ P22692 22-113
        1. 2dsp picpicxref
          1. region b:1-92 [145088] picpiclink
        2. 2dsq picpicxrefxrefxrefxref
          automatically matched to 2DSP B:1-92
          1. region a:2-92 [145089] picpiclink
        3. 2dsq picpicxrefxrefxrefxref
          automatically matched to 2DSP B:1-92
          1. region b:3-89 [145090] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk