Structural Classification of Proteins
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Family: UBC-related

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: UBC-like [54494]
    alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
  4. Superfamily: UBC-like [54495]
    link to SUPERFAMILY database - Superfamily
  5. Family: UBC-related [54496]

Protein Domains:

  1. Ubiquitin conjugating enzyme, UBC [54497]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [54498] (1)
      1. 2aak picpic
        1. chain a [38325] picpiclink
    2. Baker's yeast (Saccharomyces cerevisiae), ubc1 [TaxId: 4932] [69685] (3)
      SQ P21734
      1. 1fzy picpic
        1. chain a [65072] picpiclink
        2. chain b [65073] picpiclink
      2. 1fxt picpicxref
        1. chain a [65055] picpiclink
      3. 1tte picpicxref
        mutant
        1. region a:2-160 [107296] picpiclink
    3. Baker's yeast (Saccharomyces cerevisiae), ubc2 (RAD6) [TaxId: 4932] [54499] (1)
      1. 1ayz picpic
        1. chain a [38326] picpiclink
        2. chain b [38327] picpiclink
        3. chain c [38328] picpiclink
    4. Baker's yeast (Saccharomyces cerevisiae), ubc4 [TaxId: 4932] [54500] (1)
      1. 1qcq picpic
        1. chain a [38329] picpiclink
    5. Baker's yeast (Saccharomyces cerevisiae), ubc7 [TaxId: 4932] [54501] (1)
      1. 2ucz picpic
        1. chain a [38330] picpiclink
    6. Baker's yeast (Saccharomyces cerevisiae), ubc13 [TaxId: 4932] [64239] (3)
      1. 1jat picpicxref
        complexed with Mms2
        1. chain a [62818] picpiclink
      2. 1jbb picpic
        1. chain a [62842] picpiclink
        2. chain b [62843] picpiclink
      3. 2gmi picpicxrefxref
        mutant
        1. region a:1-152 [145218] picpiclink
    7. Baker's yeast (Saccharomyces cerevisiae), mms2 [TaxId: 4932] [64241] (2)
      1. 1jat picpicxref
        complexed with ubc13
        1. chain b [62819] picpiclink
      2. 2gmi picpicxrefxref
        automatically matched to d1jatb_
        mutant
        1. region b:3-137 [135381] picpiclink
    8. Human (Homo sapiens), ubc13 [TaxId: 9606] [64240] (5)
      1. 1j7d picpicxref
        complexed with Mms2
        1. chain b [62681] picpiclink
      2. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1j7db_
        1. region b:6-154 [129686] picpiclink
      3. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1j7db_
        1. region e:6-154 [129688] picpiclink
      4. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1j7db_
        1. region h:6-154 [129690] picpiclink
      5. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1j7db_
        1. region k:6-154 [129692] picpiclink
    9. Human (Homo sapiens), mms2 [TaxId: 9606] [64242] (3)
      1. 1j74 picpic
        1. chain a [62672] picpiclink
      2. 1j7d picpicxref
        complexed with ubc13
        1. chain a [62680] picpiclink
      3. 1zgu picpicxref
        automatically matched to d1j7da_
        mutant
        1. region a:12-150 [125061] picpiclink
    10. Human (Homo sapiens), ubch7 [TaxId: 9606] [54502] (2)
      1. 1c4z picpicxref
        1. chain d [38331] picpiclink
      2. 1fbv picpicxrefxrefxrefxref
        complexed with so4, zn
        1. chain c [38332] picpiclink
    11. Human (Homo sapiens), ubc9 [TaxId: 9606] [54503] (12)
      identical sequence in many other species
      1. 2uyz picpicxref
        annotated as mouse protein in PDB
        complexed with na; mutant
        1. region a:3-158 [145768] picpiclink
      2. 2grn picpicxref
        automatically matched to d1u9aa_
        1. region a:1-157 [135568] picpiclink
      3. 1u9a picpic
        CASP2
        1. chain a [38333] picpiclink
      4. 1u9b picpic
        mutant
        1. chain a [38334] picpiclink
      5. 2vrr picpicxref
        automatically matched to d1u9aa_
        complexed with fmt, na
        1. region a:2-158 [153522] picpiclink
      6. 2pe6 picpicxref
        automatically matched to d1u9aa_
        1. region a:1-157 [139667] picpiclink
      7. 1kps picpicxref
        complexed with so4
        1. chain a [68786] picpiclink
        2. chain c [68788] picpiclink
      8. 1a3s picpic
        1. chain a [38335] picpiclink
      9. 2o25 picpicxrefxrefxrefxref
        automatically matched to d1u9aa_
        1. region c:2-158 [138890] picpiclink
      10. 2o25 picpicxrefxrefxrefxref
        automatically matched to d1u9aa_
        1. region d:2-157 [138891] picpiclink
      11. 1z5s picpicxrefxref
        automatically matched to d1u9aa_
        1. region a:2-157 [124491] picpiclink
      12. 2px9 picpic
        automatically matched to d1u9aa_
        1. region b:1-158 [149906] picpiclink
    12. Human (Homo sapiens), ubch10 [TaxId: 9606] [64243] (1)
      1. 1i7k picpic
        mutant
        1. chain a [61889] picpiclink
        2. chain b [61890] picpiclink
    13. Human (Homo sapiens), ubc2b [TaxId: 9606] [102840] (1)
      E2-17 kDa
      1. 1jas picpic
        1. chain a [90882] picpiclink
    14. Human (Homo sapiens), ubch5b [TaxId: 9606] [102841] (14)
      SQ P62837
      E2-17 kDa 2
      1. 2esk picpic
        automatically matched to d1ur6a_
        1. region a:1-147 [132326] picpiclink
      2. 2esq picpic
        mutant
        1. region a:1-147 [132343] picpiclink
      3. 2esp picpic
        complexed with cl, mpd; mutant
        1. region a:1-147 [132342] picpiclink
      4. 2eso picpic
        mutant
        1. region a:1-147 [132341] picpiclink
      5. 2c4o picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region a:1-147 [129838] picpiclink
      6. 2c4o picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region b:1-147 [129839] picpiclink
      7. 2c4o picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region c:1-147 [129840] picpiclink
      8. 2c4o picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region d:1-147 [129841] picpiclink
      9. 2clw picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region a:1-147 [130596] picpiclink
      10. 2clw picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region b:1-147 [130597] picpiclink
      11. 2clw picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region c:1-147 [130598] picpiclink
      12. 2clw picpic
        automatically matched to d1ur6a_
        complexed with gol, so4
        1. region d:1-147 [130599] picpiclink
      13. 1ur6 picpicxref
        complexed with zn
        1. chain a [99811] picpiclink
      14. 1w4u picpic
        1. chain a [114194] picpiclink
    15. Clam (Spisula solidissima), E-2C [TaxId: 6584] [54504] (1)
      1. 2e2c picpic
        1. chain a [38336] picpiclink
    16. Nematode (Caenorhabditis elegans), E2-19 kDa [TaxId: 6239] [89862] (1)
      1. 1pzv picpic
        1. chain a [88342] picpiclink
    17. Nematode (Caenorhabditis elegans), E2-21.5 kDa [TaxId: 6239] [102842] (2)
      1. 1z3d picpic
        automatically matched to d1q34a_
        1. region a:2-150 [124399] picpiclink
      2. 1q34 picpic
        1. chain a [95658] picpiclink
        2. chain b [95659] picpiclink
        3. chain c [95660] picpiclink
    18. Human (Homo sapiens), ubch8 [TaxId: 9606] [117850] (1)
      SQ Q96LR5 54-201
      1. 1y6l picpic
        1. chain a [116509] picpiclink
        2. chain b [116510] picpiclink
        3. chain c [116511] picpiclink
    19. Human(Homo sapiens), E2 S [TaxId: 9606] [143048] (2)
      SQ Q16763 6-156
      1. 1zdn picpic
        complexed with na
        1. region a:6-156 [124943] picpiclink
      2. 1zdn picpic
        automatically matched to 1ZDN A:6-156
        complexed with na
        1. region b:10-156 [124944] picpiclink
    20. Leishmania major [TaxId: 5664] [143049] (3)
      SQ Q4Q5L3 9-166
      Ubiquitin carrier protein 4, putative
      1. 1yf9 picpic
        complexed with cl
        1. region a:13-170 [123054] picpiclink
      2. 1yf9 picpic
        automatically matched to 1YF9 A:13-170
        complexed with cl
        1. region b:13-170 [123055] picpiclink
      3. 1yf9 picpic
        automatically matched to 1YF9 A:13-170
        complexed with cl
        1. region c:13-170 [123056] picpiclink
    21. Human (Homo sapiens), E2 J2 [TaxId: 9606] [143050] (2)
      SQ Q5T7L1 12-168
      ubc6 homologue
      1. 2f4w picpic
        1. region a:12-168 [132958] picpiclink
      2. 2f4w picpic
        automatically matched to 2F4W A:12-168
        1. region b:12-168 [132959] picpiclink
    22. Human (Homo sapiens), E2 variant 1 [TaxId: 9606] [143051] (5)
      SQ Q13404 80-221! SQ Q13404 82-220
      1. 2a4d picpic
        1. region a:82-220 [126152] picpiclink
      2. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        1. region c:33-174 [129687] picpiclink
      3. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C2V C:33-174
        1. region f:36-174 [129689] picpiclink
      4. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C2V C:33-174
        1. region i:36-174 [129691] picpiclink
      5. 2c2v picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C2V C:33-174
        1. region l:36-174 [129693] picpiclink
    23. Human (Homo sapiens), E2 L6 [TaxId: 9606] [143052] (3)
      SQ O14933 2-151
      1. 1wzv picpic
        1. region a:2-151 [121529] picpiclink
      2. 1wzv picpic
        automatically matched to 1WZV A:2-151
        1. region b:2-151 [121530] picpiclink
      3. 1wzw picpic
        automatically matched to 1WZV A:2-151
        1. region a:2-151 [121531] picpiclink
    24. Human (Homo sapiens), E2 U [TaxId: 9606] [143053] (1)
      SQ Q5VVX9 1-148
      1. 1yrv picpic
        1. region a:1-148 [123941] picpiclink
    25. Human (Homo sapiens), E2 D3 [TaxId: 9606] [143054] (5)
      SQ P61077 1-147
      1. 1x23 picpic
        1. region a:1-147 [121615] picpiclink
      2. 1x23 picpic
        automatically matched to 1X23 A:1-147
        1. region b:1-147 [121616] picpiclink
      3. 1x23 picpic
        automatically matched to 1X23 A:1-147
        1. region c:1-147 [121617] picpiclink
      4. 1x23 picpic
        automatically matched to 1X23 A:1-147
        1. region d:1-147 [121618] picpiclink
      5. 2fuh picpicxref
        automatically matched to 1X23 A:1-147
        1. region a:2-147 [134173] picpiclink
    26. Human (Homo sapiens), E2 H [TaxId: 9606] [143055] (2)
      SQ P62256 4-155
      1. 1yh6 picpic
        1. region a:23-174 [123160] picpiclink
      2. 1yh6 picpic
        automatically matched to 1YH6 A:23-174
        1. region b:25-174 [123161] picpiclink
    27. Human (Homo sapiens), E2 G1 [TaxId: 9606] [143056] (1)
      SQ P62253 7-131
      1. 2awf picpic
        1. region a:7-131 [127432] picpiclink
    28. Human (Homo sapiens), E2 T [TaxId: 9606] [143057] (1)
      SQ Q9NPD8 1-154
      Hspc150
      1. 1yh2 picpic
        1. region a:1-154 [123158] picpiclink
    29. Human (Homo sapiens), E2 M [TaxId: 9606] [143058] (2)
      SQ P61081 27-183
      the extra N-terminal peptide, bound to the heterodimeric E1 enzyme for NEDD8, can be seen in the PDB entry 1tt5, chains E and F
      1. 1y8x picpicxref
        1. region a:27-183 [122769] picpiclink
      2. 2nvu picpicxrefxrefxrefxrefxref
        complexed with atp, mg, zn; mutant
        1. region c:3-183 [145698] picpiclink
    30. Toxoplasma gondii [TaxId: 5811] [143059] (1)
      1. 2ayv picpic
        complexed with unx
        1. region a:1-146 [127572] picpiclink
    31. Caenorhabditis elegans, E2 2 [TaxId: 6239] [143060] (1)
      SQ P35129 1-147
      1. 1z2u picpic
        complexed with bu3, cl, na, unx
        1. region a:1-147 [124389] picpiclink
    32. Xenopus laevis [TaxId: 8355] [160080] (1)
      1. 3eb6 picpic
        automatically matched to d1ur6a_
        complexed with zn
        1. region b:1-147 [158081] picpiclink
  2. Ubiquitin-protein ligase W (E2 W) [143061]
    forms segment-swapped dimer
    1. Human (Homo sapiens) [TaxId: 9606] [143062] (2)
      SQ Q96B02 1-117
      1. 2a7l picpic
        complexed with na
        1. region a:1-117 [126350] picpiclink
      2. 2a7l picpic
        automatically matched to 2A7L A:1-117
        complexed with na
        1. region b:1-117 [126351] picpiclink
  3. Ubiquitin-conjugating enzyme E2-25 kDa, E2 domain [143063]
    ubc1 homologue; also contains the C-terminal UBA domain
    1. Human (Homo sapiens) [TaxId: 9606] [143064] (5)
      SQ P61086 1-156
      1. 3e46 picpicxref
        automatically matched to d1ylaa2
        complexed with ca; mutant
        1. region a:1-156 [157995] picpiclink
      2. 1yla picpicxrefxref
        1. region a:1-156 [123642] picpiclink
      3. 1yla picpicxrefxref
        automatically matched to 1YLA A:1-156
        1. region b:1-156 [123644] picpiclink
      4. 2o25 picpicxrefxrefxrefxref
        automatically matched to 1YLA A:1-156
        1. region a:1-156 [138887] picpiclink
      5. 2o25 picpicxrefxrefxrefxref
        automatically matched to 1YLA A:1-156
        1. region b:3-156 [138889] picpiclink
    2. Cow (Bos taurus) [TaxId: 9913] [143065] (2)
      SQ P61085 1-154
      1. 2bep picpic
        complexed with bme
        1. region a:1-154 [128385] picpiclink
      2. 2bf8 picpicxref
        automatically matched to 2BEP A:1-154
        1. region a:2-154 [128411] picpiclink
  4. Hypothetical protein Tgtwinscan_2721, E2 domain [143066]
    1. Toxoplasma gondii [TaxId: 5811] [143067] (2)
      1. 2f4z picpic
        complexed with gol, unx
        1. region a:32-192 [132963] picpiclink
      2. 2f4z picpic
        automatically matched to 2F4Z A:32-192
        complexed with gol, unx
        1. region b:33-192 [132964] picpiclink
  5. Ubiquitin-conjugating enzyme E2 Q2, C-terminal domain [143068]
    this proteins contains the N-terminal RWD domain
    1. Human (Homo sapiens) [TaxId: 9606] [143069] (1)
      SQ Q8WVN8 201-362
      1. 1zuo picpic
        complexed with bme
        1. region a:201-362 [125680] picpiclink
  6. Putative ubiquitin-conjugating enzyme, E2 domain [143070]
    1. Plasmodium chabaudi [TaxId: 5825] [143071] (1)
      SQ Q4Y037 88-196
      1. 2fo3 picpic
        1. region a:9-117 [133868] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk