Structural Classification of Proteins
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Protein: Immunoglobulin heavy chain variable domain, VH from Human (Homo sapiens), cluster 4 [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: V set domains (antibody variable domain-like) [48727]
  6. Protein: Immunoglobulin heavy chain variable domain, VH [88543]
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species: Human (Homo sapiens), cluster 4 [TaxId: 9606] [101505]

PDB Entry Domains:

  1. 3c2a picpicxrefxref
    automatically matched to d1q1jh1
    1. region h:1-113 [155872] picpiclink
  2. 3c2a picpicxrefxref
    automatically matched to d1q1jh1
    1. region i:1-113 [155874] picpiclink
  3. 1q1j picpicxrefxrefxref
    part of anti HIV-1 Fab 447-52d
    1. region h:1-113 [95581] picpiclink
    2. region i:1-113 [95583] picpiclink
  4. 2b4c picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1q1jh1
    complexed with fuc, nag, ndg, so4, xyl; mutant
    1. region h:4-113 [127822] picpiclink

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk