Structural Classification of Proteins
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Protein: Amyloid beta precursor protein-binding protein 1, APPBP1 from Human (Homo sapiens) [TaxId: 9606]

SQ Q13564

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Activating enzymes of the ubiquitin-like proteins [69571]
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 32145678; strands 6 and 8 are antiparallel to the rest
  4. Superfamily: Activating enzymes of the ubiquitin-like proteins [69572]
    transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins
    the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds
    link to SUPERFAMILY database - Superfamily
  5. Family: Ubiquitin activating enzymes (UBA) [89763]
    the common fold is elaborated with additional (sub)domains
  6. Protein: Amyloid beta precursor protein-binding protein 1, APPBP1 [89766]
    a subunit of the heterodimeric E1 enzyme for NEDD8; contains a large insertion (residues 170-487) that can be divided into 3 units similar to the UBA3 insertion
  7. Species: Human (Homo sapiens) [TaxId: 9606] [89767]
    SQ Q13564

PDB Entry Domains:

  1. 1yov picpicxrefxref
    automatically matched to d1ngva_
    complexed with zn
    1. region a:6-534 [123785] picpiclink
  2. 1yov picpicxrefxref
    automatically matched to d1ngva_
    complexed with zn
    1. region c:9-534 [123787] picpiclink
  3. 1tt5 picpicxref
    complexed with zn
    1. chain a [107291] picpiclink
    2. chain c [107293] picpiclink
  4. 2nvu picpicxrefxrefxrefxrefxref
    automatically matched to d1ngva_
    complexed with atp, mg, zn; mutant
    1. region a:6-534 [138660] picpiclink
  5. 1r4m picpicxrefxref
    complexed with zn; mutant
    1. chain a [96999] picpiclink
    2. chain c [97001] picpiclink
    3. chain e [97003] picpiclink
    4. chain g [97005] picpiclink
  6. 3dbh picpicxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region a:6-534 [157468] picpiclink
  7. 3dbh picpicxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region c:6-534 [157469] picpiclink
  8. 3dbh picpicxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region e:6-534 [157470] picpiclink
  9. 3dbh picpicxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region g:6-534 [157471] picpiclink
  10. 3dbl picpicxrefxrefxrefxrefxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region a:6-534 [157473] picpiclink
  11. 3dbl picpicxrefxrefxrefxrefxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region c:6-534 [157475] picpiclink
  12. 3dbl picpicxrefxrefxrefxrefxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region e:6-534 [157477] picpiclink
  13. 3dbl picpicxrefxrefxrefxrefxref
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region g:6-534 [157479] picpiclink
  14. 3dbr picpic
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region a:6-534 [157482] picpiclink
  15. 3dbr picpic
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region c:6-534 [157483] picpiclink
  16. 3dbr picpic
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region e:6-534 [157484] picpiclink
  17. 3dbr picpic
    automatically matched to d1tt5a_
    complexed with zn; mutant
    1. region g:6-534 [157485] picpiclink
  18. 1r4n picpicxrefxref
    complexed with atp, zn; mutant
    1. chain a [97011] picpiclink
    2. chain c [97013] picpiclink
    3. chain e [97015] picpiclink
    4. chain g [97017] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk