Fold: Knottins (small inhibitors, toxins, lectins)

disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

Lineage:

1. Root: scop
2. Class: Small proteins [56992]
   Usually dominated by metal ligand, heme, and/or disulfide bridges
3. Fold: Knottins (small inhibitors, toxins, lectins) [57015]
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

Superfamilies:

1. Plant lectins/antimicrobial peptides [57016] (2)
   uperfamily
2. Plant inhibitors of proteinases and amylases [57027] (1)
   uperfamily
3. Cyclotides [57038] (4)
   macrocyclic plant knottins closed with the formation of an Asn-Gly peptide
   uperfamily
4. Gurmarin-like [57048] (2)
   uperfamily
5. Agouti-related protein [57055] (1)
   uperfamily
6. omega toxin-like [57059] (5)
   uperfamily
7. Scorpion toxin-like [57095] (5)
   uperfamily
8. Cellulose-binding domain [57180] (1)
   uperfamily
9. Growth factor receptor domain [57184] (1)
   uperfamily
10. Colipase-like [57190] (1)
    uperfamily
11. EGF/Laminin [57196] (7)
    uperfamily
12. Bromelain inhibitor VI (cysteine protease inhibitor) [57243] (1)
    uperfamily
13. Bowman-Birk inhibitor, BBI [57247] (1)
    uperfamily
14. Elafin-like [57256] (1)
    uperfamily
15. Leech antihemostatic proteins [57262] (2)
    uperfamily
16. Granulin repeat [57277] (1)
    uperfamily
17. Satiety factor CART (cocaine and amphetamine regulated transcript) [64546] (1)
    uperfamily
18. DPY module [90148] (1)
    uperfamily
19. Bubble protein [103565] (1)
    uperfamily

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk