Structural Classification of Proteins
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Family: Ras-binding domain, RBD

contains Pfam 00788 and Pfam 02196

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: beta-Grasp (ubiquitin-like) [54235]
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
  4. Superfamily: Ubiquitin-like [54236]
    link to SUPERFAMILY database - Superfamily
  5. Family: Ras-binding domain, RBD [54263]
    contains Pfam 00788 and Pfam 02196

Protein Domains:

  1. c-Raf1 RBD [54264]
    1. Human (Homo sapiens) [TaxId: 9606] [54265] (3) picpic
    2. Rat (Rattus norvegicus) [TaxId: 10116] [54266] (1) picpic
  2. Ral guanosine-nucleotide exchange factor, RalGDS [54267]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [54268] (2) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [54269] (3) picpic
  3. RalGDS-like factor, Rlf [54270]
    1. Mouse (Mus musculus) [TaxId: 10090] [54271] (1) picpic
  4. Rgl [54272]
    1. Mouse (Mus musculus) [TaxId: 10090] [54273] (1) picpic
  5. Phoshoinositide 3-kinase (PI3K) [54274]
    includes parts of the flanking linkers
    1. Pig (Sus scrofa) [TaxId: 9823] [54275] (5) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [54276] (3) picpic
  6. Protein kinase byr2 [69662]
    1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [69663] (2) picpic
  7. Regulator of G-protein signaling 14, RGS14 [117821]
    1. Mouse (Mus musculus) [TaxId: 10090] [117822] (1) picpic
      SQ P97492 366-456
  8. Growth factor receptor-bound protein 7, GRB-7 [117823]
    1. Human (Homo sapiens) [TaxId: 9606] [117824] (1) picpic
      SQ Q14451 100-186
  9. Rap guanine nucleotide exchange factor 5, RapGEF5 [117825]
    1. Human (Homo sapiens) [TaxId: 9606] [117826] (1) picpic
      SQ Q92565 241-331
  10. Ras association domain-containing protein 8 [142962]
    1. Human (Homo sapiens) [TaxId: 9606] [142963] (1) picpic
      SQ Q8NHQ8 1-83
  11. Afadin [142964]
    1. Mouse (Mus musculus) [TaxId: 10090] [142965] (1) picpic
      SQ Q9QZQ1 246-348
      The FHA domain structure is also known (PDB 1wln)
  12. Phospholipase C-epsilon-1 [142966]
    contains several Ras-binding domains; some are 'hidden' in the sequence
    1. Human (Homo sapiens) [TaxId: 9606] [142967] (4) picpic
      SQ Q9P212 2006-2114! SQ Q9P212 2131-2246! SQ Q9P212 2134-2239
  13. A-Raf proto-oncogene serine/threonine-protein kinase [142968]
    1. Human (Homo sapiens) [TaxId: 9606] [142969] (1) picpic
      SQ P10398 19-91
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk