Structural Classification of Proteins

Family: UBC-related

Lineage:

Root: scop
Class: Alpha and beta proteins (a+b) [53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold: UBC-like [54494]
alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
Superfamily: UBC-like [54495]
uperfamily
Family: UBC-related [54496]

Protein Domains:

Ubiquitin conjugating enzyme, UBC [54497]
1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [54498] (1)
2. Baker's yeast (Saccharomyces cerevisiae), ubc1 [TaxId: 4932] [69685] (3)
  SQ P21734
3. Baker's yeast (Saccharomyces cerevisiae), ubc2 (RAD6) [TaxId: 4932] [54499] (1)
4. Baker's yeast (Saccharomyces cerevisiae), ubc4 [TaxId: 4932] [54500] (1)
5. Baker's yeast (Saccharomyces cerevisiae), ubc7 [TaxId: 4932] [54501] (1)
6. Baker's yeast (Saccharomyces cerevisiae), ubc13 [TaxId: 4932] [64239] (3)
7. Baker's yeast (Saccharomyces cerevisiae), mms2 [TaxId: 4932] [64241] (2)
8. Human (Homo sapiens), ubc13 [TaxId: 9606] [64240] (5)
9. Human (Homo sapiens), mms2 [TaxId: 9606] [64242] (3)
10. Human (Homo sapiens), ubch7 [TaxId: 9606] [54502] (2)
11. Human (Homo sapiens), ubc9 [TaxId: 9606] [54503] (12)
  identical sequence in many other species
12. Human (Homo sapiens), ubch10 [TaxId: 9606] [64243] (1)
13. Human (Homo sapiens), ubc2b [TaxId: 9606] [102840] (1)
  E2-17 kDa
14. Human (Homo sapiens), ubch5b [TaxId: 9606] [102841] (14)
  SQ P62837
  E2-17 kDa 2
15. Clam (Spisula solidissima), E-2C [TaxId: 6584] [54504] (1)
16. Nematode (Caenorhabditis elegans), E2-19 kDa [TaxId: 6239] [89862] (1)
17. Nematode (Caenorhabditis elegans), E2-21.5 kDa [TaxId: 6239] [102842] (2)
18. Human (Homo sapiens), ubch8 [TaxId: 9606] [117850] (1)
  SQ Q96LR5 54-201
19. Human(Homo sapiens), E2 S [TaxId: 9606] [143048] (2)
  SQ Q16763 6-156
20. Leishmania major [TaxId: 5664] [143049] (3)
  SQ Q4Q5L3 9-166
  Ubiquitin carrier protein 4, putative
21. Human (Homo sapiens), E2 J2 [TaxId: 9606] [143050] (2)
  SQ Q5T7L1 12-168
  ubc6 homologue
22. Human (Homo sapiens), E2 variant 1 [TaxId: 9606] [143051] (5)
  SQ Q13404 80-221! SQ Q13404 82-220
23. Human (Homo sapiens), E2 L6 [TaxId: 9606] [143052] (3)
  SQ O14933 2-151
24. Human (Homo sapiens), E2 U [TaxId: 9606] [143053] (1)
  SQ Q5VVX9 1-148
25. Human (Homo sapiens), E2 D3 [TaxId: 9606] [143054] (5)
  SQ P61077 1-147
26. Human (Homo sapiens), E2 H [TaxId: 9606] [143055] (2)
  SQ P62256 4-155
27. Human (Homo sapiens), E2 G1 [TaxId: 9606] [143056] (1)
  SQ P62253 7-131
28. Human (Homo sapiens), E2 T [TaxId: 9606] [143057] (1)
  SQ Q9NPD8 1-154
  Hspc150
29. Human (Homo sapiens), E2 M [TaxId: 9606] [143058] (2)
  SQ P61081 27-183
  the extra N-terminal peptide, bound to the heterodimeric E1 enzyme for NEDD8, can be seen in the PDB entry 1tt5, chains E and F
30. Toxoplasma gondii [TaxId: 5811] [143059] (1)
31. Caenorhabditis elegans, E2 2 [TaxId: 6239] [143060] (1)
  SQ P35129 1-147
32. Xenopus laevis [TaxId: 8355] [160080] (1)
Ubiquitin-protein ligase W (E2 W) [143061]
forms segment-swapped dimer
1. Human (Homo sapiens) [TaxId: 9606] [143062] (2)
  SQ Q96B02 1-117
Ubiquitin-conjugating enzyme E2-25 kDa, E2 domain [143063]
ubc1 homologue; also contains the C-terminal UBA domain
1. Human (Homo sapiens) [TaxId: 9606] [143064] (5)
  SQ P61086 1-156
2. Cow (Bos taurus) [TaxId: 9913] [143065] (2)
  SQ P61085 1-154
Hypothetical protein Tgtwinscan_2721, E2 domain [143066]
1. Toxoplasma gondii [TaxId: 5811] [143067] (2)
Ubiquitin-conjugating enzyme E2 Q2, C-terminal domain [143068]
this proteins contains the N-terminal RWD domain
1. Human (Homo sapiens) [TaxId: 9606] [143069] (1)
  SQ Q8WVN8 201-362
Putative ubiquitin-conjugating enzyme, E2 domain [143070]
1. Plasmodium chabaudi [TaxId: 5825] [143071] (1)
  SQ Q4Y037 88-196