Structural Classification of Proteins
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Protein: Tyrosine phosphatase from Human (Homo sapiens), 1B [TaxId: 9606]

SQ P18031 2-300 ! SQ P18031 1-298 ! SQ P18031 2-299

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: (Phosphotyrosine protein) phosphatases II [52798]
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. Superfamily: (Phosphotyrosine protein) phosphatases II [52799]
    share with the family I the common active site structure with a circularly permuted topology
    link to SUPERFAMILY database - Superfamily
  5. Family: Higher-molecular-weight phosphotyrosine protein phosphatases [52805]
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. Protein: Tyrosine phosphatase [52806]
  7. Species: Human (Homo sapiens), 1B [TaxId: 9606] [52807]
    SQ P18031 2-300 ! SQ P18031 1-298 ! SQ P18031 2-299

PDB Entry Domains:

  1. 2f71 picpic
    automatically matched to d1q1ma_
    complexed with cl, mg, un7
    1. region a:2-298 [133070] picpiclink
  2. 2cm2 picpic
    automatically matched to d1ptta_
    complexed with mpd
    1. region a:2-283 [130610] picpiclink
  3. 2f6z picpic
    automatically matched to d1q1ma_
    complexed with cl, mg, un5
    1. region a:2-298 [133068] picpiclink
  4. 2f6t picpic
    automatically matched to d1q1ma_
    complexed with 1c2, cl, mg
    1. region a:2-298 [133060] picpiclink
  5. 1pa1 picpic
    complexed with cl, mg; mutant
    1. chain a [94404] picpiclink
  6. 2f6v picpic
    automatically matched to d1q1ma_
    complexed with cl, mg, sk2
    1. region a:2-298 [133063] picpiclink
  7. 2cmb picpic
    automatically matched to d1ptta_
    complexed with bog, f17
    1. region a:2-281 [130619] picpiclink
  8. 1eeo picpic
    complexed with mg; mutant
    1. chain a [32655] picpiclink
  9. 1pty picpic
    complexed with mo6; mutant
    1. chain a [32656] picpiclink
  10. 2cne picpic
    automatically matched to d1ptta_
    complexed with bog, dfj, so4
    1. region a:2-281 [130640] picpiclink
  11. 2cnh picpic
    automatically matched to d1q1ma_
    complexed with ca, izb
    1. region a:3-299 [130643] picpiclink
  12. 1sug picpic
    complexed with gol, trs
    1. chain a [106022] picpiclink
  13. 1g7f picpic
    complexed with inz
    1. chain a [60330] picpiclink
  14. 1aax picpic
    complexed with bpm, mo6; mutant
    1. chain a [32657] picpiclink
  15. 1een picpic
    complexed with acy, mg, pbf; mutant
    1. chain a [32658] picpiclink
  16. 2cng picpic
    automatically matched to d1q1ma_
    complexed with gol, ize, mg
    1. region a:3-299 [130642] picpiclink
  17. 1oem picpic
    1. chain x [86916] picpiclink
  18. 1t49 picpic
    complexed with 892, mo6
    1. chain a [106403] picpiclink
  19. 2f70 picpic
    automatically matched to d1q1ma_
    complexed with cl, mg, un6
    1. region a:2-298 [133069] picpiclink
  20. 2bge picpic
    automatically matched to d1q1ma_
    complexed with t2d
    1. region a:2-298 [128475] picpiclink
  21. 1c88 picpic
    complexed with ota
    1. chain a [32659] picpiclink
  22. 2f6y picpic
    automatically matched to d1q1ma_
    complexed with cl, ent, mg
    1. region a:2-298 [133067] picpiclink
  23. 2azr picpic
    automatically matched to d1q1ma_
    complexed with 982
    1. region a:2-298 [127614] picpiclink
  24. 1pxh picpic
    complexed with acy, mg, sna
    1. chain a [95288] picpiclink
  25. 1c83 picpic
    complexed with oai
    1. chain a [32660] picpiclink
  26. 1g1f picpic
    mutant
    1. chain a [32662] picpiclink
  27. 2cni picpic
    automatically matched to d1q1ma_
    complexed with izf, mg
    1. region a:3-299 [130644] picpiclink
  28. 2b07 picpic
    automatically matched to d1q1ma_
    complexed with 598
    1. region a:2-298 [127625] picpiclink
  29. 1oev picpic
    complexed with mg, ocs
    1. chain a [86923] picpiclink
  30. 1ony picpic
    complexed with 588
    1. chain a [87180] picpiclink
  31. 2f6w picpic
    automatically matched to d1q1ma_
    complexed with cl, mg, un3
    1. region a:2-298 [133064] picpiclink
  32. 2hb1 picpic
    automatically matched to d1ptta_
    complexed with 512
    1. region a:2-283 [136304] picpiclink
  33. 2cm8 picpic
    automatically matched to d1q1ma_
    complexed with f16, mg
    1. region a:3-299 [130617] picpiclink
  34. 1oes picpic
    complexed with mg
    1. chain a [86920] picpiclink
  35. 1i57 picpic
    complexed with cl, mg; mutant
    1. chain a [61772] picpiclink
  36. 1oeo picpic
    complexed with ocs
    1. chain x [86917] picpiclink
  37. 2cm7 picpic
    automatically matched to d1q1ma_
    complexed with izd
    1. region a:3-299 [130616] picpiclink
  38. 1bzj picpic
    complexed with inh
    1. chain a [32667] picpiclink
  39. 1ecv picpic
    complexed with 878, act
    1. chain a [32661] picpiclink
  40. 1ph0 picpic
    complexed with 418
    1. chain a [88074] picpiclink
  41. 1q6s picpic
    complexed with 214, cl, mg, mpd
    1. chain a [95994] picpiclink
    2. chain b [95995] picpiclink
  42. 2cmc picpic
    automatically matched to d1ptta_
    complexed with bog, dfm, so4
    1. region a:2-281 [130620] picpiclink
  43. 2cnf picpic
    automatically matched to d1q1ma_
    complexed with f32, mg
    1. region a:3-299 [130641] picpiclink
  44. 1g1g picpic
    mutant
    1. chain a [32669] picpiclink
  45. 2b4s picpicxrefxref
    automatically matched to d1g1ga_
    complexed with so4
    1. region a:2-292 [127853] picpiclink
  46. 1oet picpic
    complexed with cea, mg
    1. chain a [86921] picpiclink
  47. 1ptv picpic
    complexed with phs; mutant
    1. chain a [32665] picpiclink
  48. 1kav picpic
    complexed with fep
    1. chain a [72266] picpiclink
  49. 1nl9 picpic
    complexed with 989
    1. chain a [85847] picpiclink
  50. 1q6n picpic
    complexed with cl, mg, p90
    1. chain a [95984] picpiclink
    2. chain b [95985] picpiclink
  51. 1pyn picpic
    complexed with 941
    1. chain a [95369] picpiclink
  52. 1c87 picpic
    complexed with opa
    1. chain a [32663] picpiclink
  53. 2bgd picpic
    automatically matched to d1q1ma_
    complexed with cl, na, po4, t1d
    1. region a:2-298 [128474] picpiclink
  54. 1wax picpic
    automatically matched to d1q1ma_
    complexed with lo1, mg
    1. region a:2-299 [120824] picpiclink
  55. 1t48 picpic
    complexed with bb3
    1. chain a [106402] picpiclink
  56. 1qxk picpic
    complexed with 429
    1. chain a [96532] picpiclink
  57. 1q6m picpic
    complexed with p27
    1. chain a [95983] picpiclink
  58. 2cm3 picpic
    automatically matched to d1ptta_
    complexed with ca
    1. region a:7-281 [130611] picpiclink
  59. 2cm3 picpic
    automatically matched to d1ptta_
    complexed with ca
    1. region b:7-281 [130612] picpiclink
  60. 2cma picpic
    automatically matched to d1q1ma_
    complexed with f20
    1. region a:3-299 [130618] picpiclink
  61. 2h4g picpic
    automatically matched to d1ptta_
    complexed with 694
    1. region a:2-283 [136074] picpiclink
  62. 1gfy picpic
    complexed with col; mutant
    1. chain a [32666] picpiclink
  63. 1q6j picpic
    complexed with 335
    1. chain a [95979] picpiclink
  64. 1nny picpic
    complexed with 515
    1. chain a [85912] picpiclink
  65. 2h4k picpic
    automatically matched to d1ptta_
    complexed with 509
    1. region a:2-283 [136077] picpiclink
  66. 1bzc picpic
    complexed with tpi
    1. chain a [32670] picpiclink
  67. 1g1h picpic
    mutant
    1. chain a [32672] picpiclink
  68. 1jf7 picpic
    complexed with tbh
    1. chain a [66619] picpiclink
    2. chain b [66620] picpiclink
  69. 1xbo picpic
    complexed with ix1
    1. chain a [115079] picpiclink
  70. 1q6t picpic
    complexed with 600, mg
    1. chain a [95996] picpiclink
    2. chain b [95997] picpiclink
  71. 1q6p picpic
    complexed with 213, cl
    1. chain a [95988] picpiclink
    2. chain b [95989] picpiclink
  72. 1bzh picpic
    complexed with inh
    1. chain a [32664] picpiclink
  73. 1onz picpic
    complexed with 968
    1. chain a [87181] picpiclink
  74. 1c86 picpic
    complexed with opa; mutant
    1. chain a [32668] picpiclink
  75. 1nz7 picpic
    complexed with 901
    1. chain a [86443] picpiclink
  76. 1no6 picpic
    complexed with 794
    1. chain a [85922] picpiclink
  77. 1q1m picpic
    complexed with 234
    1. chain a [95595] picpiclink
  78. 1kak picpic
    complexed with fnp
    1. chain a [72253] picpiclink
  79. 1c84 picpic
    complexed with 761
    1. chain a [32671] picpiclink
  80. 1a5y picpic
    cysteinyl-phosphate intermediate
    1. chain a [32673] picpiclink
  81. 1g7g picpic
    complexed with inx
    1. chain a [60331] picpiclink
  82. 1l8g picpic
    complexed with dbd
    1. chain a [73689] picpiclink
  83. 1nwl picpic
    complexed with 964, mo6; mutant
    1. chain a [86300] picpiclink
  84. 1ptu picpic
    complexed with nh2, phs; mutant
    1. chain a [32675] picpiclink
  85. 1lqf picpic
    complexed with bgd
    1. chain a [74187] picpiclink
    2. chain b [74188] picpiclink
    3. chain c [74189] picpiclink
    4. chain d [74190] picpiclink
  86. 1t4j picpic
    complexed with frj
    1. chain a [106422] picpiclink
  87. 2hnq picpic
    complexed with wo4
    1. chain a [32676] picpiclink
  88. 1oeu picpic
    complexed with csw, mg
    1. chain a [86922] picpiclink
  89. 1c85 picpic
    complexed with oba
    1. chain a [32674] picpiclink
  90. 2hnp picpic
    1. chain a [32678] picpiclink
  91. 1ptt picpic
    complexed with ace, phs; mutant
    1. chain a [32677] picpiclink
  92. 1nwe picpic
    complexed with fg1; mutant
    1. chain a [86298] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk