Fold: beta-Grasp (ubiquitin-like)

core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: beta-Grasp (ubiquitin-like) [54235]
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

Superfamilies:

1. Ubiquitin-like [54236] (8)
   uperfamily
2. CAD & PB1 domains [54277] (2)
   contain extra helix; similar heterodimerization modes; possibly related to the ubiquitin-like superfamily
   uperfamily
3. MoaD/ThiS [54285] (4)
   possible link between the ubiquitin-like and 2Fe-2S ferredoxin-like superfamilies
   uperfamily
4. TGS-like [81271] (2)
   possibly related to the ubiquitin-like and MoaD/ThiS superfamilies; some similarity to the alpha-L RNA-binding motif
   uperfamily
5. 2Fe-2S ferredoxin-like [54292] (2)
   uperfamily
6. Staphylokinase/streptokinase [54328] (1)
   uperfamily
7. Doublecortin (DC) [89837] (1)
   possibly related to the ubiquitin-like superfamily
   uperfamily
8. Superantigen toxins, C-terminal domain [54334] (1)
   uperfamily
9. Immunoglobulin-binding domains [54358] (1)
   uperfamily
10. Translation initiation factor IF3, N-terminal domain [54364] (1)
    uperfamily
11. Glutamine synthetase, N-terminal domain [54368] (1)
    uperfamily
12. TmoB-like [110814] (1)
    possibly related to the ubiquitin-like and/or 2Fe-2S ferredoxin-like superfamilies
    uperfamily
13. Nqo1 middle domain-like [142984] (1)
    possibly evolved from 2Fe-2S ferredoxins; contains no iron-sulfur cluster
    uperfamily
14. NSP3A-like [159936] (1)
    short helical inserions in the common fold

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk