Structural Classification of Proteins
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Superfamily: EGF/Laminin

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Knottins (small inhibitors, toxins, lectins) [57015]
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. Superfamily: EGF/Laminin [57196]
    link to SUPERFAMILY database - Superfamily

Families:

  1. EGF-type module [57197] (27)
    1. Factor IX (IXa) [57198]
      1. Human (Homo sapiens) [TaxId: 9606] [57199] (7)
        1. 1edm picpic
          complexed with ca
          1. chain b [44203] picpiclink
          2. chain c [44204] picpiclink
        2. 2ec9 picpicxrefxref
          automatically matched to d1pfxl1
          complexed with 24x, ca, fuc, glc
          1. region l:46-82 [146786] picpiclink
        3. 2ec9 picpicxrefxref
          automatically matched to d1pfxl2
          complexed with 24x, ca, fuc, glc
          1. region l:91-140 [146787] picpiclink
        4. 1rfn picpicxref
          complexed with ca, pbz, tbu
          1. chain b [44205] picpiclink
        5. 2zp0 picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with bgc, ca, fuc, pi0
          1. region l:46-82 [154745] picpiclink
        6. 2zp0 picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with bgc, ca, fuc, pi0
          1. region l:91-140 [154746] picpiclink
        7. 1ixa picpic
          1. chain a [44206] picpiclink
      2. Pig (Sus scrofa) [TaxId: 9823] [57200] (31)
        1. 2c4f picpicxrefxrefxref
          automatically matched to d1pfxl1
          complexed with ca, fuc, gil, glc, nag
          1. region l:46-82 [129806] picpiclink
        2. 2c4f picpicxrefxrefxref
          automatically matched to d1pfxl2
          complexed with ca, fuc, gil, glc, nag
          1. region l:91-140 [129807] picpiclink
        3. 2a2q picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with ca, cl, fuc, glc, mg, na, pbz, zn
          1. region l:46-82 [126053] picpiclink
        4. 2a2q picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with ca, cl, fuc, glc, mg, na, pbz, zn
          1. region l:91-140 [126054] picpiclink
        5. 2aer picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with ben, ca, cl, fuc, glc, mg, na, zn
          1. region l:46-82 [126641] picpiclink
        6. 2aer picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with ben, ca, cl, fuc, glc, mg, na, zn
          1. region l:91-140 [126642] picpiclink
        7. 1wtg picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with 3bp, bgc, ca, fuc
          1. region l:46-82 [121263] picpiclink
        8. 1wtg picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with 3bp, bgc, ca, fuc
          1. region l:91-140 [121264] picpiclink
        9. 2fir picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with ca, cl, fuc, glc, mg, na, zn
          1. region l:46-82 [133532] picpiclink
        10. 2fir picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with ca, cl, fuc, glc, mg, na, zn
          1. region l:91-140 [133533] picpiclink
        11. 1z6j picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with ca, mg, py3
          1. region l:46-82 [124524] picpiclink
        12. 1z6j picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with ca, mg, py3
          1. region l:91-140 [124525] picpiclink
        13. 1wun picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with bgc, ca, fuc, p5b
          1. region l:46-82 [121299] picpiclink
        14. 1wun picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with bgc, ca, fuc, p5b
          1. region l:91-140 [121300] picpiclink
        15. 1wqv picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with bgc, ca, fuc, psm
          1. region l:46-82 [121174] picpiclink
        16. 1wqv picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with bgc, ca, fuc, psm
          1. region l:91-140 [121175] picpiclink
        17. 1w0y picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with 771, bgc, ca, cac, fuc
          1. region l:46-82 [120568] picpiclink
        18. 1w0y picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with 771, bgc, ca, cac, fuc
          1. region l:91-140 [120569] picpiclink
        19. 1wss picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with 3cb, bgc, ca, fuc
          1. region l:46-82 [121239] picpiclink
        20. 1wss picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with 3cb, bgc, ca, fuc
          1. region l:91-140 [121240] picpiclink
        21. 1wv7 picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with 5pi, bgc, ca, fuc
          1. region l:46-82 [121321] picpiclink
        22. 1wv7 picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with 5pi, bgc, ca, fuc
          1. region l:91-140 [121322] picpiclink
        23. 2aei picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with 03r, ca, cac
          1. region l:46-82 [126632] picpiclink
        24. 2aei picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with 03r, ca, cac
          1. region l:91-140 [126633] picpiclink
        25. 1w2k picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with 380, bgc, ca, cac, fuc
          1. region l:46-82 [120585] picpiclink
        26. 1w2k picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with 380, bgc, ca, cac, fuc
          1. region l:91-140 [120586] picpiclink
        27. 2b8o picpicxrefxrefxrefxref
          automatically matched to d1pfxl1
          complexed with ca, cl, fuc, glc, mg, na, zn
          1. region l:46-82 [128096] picpiclink
        28. 2b8o picpicxrefxrefxrefxref
          automatically matched to d1pfxl2
          complexed with ca, cl, fuc, glc, mg, na, zn
          1. region l:91-140 [128097] picpiclink
        29. 1pfx picpicxrefxref
          complexed with doh
          1. region l:47-86 [44207] picpiclink
          2. region l:87-146 [44208] picpiclink
        30. 1x7a picpicxref
          automatically matched to d1pfxl1
          complexed with 187
          1. region l:50-86 [121782] picpiclink
        31. 1x7a picpicxref
          automatically matched to d1pfxl2
          complexed with 187
          1. region l:87-146 [121783] picpiclink
    2. Coagulation factor VIIa [57201]
      1. Human (Homo sapiens) [TaxId: 9606] [57202] (19)
        SQ P08709 108-202 ! SQ P08709 107-202
        1. 2bz6 picpicxref
          automatically matched to d1klil_
          complexed with 346, ca, so4
          1. region l:90-142 [129553] picpiclink
        2. 1w7x picpicxref
          automatically matched to d1klil_
          complexed with 413, ca, gol, so4
          1. region l:90-143 [120700] picpiclink
        3. 1kli picpicxref
          C-terminal domain
          complexed with ben, ca, gol, so4
          1. chain l [77436] picpiclink
        4. 1ygc picpicxref
          automatically matched to d1klil_
          complexed with 905, ca, so4
          1. region l:90-142 [123143] picpiclink
        5. 1jbu picpicxref
          complexed with ben, so4
          1. chain l [62857] picpiclink
        6. 1dan picpicxrefxrefxref
          complexed with ca, cac, ch2, cl, fuc, glc
          1. region l:49-86 [44209] picpiclink
          2. region l:87-142 [44210] picpiclink
        7. 1cvw picpicxref
          complexed with ans, ca
          1. chain l [44211] picpiclink
        8. 1o5d picpicxrefxref
          complexed with cr9; mutant
          1. region l:47-86 [103881] picpiclink
          2. region l:87-142 [103882] picpiclink
        9. 1fak picpicxrefxrefxrefxref
          1. region l:49-86 [44212] picpiclink
          2. region l:87-143 [44213] picpiclink
        10. 1klj picpicxref
          C-terminal domain
          complexed with ca, egl
          1. chain l [77438] picpiclink
        11. 1w8b picpicxref
          automatically matched to d1klil_
          complexed with 413, ca
          1. region l:88-143 [120717] picpiclink
        12. 1qfk picpicxref
          complexed with ca, ch2, fuc, glc, nag
          1. region l:49-86 [44214] picpiclink
          2. region l:87-144 [44215] picpiclink
        13. 1j9c picpicxrefxref
          complexed with ca, fuc, glc, nag
          1. region l:48-86 [103842] picpiclink
          2. region l:87-142 [103843] picpiclink
        14. 1dva picpicxref
          complexed with ace, ca, cac, ch2, fuc, gal, glc
          1. region l:42-86 [44216] picpiclink
          2. region l:87-142 [44217] picpiclink
          3. region m:42-86 [44218] picpiclink
          4. region m:87-142 [44219] picpiclink
        15. 1bf9 picpic
          N-terminal domain
          1. chain a [44223] picpiclink
        16. 1f7e picpic
          N-terminal domain
          1. chain a [44221] picpiclink
        17. 1ff7 picpic
          N-terminal domain
          complexed with fuc
          1. chain a [44222] picpiclink
        18. 1f7m picpic
          N-terminal domain
          1. chain a [44224] picpiclink
        19. 1ffm picpic
          N-terminal domain
          complexed with fuc
          1. chain a [44220] picpiclink
    3. E-selectin, EGF-domain [57203]
      1. Human (Homo sapiens) [TaxId: 9606] [57204] (5)
        1. 1g1t picpicxref
          complexed with 1na, ca, fuc, gal, sia
          1. region a:119-157 [65105] picpiclink
        2. 1g1s picpicxref
          complexed with fuc, gal, mpd, na, nag, nga, sia, sr
          1. region a:119-158 [65101] picpiclink
          2. region b:119-157 [65103] picpiclink
        3. 1esl picpicxref
          complexed with ca, cl
          1. region a:119-157 [44225] picpiclink
        4. 1g1q picpicxref
          complexed with ca, mpd
          1. region a:119-160 [65085] picpiclink
          2. region b:119-160 [65087] picpiclink
          3. region c:119-159 [65089] picpiclink
          4. region d:119-160 [65091] picpiclink
        5. 1g1r picpicxref
          complexed with 1na, ca, fuc, gal, mpd, sia
          1. region a:119-160 [65093] picpiclink
          2. region b:119-160 [65095] picpiclink
          3. region c:119-159 [65097] picpiclink
          4. region d:119-160 [65099] picpiclink
    4. Factor X, N-terminal module [57205]
      1. Human (Homo sapiens) [TaxId: 9606] [57206] (75)
        SQ P00742 127-178
        1. 2p3u picpicxref
          automatically matched to d1g2lb_
          complexed with 663, ca
          1. region a:87-137 [149188] picpiclink
        2. 2uwp picpicxref
          automatically matched to d1g2lb_
          complexed with 894, ca, mg
          1. region b:-2-49 [140001] picpiclink
        3. 2bok picpicxref
          automatically matched to d1g2lb_
          complexed with 784, na; mutant
          1. region l:87-138 [128917] picpiclink
        4. 2uwo picpicxref
          automatically matched to d1g2lb_
          complexed with 701
          1. region b:-2-49 [139999] picpiclink
        5. 2j4i picpicxref
          automatically matched to d1g2lb_
          complexed with ca, gsj
          1. region b:-1-49 [138004] picpiclink
        6. 2pr3 picpicxref
          automatically matched to d1g2lb_
          complexed with 237, ca
          1. region b:1-50 [149798] picpiclink
        7. 3cen picpicxref
          automatically matched to d1g2lb_
          complexed with fxa
          1. region l:87-138 [156531] picpiclink
        8. 2j2u picpicxref
          automatically matched to d1g2lb_
          complexed with gsq
          1. region b:-1-49 [137973] picpiclink
        9. 2p3t picpicxref
          automatically matched to d1g2lb_
          complexed with 993, ca, cl
          1. region a:87-138 [149186] picpiclink
        10. 2j34 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, gs6
          1. region b:-1-50 [137977] picpiclink
        11. 1z6e picpicxref
          automatically matched to d1g2lb_
          complexed with ik8
          1. region b:87-138 [124519] picpiclink
        12. 2j95 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, gsx
          1. region b:-1-50 [138148] picpiclink
        13. 2uwl picpicxref
          automatically matched to d1g2lb_
          complexed with 895
          1. region b:-2-49 [139991] picpiclink
        14. 1g2l picpicxref
          complexed with ca, t87
          1. chain b [65113] picpiclink
        15. 2j94 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, g15
          1. region b:-2-49 [138146] picpiclink
        16. 2q1j picpicxref
          automatically matched to d1g2lb_
          complexed with ca, fxi
          1. region b:0-50 [149997] picpiclink
        17. 1fjs picpicxref
          complexed with ca, cl, gol, z34
          1. chain l [44226] picpiclink
        18. 2cji picpicxref
          automatically matched to d1g2lb_
          complexed with ca, gsk
          1. region b:-1-50 [130539] picpiclink
        19. 2p93 picpicxref
          automatically matched to d1g2lb_
          complexed with me1
          1. region l:87-138 [149323] picpiclink
        20. 1lpg picpicxref
          complexed with ca, ima
          1. chain a [84666] picpiclink
        21. 1mq5 picpicxref
          complexed with ca, gol, xlc
          1. chain l [79401] picpiclink
        22. 2ei8 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, dt8
          1. region b:85-138 [146867] picpiclink
        23. 2p94 picpicxref
          automatically matched to d1g2lb_
          complexed with me4
          1. region l:87-138 [149325] picpiclink
        24. 2j38 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, gs5
          1. region b:-1-49 [137980] picpiclink
        25. 3cs7 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, lg0
          1. region l:87-138 [156957] picpiclink
        26. 1mq6 picpicxref
          complexed with ca, gol, xld
          1. chain l [79403] picpiclink
        27. 2d1j picpicxref
          automatically matched to d1g2lb_
          complexed with ca, d01
          1. region b:85-138 [131128] picpiclink
        28. 2boh picpicxref
          automatically matched to d1g2lb_
          complexed with ca, iia
          1. region a:-3-51 [128910] picpiclink
        29. 2bq7 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, iid
          1. region a:-2-49 [128963] picpiclink
        30. 2p16 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, gg2
          1. region l:87-138 [149155] picpiclink
        31. 1nfy picpicxref
          complexed with ca, rtr
          1. chain b [80474] picpiclink
        32. 2p95 picpicxref
          automatically matched to d1g2lb_
          complexed with me5
          1. region l:87-138 [149327] picpiclink
        33. 1v3x picpicxref
          complexed with ca, d76
          1. chain b [113507] picpiclink
        34. 1kye picpicxref
          complexed with ca, rup
          1. chain b [77630] picpiclink
        35. 2fzz picpicxref
          automatically matched to d1g2lb_
          complexed with 5qc
          1. region l:87-138 [134487] picpiclink
        36. 1nfu picpicxref
          complexed with ca, rrp
          1. chain b [80468] picpiclink
        37. 1nfw picpicxref
          complexed with ca, rrr
          1. chain b [80470] picpiclink
        38. 1f0r picpicxref
          complexed with 815, ca
          1. chain b [44227] picpiclink
        39. 1nfx picpicxref
          complexed with ca, rdr
          1. chain b [80472] picpiclink
        40. 1c5m picpicxref
          1. chain f [44228] picpiclink
        41. 1f0s picpicxref
          complexed with ca, pr2
          1. chain b [44229] picpiclink
        42. 1lpk picpicxref
          complexed with ca, cbb
          1. chain a [84668] picpiclink
        43. 2ei6 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, d92
          1. region b:85-138 [146863] picpiclink
        44. 1wu1 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, d91
          1. region b:85-138 [121271] picpiclink
        45. 2g00 picpicxref
          automatically matched to d1g2lb_
          complexed with 4qc
          1. region l:87-138 [134489] picpiclink
        46. 2ei7 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, d93
          1. region b:85-138 [146865] picpiclink
        47. 2h9e picpicxrefxref
          automatically matched to d1g2lb_
          complexed with act, lpd, na, po4
          1. region l:89-136 [136256] picpiclink
        48. 1ezq picpicxref
          complexed with ca, rpr
          1. chain b [44230] picpiclink
        49. 1hcg picpicxref
          1. chain b [44231] picpiclink
        50. 1iqg picpicxref
          complexed with ca, xme
          1. chain l [90675] picpiclink
        51. 2bmg picpicxref
          automatically matched to d1g2lb_
          complexed with ca, i1h
          1. region a:-2-50 [128795] picpiclink
        52. 1ksn picpicxref
          complexed with ca, fxv
          1. chain b [72925] picpiclink
        53. 1lpz picpicxref
          complexed with ca, cmb
          1. chain a [84670] picpiclink
        54. 1iqn picpicxref
          complexed with ca, xmc
          1. chain l [90689] picpiclink
        55. 2phb picpicxref
          automatically matched to d1g2lb_
          complexed with 230, ca
          1. region b:0-50 [149465] picpiclink
        56. 1lqd picpicxref
          complexed with ca, cmi
          1. chain a [84676] picpiclink
        57. 1iqm picpicxref
          complexed with ca, xmk
          1. chain l [90687] picpiclink
        58. 2bqw picpicxref
          automatically matched to d1g2lb_
          complexed with ca, iie
          1. region a:-2-49 [128971] picpiclink
        59. 1g2m picpicxref
          complexed with ca, r11
          1. chain b [65115] picpiclink
        60. 1fax picpicxref
          complexed with ca, dx9; mutant
          1. chain l [44238] picpiclink
        61. 1xkb picpicxref
          complexed with 4pp, ca, doh
          1. region a:48-86 [44232] picpiclink
          2. region a:87-138 [44233] picpiclink
          3. region b:50-86 [44234] picpiclink
          4. region b:87-139 [44235] picpiclink
        62. 1iql picpicxref
          complexed with ca, xmj
          1. chain l [90685] picpiclink
        63. 1xka picpicxref
          complexed with 4pp, ca, doh
          1. region l:49-86 [44236] picpiclink
          2. region l:87-139 [44237] picpiclink
        64. 1p0s picpicxrefxrefxref
          complexed with mg, na; mutant
          1. region l:87-138 [93874] picpiclink
        65. 1iqh picpicxref
          complexed with ca, xmf
          1. chain l [90677] picpiclink
        66. 2bq6 picpicxref
          automatically matched to d1g2lb_
          complexed with ca, iib
          1. region a:1a-49 [128961] picpiclink
        67. 1iqi picpicxref
          complexed with ca, xmg
          1. chain l [90679] picpiclink
        68. 1ioe picpicxref
          complexed with ca, xma
          1. chain l [90668] picpiclink
        69. 1iqj picpicxref
          complexed with ca, xmh
          1. chain l [90681] picpiclink
        70. 1iqk picpicxref
          complexed with ca, xmi
          1. chain l [90683] picpiclink
        71. 1iqf picpicxref
          complexed with ca, xmd
          1. chain l [90673] picpiclink
        72. 2p3f picpicxref
          automatically matched to d1g2lb_
          complexed with na
          1. region l:88-138 [149176] picpiclink
        73. 1iqe picpicxref
          complexed with ca, xmb
          1. chain l [90671] picpiclink
        74. 2gd4 picpicxrefxrefxrefxref
          automatically matched to d1g2lb_
          complexed with bma, ca, man, nag, nto; mutant
          1. region a:87-138 [135004] picpiclink
        75. 2gd4 picpicxrefxrefxrefxref
          automatically matched to d1g2lb_
          complexed with bma, ca, man, nag, nto; mutant
          1. region l:87-138 [135005] picpiclink
      2. Cow (Bos taurus) [TaxId: 9913] [57207] (5)
        1. 1kig picpicxrefxref
          1. chain l [44239] picpiclink
        2. 1ccf picpic
          complexed with hyd
          1. chain a [44241] picpiclink
        3. 1apo picpic
          complexed with oh
          1. chain a [44240] picpiclink
        4. 1whe picpicxref
          complexed with doh
          1. region a:47-86 [44242] picpiclink
        5. 1whf picpicxref
          complexed with doh
          1. region a:47-86 [44243] picpiclink
    5. Activated protein c (autoprothrombin IIa) [57208]
      1. Human (Homo sapiens) [TaxId: 9606] [57209] (1)
        1. 1aut picpicxref
          complexed with mai
          1. region l:49-96 [44244] picpiclink
          2. region l:97-146 [44245] picpiclink
    6. Prostaglandin H2 synthase-1, EGF-like module [57210]
      the rest of protein is heme-linked peroxidase, all-alpha fold
      1. Sheep (Ovis aries) [TaxId: 9940] [57211] (22)
        SQ P05979 32-584
        1. 1q4g picpicxref
          complexed with bfl, bog, gol, hem, man, nag
          1. region a:32-73 [95790] picpiclink
          2. region b:32-73 [95792] picpiclink
        2. 2ayl picpicxrefxref
          automatically matched to d1cqeb2
          complexed with bog, flp, gol, man, mnh, nag
          1. region a:32-73 [127560] picpiclink
        3. 2ayl picpicxrefxref
          automatically matched to d1cqeb2
          complexed with bog, flp, gol, man, mnh, nag
          1. region b:1032-1073 [127562] picpiclink
        4. 1eqh picpicxref
          complexed with bog, flp, hem, nag
          1. region a:33-73 [59492] picpiclink
          2. region b:33-73 [59494] picpiclink
        5. 1eqg picpicxref
          complexed with bog, hem, ibp, nag
          1. region a:33-73 [59488] picpiclink
          2. region b:33-73 [59490] picpiclink
        6. 1ht8 picpicxref
          complexed with 34c, bog, hem, nag
          1. region a:33-73 [61249] picpiclink
          2. region b:33-73 [61251] picpiclink
        7. 1ht5 picpicxref
          complexed with bog, fl2, hem, nag
          1. region a:33-73 [61245] picpiclink
          2. region b:33-73 [61247] picpiclink
        8. 1cqe picpicxref
          complexed with bog, flp, hem, nag
          1. region a:32-73 [44246] picpiclink
          2. region b:31-73 [44247] picpiclink
        9. 1diy picpicxref
          complexed with acd, bma, bog, coh, nag
          1. region a:32-73 [44249] picpiclink
        10. 2oyu picpicxref
          automatically matched to d1cqeb2
          complexed with bma, bog, hem, ims, nag
          1. region p:32-73 [149081] picpiclink
        11. 1ebv picpicxref
          complexed with hem, nag, scl
          1. region a:33-73 [44252] picpiclink
        12. 1pth picpicxrefxref
          complexed with bog, brm, hem, nag, sal
          1. region a:33-73 [44248] picpiclink
        13. 1pth picpicxrefxref
          duplicate of 1PTH 33-73
          complexed with bog, brm, hem, nag, sal
          1. region b:33-73 [118583] picpiclink
        14. 1pge picpicxref
          complexed with bog, hem, isf, nag
          1. region a:33-73 [44250] picpiclink
          2. region b:33-73 [44251] picpiclink
        15. 1igz picpicxref
          complexed with bma, bog, coh, eic, glc, nag
          1. region a:32-73 [66139] picpiclink
        16. 1fe2 picpicxref
          complexed with bma, bog, coh, lax, nag
          1. region a:32-73 [59779] picpiclink
        17. 2oye picpicxref
          automatically matched to d1cqeb2
          complexed with bma, bog, flc, hem, im8, nag, ndg
          1. region p:32-73 [149066] picpiclink
        18. 1igx picpicxref
          complexed with bma, bog, coh, epa, glc, nag
          1. region a:32-73 [66137] picpiclink
        19. 1u67 picpicxref
          complexed with acd, bma, bog, coh, nag; mutant
          1. region a:32-73 [107698] picpiclink
        20. 1prh picpicxref
          complexed with hem
          1. region a:33-73 [44253] picpiclink
          2. region b:33-73 [44254] picpiclink
        21. 1pgf picpicxref
          complexed with hem, imm, nag
          1. region a:33-73 [44257] picpiclink
          2. region b:33-73 [44258] picpiclink
        22. 1pgg picpicxref
          complexed with hem, imm, nag
          1. region a:33-73 [44255] picpiclink
          2. region b:33-73 [44256] picpiclink
      2. Mouse (Mus musculus) [TaxId: 10090] [57212] (8)
        1. 1cvu picpicxref
          complexed with acd, bog, man, nag; mutant
          1. region a:33-73 [44259] picpiclink
          2. region b:2033-2073 [44260] picpiclink
        2. 3pgh picpicxref
          complexed with flp, hem, nag
          1. region a:33-73 [44269] picpiclink
          2. region b:33-73 [44270] picpiclink
          3. region c:33-73 [44271] picpiclink
          4. region d:33-73 [44272] picpiclink
        3. 4cox picpicxref
          complexed with hem, imn, nag
          1. region a:33-73 [44265] picpiclink
          2. region b:33-73 [44266] picpiclink
          3. region c:33-73 [44267] picpiclink
          4. region d:33-73 [44268] picpiclink
        4. 6cox picpicxref
          complexed with hem, nag, s58
          1. region a:33-73 [44273] picpiclink
          2. region b:33-73 [44274] picpiclink
        5. 1cx2 picpicxref
          complexed with hem, nag, s58
          1. region a:33-73 [44261] picpiclink
          2. region b:33-73 [44262] picpiclink
          3. region c:33-73 [44263] picpiclink
          4. region d:33-73 [44264] picpiclink
        6. 1pxx picpicxref
          complexed with bog, dif, hem, nag
          1. region a:33-73 [95308] picpiclink
          2. region b:1033-1073 [95310] picpiclink
          3. region c:2033-2073 [95312] picpiclink
          4. region d:3033-3073 [95314] picpiclink
        7. 5cox picpicxref
          complexed with hem, nag
          1. region a:33-73 [44279] picpiclink
          2. region b:33-73 [44280] picpiclink
          3. region c:33-73 [44281] picpiclink
          4. region d:33-73 [44282] picpiclink
        8. 1ddx picpicxref
          complexed with bog, nag, pgx
          1. region a:33-73 [44275] picpiclink
          2. region b:1033-1073 [44276] picpiclink
          3. region c:2033-2073 [44277] picpiclink
          4. region d:3033-3073 [44278] picpiclink
    7. P-selectin, EGF-domain [57213]
      1. Human (Homo sapiens) [TaxId: 9606] [57214] (1)
        1. 1fsb picpic
          1. chain a [44283] picpiclink
    8. Epidermal growth factor, EGF [57215]
      1. Mouse (Mus musculus) [TaxId: 10090] [57216] (8)
        1. 3egf picpic
          1. chain a [44285] picpiclink
        2. 1egf picpic
          1. chain a [44290] picpiclink
        3. 1eph picpic
          1. chain a [44287] picpiclink
        4. 1a3p picpic
          complexed with aba; mutant
          1. chain a [44284] picpiclink
        5. 1epg picpic
          1. chain a [44286] picpiclink
        6. 1epj picpic
          1. chain a [44289] picpiclink
        7. 1epi picpic
          1. chain a [44288] picpiclink
        8. 1gk5 picpic
          EGF/TGFalpha chimera
          1. chain a [70209] picpiclink
      2. Human (Homo sapiens) [TaxId: 9606] [69939] (4)
        1. 1nql picpicxrefxref
          complexed with EGF receptor
          complexed with aso, nag
          1. chain b [86037] picpiclink
        2. 1jl9 picpic
          1. chain a [66831] picpiclink
          2. chain b [66832] picpiclink
        3. 1ivo picpicxrefxref
          complexed with EGF receptor
          complexed with nag
          1. chain c [76853] picpiclink
          2. chain d [76854] picpiclink
        4. 1p9j picpic
          EGF/TGFalpha chimera
          1. chain a [94391] picpiclink
    9. Transforming growth factor alpha [57217]
      1. Human (Homo sapiens) [TaxId: 9606] [57218] (6)
        1. 1mox picpicxrefxref
          complexed with EGF receptor
          complexed with cd, cl, fuc, man, nag, pt
          1. chain c [91380] picpiclink
          2. chain d [91381] picpiclink
        2. 3tgf picpic
          1. chain a [44292] picpiclink
        3. 1yug picpic
          1. chain a [44293] picpiclink
        4. 2tgf picpic
          1. chain a [44291] picpiclink
        5. 4tgf picpic
          1. chain a [44294] picpiclink
        6. 1yuf picpic
          1. chain a [44295] picpiclink
    10. Epiregulin, EGF-domain [103561]
      1. Human (Homo sapiens) [TaxId: 9606] [103562] (2)
        1. 1k36 picpic
          1. chain a [90931] picpiclink
        2. 1k37 picpic
          1. chain a [90932] picpiclink
    11. Betacellulin-2 [75670]
      1. Human (Homo sapiens) [TaxId: 9606] [75671] (2)
        1. 1iox picpic
          1. chain a [71252] picpiclink
        2. 1ip0 picpic
          1. chain a [71253] picpiclink
    12. Heparin-binding epidermal growth factor, HBEGF [57219]
      extracellular domain
      1. Human (Homo sapiens) [TaxId: 9606] [57220] (1)
        1. 1xdt picpicxrefxrefxref
          1. chain r [44296] picpiclink
    13. Plasminogen activator (urokinase-type) [57221]
      1. Human (Homo sapiens) [TaxId: 9606] [57222] (12)
        1. 2i9a picpicxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with po4
          1. region a:10-49 [137110] picpiclink
        2. 2i9a picpicxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with po4
          1. region b:10-49 [137112] picpiclink
        3. 2i9a picpicxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with po4
          1. region c:11-49 [137114] picpiclink
        4. 2i9a picpicxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with po4
          1. region d:10-49 [137116] picpiclink
        5. 2fd6 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with edo, etx, fuc, nag, pg4, pge, so4
          1. region a:11-49 [133293] picpiclink
        6. 3bt2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1urka1
          complexed with nag
          1. region a:9-49 [155540] picpiclink
        7. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with bma, nag, so4; mutant
          1. region a:11-49 [137118] picpiclink
        8. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with bma, nag, so4; mutant
          1. region b:11-49 [137120] picpiclink
        9. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with bma, nag, so4; mutant
          1. region c:11-49 [137122] picpiclink
        10. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1urk_1
          complexed with bma, nag, so4; mutant
          1. region d:11-49 [137124] picpiclink
        11. 3bt1 picpicxrefxrefxrefxrefxref
          automatically matched to d1urka1
          complexed with man, nag
          1. region a:8-49 [155534] picpiclink
        12. 1urk picpicxref
          complexed with fuc
          1. region a:6-49 [44297] picpiclink
    14. Heregulin-alpha, EGF-like domain [57223]
      1. Human (Homo sapiens) [TaxId: 9606] [57224] (4)
        1. 1hae picpic
          1. chain a [44298] picpiclink
        2. 1haf picpic
          1. chain a [44299] picpiclink
        3. 1hrf picpic
          1. chain a [44301] picpiclink
        4. 1hre picpic
          1. chain a [44300] picpiclink
    15. Thrombomodulin, different EGF-like domains [57225]
      1. Human (Homo sapiens) [TaxId: 9606] [57226] (6)
        1. 1dx5 picpicxref
          complexed with ca, fmt, na, nag; mutant
          1. region i:345-387 [44302] picpiclink
          2. region i:388-422 [44303] picpiclink
          3. region i:423-462 [44304] picpiclink
          4. region j:345-387 [44305] picpiclink
          5. region j:388-422 [44306] picpiclink
          6. region j:423-462 [44307] picpiclink
          7. region k:345-387 [44308] picpiclink
          8. region k:388-422 [44309] picpiclink
          9. region k:423-462 [44310] picpiclink
          10. region l:345-387 [44311] picpiclink
          11. region l:388-422 [44312] picpiclink
          12. region l:423-462 [44313] picpiclink
        2. 1zaq picpic
          1. chain a [44314] picpiclink
        3. 1tmr picpic
          mutant
          1. chain a [44316] picpiclink
        4. 1adx picpic
          1. chain a [44315] picpiclink
        5. 1dqb picpic
          complexed with nag
          1. region a:1-44 [44318] picpiclink
          2. region a:45-83 [44319] picpiclink
        6. 2adx picpic
          1. chain a [44317] picpiclink
    16. Fibrillin-1 [57227]
      duplication: contains 47 EFG-like domains
      1. Human (Homo sapiens) [TaxId: 9606] [57228] (8)
        1. 1uzk picpicxref
          automatically matched to d1uzja1
          complexed with ca
          1. region a:1486-1528 [119806] picpiclink
        2. 1uzk picpicxref
          automatically matched to d1uzja2
          complexed with ca
          1. region a:1605-1647 [119807] picpiclink
        3. 1uzp picpicxref
          CBEGF22 and CBEGF23
          complexed with sm
          1. region a:1486-1528 [100232] picpiclink
          2. region a:1605-1647 [100233] picpiclink
        4. 1uzj picpicxref
          CBEGF22 and CBEGF23
          complexed with ca
          1. region a:1486-1528 [100223] picpiclink
          2. region a:1605-1647 [100224] picpiclink
          3. region b:2486-2528 [100226] picpiclink
          4. region b:2605-2647 [100227] picpiclink
          5. region c:3486-3528 [100229] picpiclink
          6. region c:3605-3647 [100230] picpiclink
        5. 1uzq picpicxref
          CBEGF22 and CBEGF23
          1. region a:1486-1528 [100235] picpiclink
          2. region a:1605-1647 [100236] picpiclink
        6. 1emo picpic
          39th and 40th calcium-binding EGF-like domains
          complexed with ca
          1. region a:2124-2166 [44320] picpiclink
          2. region a:2167-2205 [44321] picpiclink
        7. 1emn picpic
          39th and 40th calcium-binding EGF-like domains
          complexed with ca
          1. region a:2124-2166 [44322] picpiclink
          2. region a:2167-2205 [44323] picpiclink
        8. 1lmj picpic
          12th and 13th calcium-binding EGF-like domains
          complexed with ca
          1. region a:3-46 [84631] picpiclink
          2. region a:47-88 [84632] picpiclink
    17. Mannose-binding protein associated serine protease 2, MASP2 [90141]
      EGF-like domain separates two CUB domains
      1. Rat (Rattus norvegicus) [TaxId: 10116] [90142] (1)
        1. 1nt0 picpicxref
          complexed with ahb, ca, edo, nag
          1. region a:120-164 [86145] picpiclink
          2. region g:120-164 [86148] picpiclink
      2. Human (Homo sapiens) [TaxId: 9606] [111402] (1)
        SQ O00187 17-181
        1. 1szb picpicxref
          complexed with ca
          1. region a:124-168 [106146] picpiclink
          2. region b:124-168 [106148] picpiclink
    18. Complement C1S component [90143]
      1. Human (Homo sapiens) [TaxId: 9606] [90144] (1)
        1. 1nzi picpicxref
          complexed with ca, mg
          1. region a:118-159 [86450] picpiclink
          2. region b:118-159 [86452] picpiclink
    19. Complement protease C1R [57229]
      1. Human (Homo sapiens) [TaxId: 9606] [57230] (1)
        1. 1apq picpic
          1. chain a [44324] picpiclink
    20. Plasminogen activator (tissue-type), t-PA [57231]
      1. Human (Homo sapiens) [TaxId: 9606] [57232] (1)
        1. 1tpg picpicxref
          mutant
          1. region a:51-91 [44325] picpiclink
    21. Low density lipoprotein (LDL) receptor, different EGF domains [64539]
      1. Human (Homo sapiens) [TaxId: 9606] [64540] (7)
        SQ P01130 272-353
        1. 1ijq picpicxref
          1. region a:643-692 [62507] picpiclink
          2. region b:643-692 [62509] picpiclink
        2. 3bps picpic
          automatically matched to d1hj7a1
          complexed with ca
          1. region e:293-332 [155489] picpiclink
        3. 1i0u picpic
          complexed with ca
          1. region a:1-41 [61493] picpiclink
          2. region a:42-82 [61494] picpiclink
        4. 1hz8 picpic
          complexed with ca
          1. region a:1-41 [61432] picpiclink
          2. region a:42-82 [61433] picpiclink
        5. 1hj7 picpic
          complexed with ca
          1. region a:293-333 [61071] picpiclink
          2. region a:334-372 [61072] picpiclink
        6. 1xfe picpicxref
          complexed with ca
          1. region a:45-83 [115259] picpiclink
        7. 1n7d picpicxrefxref
          modules A, B, and C in the whole receptor structure context
          complexed with ca, keg, man, nag; mutant
          1. region a:296-332 [80237] picpiclink
          2. region a:333-376 [80238] picpiclink
          3. region a:643-693 [80239] picpiclink
    22. Neurogenic locus notch homolog protein 1, Notch1 [118243]
      1. Human (Homo sapiens) [TaxId: 9606] [118244] (4)
        SQ P46531 411-526
        1. 2vj3 picpic
          automatically matched to d1toza1
          complexed with ca, cl, na
          1. region a:411-452 [153180] picpiclink
        2. 2vj3 picpic
          automatically matched to d1toza2
          complexed with ca, cl, na
          1. region a:453-491 [153181] picpiclink
        3. 2vj3 picpic
          automatically matched to d1toza3
          complexed with ca, cl, na
          1. region a:492-526 [153182] picpiclink
        4. 1toz picpic
          mutant
          1. region a:411-452 [112605] picpiclink
          2. region a:453-491 [112606] picpiclink
          3. region a:492-526 [112607] picpiclink
  2. Integrin beta EGF-like domains [69940] (1)
    1. Integrin beta EGF-like domains [69941]
      1. Human (Homo sapiens) [TaxId: 9606] [69942] (5)
        SQ P05106 27-716
        1. 1m1x picpicxrefxrefxrefxrefxref
          complexed with mn, nag
          1. region b:532-562 [74429] picpiclink
          2. region b:563-605 [74430] picpiclink
        2. 1jv2 picpicxrefxrefxrefxrefxref
          complexed with ca, nag
          1. region b:532-562 [67341] picpiclink
          2. region b:563-605 [67342] picpiclink
        3. 1l5g picpicxrefxrefxrefxrefxref
          complexed with mn, mva, nag
          1. region b:532-562 [73588] picpiclink
          2. region b:563-605 [73589] picpiclink
        4. 1u8c picpicxrefxrefxrefxrefxrefxref
          complexed with ca, nag
          1. region b:1532-1562 [113123] picpiclink
          2. region b:1563-1605 [113124] picpiclink
        5. 1l3y picpic
          EGF-like module 3
          1. chain a [73558] picpiclink
  3. EGF-like domain of nidogen-1 [64541] (1)
    1. EGF-like domain of nidogen-1 [64542]
      1. Mouse (Mus musculus) [TaxId: 10090] [64543] (2)
        1. 1gl4 picpicxrefxref
          complexed with epe, zn
          1. region a:359-398 [65287] picpiclink
        2. 1h4u picpicxref
          partly disordered
          mutant
          1. region a:367-398 [60623] picpiclink
  4. Laminin-type module [57233] (1)
    1. Laminin gamma1 chain [57234]
      1. Mouse (Mus musculus) [TaxId: 10090] [57235] (3)
        1. 1klo picpic
          1. region a:11-65 [44326] picpiclink
          2. region a:66-121 [44327] picpiclink
          3. region a:122-172 [44328] picpiclink
        2. 1npe picpicxref
          complexed with cd
          1. region b:736-792 [92033] picpiclink
          2. region b:793-848 [92034] picpiclink
          3. region b:849-899 [92035] picpiclink
        3. 1tle picpic
          1. chain a [44329] picpiclink
  5. Follistatin (FS) module N-terminal domain, FS-N [57236] (2)
    1. Domain of BM-40/SPARC/osteonectin [57237]
      the N-terminal part of FS module
      1. Human (Homo sapiens) [TaxId: 9606] [57238] (2)
        1. 1nub picpicxrefxref
          complexed with ca, nag; mutant
          1. region a:53-77 [44330] picpiclink
          2. region b:53-77 [44331] picpiclink
        2. 1bmo picpicxrefxref
          complexed with ca, nag
          1. region a:54-77 [44332] picpiclink
          2. region b:54-77 [44333] picpiclink
    2. Domain of follistatin [90145]
      the N-terminal part of the heparin-binding module, FS1
      1. Rat (Rattus norvegicus) [TaxId: 10116] [90146] (3)
        1. 1lr7 picpicxref
          complexed with so4
          1. region a:64-88 [84679] picpiclink
        2. 1lr8 picpicxref
          complexed with ihs
          1. region a:64-88 [84681] picpiclink
        3. 1lr9 picpicxref
          1. region a:64-88 [84683] picpiclink
  6. Merozoite surface protein 1 (MSP-1) [57239] (3)
    1. Merozoite surface protein 1 (MSP-1) [57240]
      1. Malaria parasite (Plasmodium cynomolgi) [TaxId: 5827] [57241] (1)
        1. 1b9w picpic
          1. region a:1-45 [44334] picpiclink
          2. region a:46-89 [44335] picpiclink
      2. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [57242] (3)
        1. 1ob1 picpicxrefxrefxrefxref
          complexed with cac
          1. region c:1-45 [86752] picpiclink
          2. region c:46-96 [86753] picpiclink
          3. region f:1-45 [86758] picpiclink
          4. region f:46-97 [86759] picpiclink
        2. 2flg picpic
          automatically matched to d1ceja1
          complexed with nh2
          1. region a:1-45 [133713] picpiclink
        3. 1cej picpic
          1. region a:1-45 [44336] picpiclink
          2. region a:46-96 [44337] picpiclink
      3. Malaria parasite (Plasmodium knowlesi) [TaxId: 5850] [82892] (1)
        1. 1n1i picpic
          complexed with his, imd
          1. region a:8-51 [79805] picpiclink
          2. region a:52-98 [79806] picpiclink
          3. region b:8-51 [79807] picpiclink
          4. region b:52-100 [79808] picpiclink
          5. region c:9-51 [79809] picpiclink
          6. region c:52-101 [79810] picpiclink
          7. region d:8-51 [79811] picpiclink
          8. region d:52-94 [79812] picpiclink
  7. Cripto EGF-like domain-like [144100] (1)
    1. Cripto growth factor [144101]
      Teratocarcinoma-derived growth factor
      1. Mouse (Mus musculus) [TaxId: 10090] [144102] (1)
        SQ P51865 96-134
        1. 2j5h picpic
          complexed with ace, nh2
          1. region a:1-39 [138036] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk