Structural Classification of Proteins
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Fold: beta-Grasp (ubiquitin-like)

core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: beta-Grasp (ubiquitin-like) [54235]
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

Superfamilies:

  1. Ubiquitin-like [54236] (8)
    link to SUPERFAMILY database - Superfamily
    1. Ubiquitin-related [54237] (47)
      Pfam 00240
      1. Ubiquitin [54238]
        1. Human (Homo sapiens) [TaxId: 9606] [54239] (102) picpic
          SQ P62988
          identical sequence in many other species
        2. Baker's yeast (Saccharomyces cerevisiae), smt3 [TaxId: 4932] [89830] (7) picpic
        3. Synthetic, based on Saccharomyces cerevisiae sequence [54240] (1) picpic
      2. SUMO-1 (smt3 homologue) [54241]
        1. Human (Homo sapiens) [TaxId: 9606] [54242] (17) picpic
          SQ Q93068
        2. Baker's yeast (Saccharomyces cerevisiae), smt3 [TaxId: 4932] [54243] (4) picpic
      3. Nedd8 [54244]
        1. Human (Homo sapiens) [TaxId: 9606] [54245] (7) picpic
          SQ Q15843
      4. Elongin B [54246]
        1. Human (Homo sapiens) [TaxId: 9606] [54247] (7) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [142930] (1) picpic
          SQ P62869 1-98
      5. Rub1 [54248]
        1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [54249] (1) picpic
      6. Ubiquitin-like modifier protein hub1 [82579]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82580] (1) picpic
      7. Ubiquitin-like N-terminal domain of PLIC-2 [75358]
        1. Human (Homo sapiens) [TaxId: 9606] [75359] (1) picpic
      8. Ubiquitin-like domain of parkin [89831]
        1. Human (Homo sapiens) [TaxId: 9606] [89832] (1) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [89833] (2) picpic
      9. Ubiquitin-like domain of Rad23 homolog A (Hhr23a) [102775]
        1. Human (Homo sapiens) [TaxId: 9606] [102776] (4) picpic
      10. Ubiquitin-like domain of Rad23 homolog B (Hhr23B) [102777]
        1. Human (Homo sapiens) [TaxId: 9606] [102778] (2) picpic
          SQ P54727 1-82
      11. Ubiquitin-like protein 5, ubl5 [102779]
        1. Human (Homo sapiens) [TaxId: 9606] [102780] (1) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [102781] (1) picpic
      12. Hypothetical protein At3g01050 [102782]
        1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [102783] (1) picpic
      13. Ubiquitin-like protein 3300001g02rik [102784]
        1. Mouse (Mus musculus) [TaxId: 10090] [102785] (1) picpic
      14. Ubiquitin-like domain of tubulin folding cofactor B [102786]
        1. Nematode (Caenorhabditis elegans) [TaxId: 6239] [102787] (1) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [117798] (1) picpic
          SQ Q9D1E6 11-92
      15. 1700011n24rik protein [110796]
        1. Mouse (Mus musculus) [TaxId: 10090] [110797] (1) picpic
          SQ Q9DAF3 1-89
      16. 8430435i17rik protein [110798]
        1. Mouse (Mus musculus) [TaxId: 10090] [110799] (1) picpic
          SQ Q8BGR9 3-79
      17. hypothetical D7wsu128e protein [110800]
        1. Mouse (Mus musculus) [TaxId: 10090] [110801] (1) picpic
          SQ Q78JW9 76-157
      18. Splicing factor 3 subunit 1, C-terminal domain [117799]
        1. Mouse (Mus musculus) [TaxId: 10090] [117800] (1) picpic
          SQ Q8K4Z5 685-786
        2. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117801] (1) picpic
          SQ Q8RXF1 683-780; T5E21.13/At1g14650
        3. Human (Homo sapiens) [TaxId: 9606] [142931] (1) picpic
          SQ Q15459 704-789
      19. Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, HERPUD1 [117802]
        1. Human (Homo sapiens) [TaxId: 9606] [117803] (1) picpic
          SQ Q15011 10-90
      20. Ubiquitin carboxyl-terminal hydrolase 14 [117804]
        1. Mouse (Mus musculus) [TaxId: 10090] [117805] (1) picpic
          SQ Q9JMA1 3-85
      21. Ubiquitin-like protein 3, Ubl3 [117806]
        1. Mouse (Mus musculus) [TaxId: 10090] [117807] (1) picpic
          SQ Q9Z2M6 1-103
      22. 2'-5'-oligoadenylate synthetase-like protein, OASL [117808]
        1. Human (Homo sapiens) [TaxId: 9606] [117809] (1) picpic
          SQ Q15646 434-507
      23. Ubiquitin-like protein bab25500 (2010008E23Rik) [117810]
        1. Mouse (Mus musculus) [TaxId: 10090] [117811] (1) picpic
          SQ Q9D8C5 163-244
      24. Tubulin-folding protein TbcE [117812]
        1. Mouse (Mus musculus) [TaxId: 10090] [117813] (1) picpic
          SQ Q8CIV8 441-524
      25. NEDD8 ultimate buster-1, NUB1 [117814]
        1. Human (Homo sapiens) [TaxId: 9606] [117815] (1) picpic
          SQ Q9Y5A7 75-161
      26. SUMO-2 [117816]
        1. Human (Homo sapiens) [TaxId: 9606] [117817] (13) picpic
          SQ P61956
      27. Bag-family molecular chaperone regulator-1 [142932]
        1. Human (Homo sapiens) [TaxId: 9606] [142933] (1) picpic
          SQ Q99933 72-152
          the BAG domain structure is also known (scop_sp 63494)
      28. NPL4-like protein 1 [142934]
        1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [142935] (1) picpic
          SQ Q9LYC2 2-95
      29. Interferon-induced 15 kDa protein [142936]
        1. Human (Homo sapiens) [TaxId: 9606] [142937] (2) picpic
          SQ P05161 2-77! SQ P05161 78-153
      30. Ubiquitin-like protein smt3a, SUMO-3 [142938]
        1. Human (Homo sapiens) [TaxId: 9606] [142939] (1) picpic
          SQ P55854 14-92
      31. DSK2 [142940]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [142941] (5) picpic
          SQ P48510 2-74
      32. Ubiquitin-like protein 7 [142942]
        1. Mouse (Mus musculus) [TaxId: 10090] [142943] (1) picpic
          SQ Q91W67 1-94
      33. Ubiquitin-like PHD and RING finger domain-containing protein 2 [142944]
        1. Human (Homo sapiens) [TaxId: 9606] [142945] (1) picpic
          SQ Q96PU4 1-76
      34. Ubiquilin-3 [142946]
        1. Human (Homo sapiens) [TaxId: 9606] [142947] (2) picpic
          SQ Q9H347 11-104! SQ Q9H347 15-98
      35. Ubiquitin-like PHD and RING finger domain-containing protein 1 [142948]
        1. Human (Homo sapiens) [TaxId: 9606] [142949] (2) picpic
          SQ Q96T88 1-76
      36. 4931431F19Rik [142950]
        1. Mouse (Mus musculus) [TaxId: 10090] [142951] (1) picpic
          SQ Q9D4I8 14-96
          structure of the C-terminal UBA domain is also known (PDB 1vej)
      37. Large proline-rich protein BAT3 [142952]
        1. Human (Homo sapiens) [TaxId: 9606] [142953] (1) picpic
          SQ P46379 17-89
      38. Dendritic cell-derived ubiquitin-like protein [142954]
        1. Human (Homo sapiens) [TaxId: 9606] [142955] (1) picpic
          SQ Q8WUN7 149-228
    2. UBX domain [54250] (5)
      Pfam 00789
      1. Fas-associated factor 1, Faf1 [54251]
        1. Human (Homo sapiens) [TaxId: 9606] [54252] (1) picpic
      2. p47 [64221]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [64222] (3) picpic
      3. Hypothetical protein KIAA0794 [117818]
        1. Human (Homo sapiens) [TaxId: 9606] [117819] (1) picpic
          SQ O94888 376-487
      4. UBX domain-containing protein 6 (Reproduction 8) [142956]
        1. Mouse (Mus musculus) [TaxId: 10090] [142957] (1) picpic
          SQ Q9QZ49 182-277
      5. Tether containing UBX domain for GLUT4 (Tug) [142958]
        1. Mouse (Mus musculus) [TaxId: 10090] [142959] (1) picpic
          SQ Q8VBT9 10-85
    3. GABARAP-like [54253] (5)
      intracellular membrane trafficking and fusion proteins
      1. Golgi-associated ATPase enhancer of 16 kD, Gate-16 [54254]
        1. Cow (Bos taurus) [TaxId: 9913] [54255] (1) picpic
      2. GABA(A) receptor associated protein GABARAP [69658]
        1. Human (Homo sapiens) [TaxId: 9606] [69659] (6) picpic
        2. Rat (Rattus norvegicus) [TaxId: 10116] [75360] (1) picpic
      3. Microtubule-associated proteins 1A/1B light chain 3B [110802]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [110803] (4) picpic
          SQ Q62625 4-116
        2. Human (Homo sapiens) [TaxId: 9606] [117820] (3) picpic
          SQ Q9GZQ8
    4. First domain of FERM [54256] (7)
      1. Moesin [54257]
        1. Human (Homo sapiens) [TaxId: 9606] [54258] (3) picpic
          SQ P26038 4-297
      2. Radixin [54259]
        1. Mouse (Mus musculus) [TaxId: 10090] [54260] (20) picpic
      3. Ezrin [82581]
        1. Human (Homo sapiens) [TaxId: 9606] [82582] (1) picpic
      4. Erythroid membrane protein 4.1R [54261]
        1. Human (Homo sapiens) [TaxId: 9606] [54262] (1) picpic
      5. Merlin [69660]
        the neurofibromatosis 2 tumor suppressor protein
        1. Human (Homo sapiens) [TaxId: 9606] [69661] (1) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [75361] (1) picpic
      6. Focal adhesion kinase 1 [142960]
        1. Chicken (Gallus gallus) [TaxId: 9031] [142961] (5) picpic
          SQ Q00944 31-130
    5. Ras-binding domain, RBD [54263] (16)
      contains Pfam 00788 and Pfam 02196
      1. c-Raf1 RBD [54264]
        1. Human (Homo sapiens) [TaxId: 9606] [54265] (3) picpic
        2. Rat (Rattus norvegicus) [TaxId: 10116] [54266] (1) picpic
      2. Ral guanosine-nucleotide exchange factor, RalGDS [54267]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [54268] (2) picpic
        2. Human (Homo sapiens) [TaxId: 9606] [54269] (3) picpic
      3. RalGDS-like factor, Rlf [54270]
        1. Mouse (Mus musculus) [TaxId: 10090] [54271] (1) picpic
      4. Rgl [54272]
        1. Mouse (Mus musculus) [TaxId: 10090] [54273] (1) picpic
      5. Phoshoinositide 3-kinase (PI3K) [54274]
        includes parts of the flanking linkers
        1. Pig (Sus scrofa) [TaxId: 9823] [54275] (5) picpic
        2. Human (Homo sapiens) [TaxId: 9606] [54276] (3) picpic
      6. Protein kinase byr2 [69662]
        1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [69663] (2) picpic
      7. Regulator of G-protein signaling 14, RGS14 [117821]
        1. Mouse (Mus musculus) [TaxId: 10090] [117822] (1) picpic
          SQ P97492 366-456
      8. Growth factor receptor-bound protein 7, GRB-7 [117823]
        1. Human (Homo sapiens) [TaxId: 9606] [117824] (1) picpic
          SQ Q14451 100-186
      9. Rap guanine nucleotide exchange factor 5, RapGEF5 [117825]
        1. Human (Homo sapiens) [TaxId: 9606] [117826] (1) picpic
          SQ Q92565 241-331
      10. Ras association domain-containing protein 8 [142962]
        1. Human (Homo sapiens) [TaxId: 9606] [142963] (1) picpic
          SQ Q8NHQ8 1-83
      11. Afadin [142964]
        1. Mouse (Mus musculus) [TaxId: 10090] [142965] (1) picpic
          SQ Q9QZQ1 246-348
          The FHA domain structure is also known (PDB 1wln)
      12. Phospholipase C-epsilon-1 [142966]
        contains several Ras-binding domains; some are 'hidden' in the sequence
        1. Human (Homo sapiens) [TaxId: 9606] [142967] (4) picpic
          SQ Q9P212 2006-2114! SQ Q9P212 2131-2246! SQ Q9P212 2134-2239
      13. A-Raf proto-oncogene serine/threonine-protein kinase [142968]
        1. Human (Homo sapiens) [TaxId: 9606] [142969] (1) picpic
          SQ P10398 19-91
    6. BM-002-like [75362] (3)
      Pfam 03671; UPF0185; this family comprises small uncharacterized proteins including human protein BM-002
      1. Hypothetical protein zk652.3 [75363]
        1. Caenorhabditis elegans [TaxId: 6239] [75364] (1) picpic
      2. Hypothetical protein 1810045k17 [102788]
        1. Mouse (Mus musculus) [TaxId: 10090] [102789] (1) picpic
      3. Ubiquitin-fold modifier 1 [142970]
        1. Human (Homo sapiens) [TaxId: 9606] [142971] (1) picpic
          SQ P61960 1-83
    7. APG12-like [142972] (1)
      Pfam 04110
      1. Autophagy-related protein 12b (APG12b) [142973]
        1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [142974] (2) picpic
          SQ Q9LVK3 10-93
    8. DIX domain [159926] (1)
      Pfam 00778
      1. Axin 1 [159927]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [159928] (9) picpic
          SQ O70239 745-827
  2. CAD & PB1 domains [54277] (2)
    contain extra helix; similar heterodimerization modes; possibly related to the ubiquitin-like superfamily
    link to SUPERFAMILY database - Superfamily
    1. CAD domain [54278] (5)
      1. Cell death-inducing effector B (CIDE-B), N-terminal domain [54279]
        1. Human (Homo sapiens) [TaxId: 9606] [54280] (1) picpic
      2. Caspase-activated DNase (CAD), DFF40, N-terminal domain [54281]
        1. Mouse (Mus musculus) [TaxId: 10090] [54282] (2) picpic
        2. Human (Homo sapiens) [TaxId: 9606] [64223] (1) picpic
      3. Inhibitor of caspase-activated DNase (ICAD), DFF45, N-terminal domain [54283]
        1. Mouse (Mus musculus) [TaxId: 10090] [54284] (1) picpic
        2. Human (Homo sapiens) [TaxId: 9606] [64224] (1) picpic
    2. PB1 domain [64225] (11)
      Pfam 00564
      forms heterodimers, although not all PB1 domain pairs associate.
      1. Neutrophil cytosol factor 2 (p67phox component of NADPH oxidase) [102790]
        1. Human (Homo sapiens) [TaxId: 9606] [102791] (1) picpic
      2. Neutrophil cytosol factor 4 (p40phox component of NADPH oxidase) [102792]
        1. Human (Homo sapiens) [TaxId: 9606] [102793] (1) picpic
      3. Bud emergence mediator Bemp1 [64226]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64227] (2) picpic
      4. Cell division control protein 24, CDC24, C-terminal domain [89834]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89835] (3) picpic
      5. Protein kinase C, iota type [110804]
        1. Human (Homo sapiens) [TaxId: 9606] [110805] (2) picpic
          SQ P41743 16-98 ! SQ P41743 16-99
      6. Mitogen activated protein kinase kinase 5, Map2k5 [117827]
        1. Mouse (Mus musculus) [TaxId: 10090] [117828] (1) picpic
          SQ Q9D222 7-107
        2. Human (Homo sapiens) [TaxId: 9606] [142975] (2) picpic
          SQ Q13163 4-108
      7. Next to BRCA1 gene 1 protein, NBR1 (KIAA0049) [117829]
        1. Human (Homo sapiens) [TaxId: 9606] [117830] (2) picpic
          SQ Q14596 1-85
      8. Partitioning defective-6 homolog alpha, PAR-6 alpha [117831]
        1. Human (Homo sapiens) [TaxId: 9606] [117832] (1) picpic
          SQ Q9NPB6 14-95
      9. Mitogen-activated protein kinase kinase kinase 2, MEKK 2 [142976]
        1. Human (Homo sapiens) [TaxId: 9606] [142977] (3) picpic
          SQ Q9Y2U5 42-123! SQ Q9Y2U5 43-132
      10. Mitogen-activated protein kinase kinase kinase 3, MEKK 3 [142978]
        1. Human (Homo sapiens) [TaxId: 9606] [142979] (2) picpic
          SQ Q99759 42-123! SQ Q99759 43-122
  3. MoaD/ThiS [54285] (4)
    possible link between the ubiquitin-like and 2Fe-2S ferredoxin-like superfamilies
    link to SUPERFAMILY database - Superfamily
    1. MoaD [54286] (3)
      1. Molybdopterin synthase subunit MoaD [54287]
        1. Escherichia coli [TaxId: 562] [54288] (7) picpic
        2. Pyrococcus furiosus [TaxId: 2261] [110806] (1) picpic
          SQ Q8U3C7
      2. MoaD-related protein, N-terminal domain [102794]
        1. Thermus thermophilus [TaxId: 274] [102795] (1) picpic
    2. ThiS [54289] (5)
      1. Thiamin biosynthesis sulfur carrier protein ThiS [54290]
        1. Escherichia coli [TaxId: 562] [54291] (3) picpic
        2. Bacillus subtilis [TaxId: 1423] [110807] (1) picpic
          SQ O31617
      2. Hypothetical protein MTH1743 [69664]
        probable ThiS homologue
        1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [69665] (1) picpic
      3. Hypothetical protein PF1061 [102796]
        1. Archaeon Pyrococcus furiosus [TaxId: 2261] [102797] (2) picpic
      4. Uncharacterised protein TTHA0675 [159929]
        probable ThiS homologue
        1. Thermus thermophilus [TaxId: 274] [159930] (6) picpic
          SQ Q5SKG8 1-63
    3. C9orf74 homolog [117833] (1)
      1. C9orf74 homolog [117834]
        1. Mouse (Mus musculus) [TaxId: 10090] [117835] (2) picpic
          SQ Q9D2P4 #
    4. HI0395-like [159931] (1)
      Pfam 03658; UPF0125
      1. Hypothetical protein HI0395 [159932]
        NTHI0516
        1. Haemophilus influenzae [TaxId: 727] [159933] (2) picpic
          SQ Q4QNE7 2-78
  4. TGS-like [81271] (2)
    possibly related to the ubiquitin-like and MoaD/ThiS superfamilies; some similarity to the alpha-L RNA-binding motif
    link to SUPERFAMILY database - Superfamily
    1. TGS domain [81270] (2)
      1. Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain [55176]
        1. Escherichia coli [TaxId: 562] [55177] (5) picpic
          SQ P0A8M3
        2. Staphylococcus aureus [TaxId: 1280] [102798] (2) picpic
    2. G domain-linked domain [82583] (3)
      1. YchF GTP-binding protein, C-terminal domain [82584]
        N-terminal domain belongs to the Obg family of GTPases some members of which contain a C-terminal TGS domain
        1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [82585] (1) picpic
        2. Haemophilus influenzae [TaxId: 727] [89836] (1) picpic
          HI0393
      2. GTP-binding protein PH0525 [142980]
        1. Pyrococcus horikoshii [TaxId: 53953] [142981] (1) picpic
          SQ O58261 320-395
  5. 2Fe-2S ferredoxin-like [54292] (2)
    link to SUPERFAMILY database - Superfamily
    1. 2Fe-2S ferredoxin-related [54293] (19)
      1. 2Fe-2S ferredoxin [54294]
        1. Cyanobacterium (Anabaena sp.), pcc 7119 and 7120 [TaxId: 1167] [54295] (12) picpic
        2. Spirulina platensis [TaxId: 118562] [54296] (1) picpic
        3. Cyanobacterium (Aphanothece sacrum) [TaxId: 1122] [54297] (1) picpic
        4. Synechocystis sp., pcc 6803 [TaxId: 1143] [54298] (3) picpic
        5. Synechococcus elongatus [TaxId: 32046] [54299] (3) picpic
        6. Chlorella fusca [TaxId: 3073] [54300] (1) picpic
        7. Equisetum arvense [TaxId: 3258] [54301] (2) picpic
          SQ P00237 # isoform II
        8. Archaeon Haloarcula marismortui [TaxId: 2238] [54302] (1) picpic
        9. Archaeon Halobacterium halobium [TaxId: 2242] [64228] (2) picpic
        10. Parsley (Petroselinum crispum) [TaxId: 4043] [54303] (1) picpic
        11. Spinach (Spinacia oleracea) [TaxId: 3562] [54304] (1) picpic
        12. Maize (Zea mays) [TaxId: 4577] [54305] (1) picpic
        13. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [102799] (1) picpic
        14. Trichomonas vaginalis [TaxId: 5722] [75365] (1) picpic
        15. Rhodobacter capsulatus, ferredoxin VI [TaxId: 1061] [64230] (2) picpic
        16. Pseudomonas putida, putidaredoxin [TaxId: 303] [54307] (18) picpic
        17. Pseudomonas sp., terpredoxin [TaxId: 306] [54309] (1) picpic
      2. Adrenodoxin-like ferredoxin [75366]
        1. Escherichia coli [TaxId: 562] [75367] (1) picpic
      3. Adrenodoxin [54310]
        1. Cow (Bos taurus) [TaxId: 9913] [54311] (7) picpic
    2. 2Fe-2S ferredoxin domains from multidomain proteins [54312] (16)
      1. Fe-only hydrogenase, N-terminal domain [54313]
        1. Clostridium pasteurianum [TaxId: 1501] [54314] (4) picpic
      2. Aldehyde oxidoreductase, N-terminal domain [54315]
        1. Desulfovibrio gigas [TaxId: 879] [54316] (3) picpic
          SQ Q46509
        2. Desulfovibrio desulfuricans [TaxId: 876] [54317] (1) picpic
      3. Xanthine oxidase, N-terminal domain [54318]
        1. Cow (Bos taurus) [TaxId: 9913] [54319] (7) picpic
          SQ P80457
      4. Xanthine dehydrogenase chain A, N-terminal domain [69666]
        1. Rhodobacter capsulatus [TaxId: 1061] [69667] (2) picpic
      5. Carbone monoxide (CO) dehydrogenase iron-sulfur protein, N-domain [54320]
        1. Oligotropha carboxidovorans, formerly Pseudomonas carboxydovorans [TaxId: 40137] [54321] (5) picpic
        2. Hydrogenophaga pseudoflava [TaxId: 47421] [54322] (4) picpic
      6. Phthalate dioxygenase reductase, C-terminal domain [54323]
        two other domains are common to ferredoxin reductase
        1. Pseudomonas cepacia, db01 [TaxId: 292] [54324] (1) picpic
      7. Benzoate dioxygenase reductase, N-terminal domain [75368]
        1. Acinetobacter sp. [TaxId: 472] [75369] (1) picpic
      8. Succinate dehydogenase iron-sulfur protein, N-terminal domain [82586]
        1. Escherichia coli [TaxId: 562] [82587] (3) picpic
      9. Fumarate reductase iron-sulfur protein, N-terminal domain [54325]
        1. Escherichia coli [TaxId: 562] [54326] (7) picpic
        2. Wolinella succinogenes [TaxId: 844] [54327] (8) picpic
      10. Methane monooxygenase reductase N-terminal domain [69668]
        1. Methylococcus capsulatus [TaxId: 414] [69669] (1) picpic
      11. Quinoline 2-oxidoreductase small subunit QorS, N-domain [110808]
        1. Pseudomonas putida [TaxId: 303] [110809] (1) picpic
          SQ P72223
      12. 4-hydroxybenzoyl-CoA reductase gamma subunit HrcC, N-terminal domain [117836]
        1. Thauera aromatica [TaxId: 59405] [117837] (2) picpic
          SQ O33818
      13. Nadh-quinone oxidoreductase chain 3, Nqo3, N-terminal domain [142982]
        1. Thermus thermophilus [TaxId: 274] [142983] (4) picpic
          SQ Q56223 1-95
  6. Staphylokinase/streptokinase [54328] (1)
    link to SUPERFAMILY database - Superfamily
    1. Staphylokinase/streptokinase [54329] (2)
      1. Staphylokinase [54330]
        1. Staphylococcus aureus [TaxId: 1280] [54331] (7) picpic
          phage-borne; Bacteriophage 42D
      2. Streptokinase [54332]
        duplication: consists of three similar domains
        1. Streptococcus equisimilis [TaxId: 119602] [54333] (5) picpic
  7. Doublecortin (DC) [89837] (1)
    possibly related to the ubiquitin-like superfamily
    link to SUPERFAMILY database - Superfamily
    1. Doublecortin (DC) [89838] (2)
      1. Doublecortin-like kinase Dclk [89839]
        KIAA0369; duplication: contains tandem repeat of two DC domains
        1. Human (Homo sapiens) [TaxId: 9606] [89840] (3) picpic
      2. Doublecortin [89841]
        duplication: contains tandem repeat of two DC domains
        1. Human (Homo sapiens) [TaxId: 9606] [89842] (1) picpic
  8. Superantigen toxins, C-terminal domain [54334] (1)
    link to SUPERFAMILY database - Superfamily
    1. Superantigen toxins, C-terminal domain [54335] (15)
      1. Staphylococcal enterotoxin A, SEA [54336]
        1. Staphylococcus aureus [TaxId: 1280] [54337] (6) picpic
      2. Staphylococcal enterotoxin C2, SEC2 [54338]
        1. Staphylococcus aureus [TaxId: 1280] [54339] (8) picpic
      3. Toxic shock syndrome toxin-1 (TSST-1) [54340]
        1. Staphylococcus aureus [TaxId: 1280] [54341] (13) picpic
      4. Staphylococcal enterotoxin B, SEB [54342]
        1. Staphylococcus aureus [TaxId: 1280] [54343] (12) picpic
      5. Staphylococcal enterotoxin C3, SEC3 [54344]
        1. Staphylococcus aureus [TaxId: 1280] [54345] (11) picpic
          SQ P23313
      6. Staphylococcal enterotoxin H, SEH [54346]
        1. Staphylococcus aureus [TaxId: 1280] [54347] (4) picpic
      7. Superantigen-like protein SET3 [75370]
        1. Staphylococcus aureus [TaxId: 1280] [75371] (3) picpic
      8. Streptococcal superantigen Spe-C [54348]
        1. Streptococcus pyogenes [TaxId: 1314] [54349] (3) picpic
      9. Streptococcal superantigen Spe-H [54350]
        1. Streptococcus pyogenes [TaxId: 1314] [54351] (2) picpic
      10. Streptococcal superantigen Smez-2 [54352]
        1. Streptococcus pyogenes [TaxId: 1314] [54353] (2) picpic
      11. Streptococcal superantigen SSA [54354]
        1. Streptococcus pyogenes [TaxId: 1314] [54355] (10) picpic
      12. Streptococcal pyrogenic exotoxin A1 [54356]
        1. Streptococcus pyogenes [TaxId: 1314] [54357] (8) picpic
          SQ P08095
      13. Exotoxin 1 (SET1, Superantigen-like protein 7) [110810]
        1. Staphylococcus aureus [TaxId: 1280] [110811] (2) picpic
          SQ Q9ZFS5 36-231
      14. Streptococcal pyrogenic exotoxin Spe-J [110812]
        1. Streptococcus pyogenes [TaxId: 1314] [110813] (2) picpic
          SQ Q7BAE3
      15. Enterotoxin type I [159934]
        1. Staphylococcus aureus [TaxId: 1280] [159935] (1) picpic
          SQ Q52T95 87-216
  9. Immunoglobulin-binding domains [54358] (1)
    link to SUPERFAMILY database - Superfamily
    1. Immunoglobulin-binding domains [54359] (2)
      1. Immunoglobulin-binding protein G, different constituent domains [54360]
        1. Streptococcus sp., group G [TaxId: 1306] [54361] (30) picpic
      2. Immunoglobulin light chain-binding domain of protein L [54362]
        1. Peptostreptococcus magnus [TaxId: 1260] [54363] (12) picpic
  10. Translation initiation factor IF3, N-terminal domain [54364] (1)
    link to SUPERFAMILY database - Superfamily
    1. Translation initiation factor IF3, N-terminal domain [54365] (1)
      1. Translation initiation factor IF3, N-terminal domain [54366]
        1. Bacillus stearothermophilus [TaxId: 1422] [54367] (1) picpic
  11. Glutamine synthetase, N-terminal domain [54368] (1)
    link to SUPERFAMILY database - Superfamily
    1. Glutamine synthetase, N-terminal domain [54369] (2)
      1. Glutamine synthetase, N-terminal domain [54370]
        1. Salmonella typhimurium [TaxId: 90371] [54371] (18) picpic
        2. Mycobacterium tuberculosis [TaxId: 1773] [75372] (8) picpic
  12. TmoB-like [110814] (1)
    possibly related to the ubiquitin-like and/or 2Fe-2S ferredoxin-like superfamilies
    link to SUPERFAMILY database - Superfamily
    1. TmoB-like [110815] (1)
      Pfam 06234
      1. Toluene, o-xylene monooxygenase oxygenase subunit TouB [110816]
        1. Pseudomonas stutzeri [TaxId: 316] [110817] (6) picpic
          SQ O87799
  13. Nqo1 middle domain-like [142984] (1)
    possibly evolved from 2Fe-2S ferredoxins; contains no iron-sulfur cluster
    link to SUPERFAMILY database - Superfamily
    1. Nqo1 middle domain-like [142985] (1)
      C-terminal part of Pfam 01512
      1. NADH-quinone oxidoreductase chain 1, Nqo1 [142986]
        1. Thermus thermophilus [TaxId: 274] [142987] (4) picpic
          SQ Q56222 250-333
  14. NSP3A-like [159936] (1)
    short helical inserions in the common fold
    1. NSP3A-like [159937] (1)
      1. Nsp3 [159938]
        1. SARS coronavirus [TaxId: 227859] [159939] (2) picpic
          SQ P59641 819-930
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk