Structural Classification of Proteins
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Protein: Insulin receptor from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Protein kinase-like (PK-like) [56111]
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily: Protein kinase-like (PK-like) [56112]
    shares functional and structural similarities with the ATP-grasp fold and PIPK
    link to SUPERFAMILY database - Superfamily
  5. Family: Protein kinases, catalytic subunit [88854]
    members organized in the groups and subfamiles specified by the comments
  6. Protein: Insulin receptor [56162]
    PTK group; InsR subfamily; membrane spanning protein tyrosine kinase
  7. Species: Human (Homo sapiens) [TaxId: 9606] [56163]

PDB Entry Domains:

  1. 3bu3 picpic
    automatically matched to d1rqqa_
    1. region a:987-1283 [155590] picpiclink
  2. 1ir3 picpic
    complexed with anp, mg; mutant
    1. chain a [41702] picpiclink
  3. 3bu6 picpic
    automatically matched to d1rqqa_
    1. region a:987-1283 [155592] picpiclink
  4. 1p14 picpic
    mutant
    1. chain a [87660] picpiclink
  5. 1irk picpic
    complexed with emc; mutant
    1. chain a [41703] picpiclink
  6. 3bu5 picpic
    automatically matched to d1rqqa_
    complexed with atp, mg
    1. region a:987-1283 [155591] picpiclink
  7. 2b4s picpicxref
    automatically matched to d1rqqa_
    complexed with so4
    1. region b:987-1283 [127854] picpiclink
  8. 2b4s picpicxref
    automatically matched to d1rqqa_
    complexed with so4
    1. region d:987-1283 [127855] picpiclink
  9. 1i44 picpic
    complexed with acp, mg; mutant
    1. chain a [61664] picpiclink
  10. 1gag picpic
    complexed with 112, mg; mutant
    1. chain a [41704] picpiclink
  11. 1rqq picpicxref
    complexed with adaptor protein Aps
    complexed with 112, mn; mutant
    1. chain a [97760] picpiclink
    2. chain b [97761] picpiclink
  12. 2auh picpic
    automatically matched to d1rqqa_
    complexed with ca
    1. region a:987-1283 [127329] picpiclink
  13. 2z8c picpic
    automatically matched to d1gaga_
    complexed with s91; mutant
    1. region a:984-1283 [154208] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk