Family: Platelet-derived growth factor-like

Lineage:

1. Root: scop
2. Class: Small proteins [56992]
   Usually dominated by metal ligand, heme, and/or disulfide bridges
3. Fold: Cystine-knot cytokines [57500]
   disulfide-rich fold; common core is all-beta
4. Superfamily: Cystine-knot cytokines [57501]
   uperfamily
5. Family: Platelet-derived growth factor-like [57502]

Protein Domains:

1. Platelet-derived growth factor BB [57503]
   1. Human (Homo sapiens) [TaxId: 9606] [57504] (1)
      1. 1pdg
         1. chain a [44748]
         2. chain b [44749]
         3. chain c [44750]
2. Vascular endothelial growth factor, VEGF [57505]
   1. Human (Homo sapiens) [TaxId: 9606] [57506] (25)
      SQ P15692 40-133
      1. 1flt
         1. chain v [44751]
         2. chain w [44752]
      2. 1vpp
         1. chain v [44753]
         2. chain w [44754]
      3. 2vpf
         1. chain a [44755]
         2. chain b [44756]
         3. chain c [44757]
         4. chain d [44758]
         5. chain e [44759]
         6. chain f [44760]
         7. chain g [44761]
         8. chain h [44762]
      4. 1bj1
         complexed with so4
         1. chain v [44763]
         2. chain w [44764]
      5. 1vpf
         1. chain a [44767]
         2. chain b [44768]
         3. chain c [44769]
         4. chain d [44770]
      6. 1cz8
         complexed with so4; mutant
         1. chain v [44765]
         2. chain w [44766]
      7. 1tzh
         1. chain v [107485]
         2. chain w [107486]
      8. 2fjg
         automatically matched to d1katv_
         complexed with so4
         1. region v:14-108 [133607]
      9. 2fjg
         automatically matched to d1katv_
         complexed with so4
         1. region w:14-107 [133608]
      10. 1tzi
          1. chain v [107491]
      11. 1qty
          1. chain v [44771]
          2. chain w [44772]
          3. chain r [44773]
          4. chain s [44774]
      12. 2fjh
          automatically matched to d1katv_
          1. region v:14-108 [133609]
      13. 2fjh
          automatically matched to d1katv_
          1. region w:14-108 [133610]
      14. 2qr0
          automatically matched to d1katv_
          1. region c:13-107 [151238]
      15. 2qr0
          automatically matched to d1katv_
          1. region d:13-107 [151239]
      16. 2qr0
          automatically matched to d1katv_
          1. region i:13-107 [151248]
      17. 2qr0
          automatically matched to d1katv_
          1. region j:13-107 [151249]
      18. 2qr0
          automatically matched to d1katv_
          1. region o:13-107 [151258]
      19. 2qr0
          automatically matched to d1katv_
          1. region p:13-107 [151259]
      20. 2qr0
          automatically matched to d1katv_
          1. region u:13-107 [151268]
      21. 2qr0
          automatically matched to d1katv_
          1. region v:13-107 [151269]
      22. 1kat
          complexed with a phage-derived peptide antagonist, chains X and Y
          1. chain v [77309]
          2. chain w [77310]
      23. 1mkk
          disulfide deficient mutant
          1. chain a [79240]
          2. chain b [79241]
      24. 1mjv
          disulfide deficient mutant
          1. chain a [79214]
          2. chain b [79215]
      25. 1mkg
          disulfide deficient mutant
          1. chain a [79234]
          2. chain b [79235]
          3. chain c [79236]
          4. chain d [79237]
   2. Aspic viper (Vipera aspis aspis) [TaxId: 8706] [118255] (1)
      SQ P67863 1-100 # svVEGF (toxin); vammin
      1. 1wq8
         complexed with tmn
         1. chain a [114832]
   3. Russell's viper (Daboia russelli russelli) [TaxId: 8707] [118256] (1)
      SQ P67861 2-95 # svVEGF (toxin); VR-1
      1. 1wq9
         1. chain a [114833]
         2. chain b [114834]
3. Placenta growth factor-1, PLGF-1 [64560]
   1. Human (Homo sapiens) [TaxId: 9606] [64561] (2)
      1. 1fzv
         complexed with mpd
         1. chain a [60159]
         2. chain b [60160]
      2. 1rv6
         complexed with b3p
         1. chain v [97912]
         2. chain w [97913]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk