Structural Classification of Proteins
Family: SH2 domain
Pfam 00017
Lineage:
Root:
scop
Class:
Alpha and beta proteins (a+b)
[53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold:
SH2-like
[55549]
3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
Superfamily:
SH2 domain
[55550]
uperfamily
Family:
SH2 domain
[55551]
Pfam 00017
Protein Domains:
p56-lck tyrosine kinase [55552]
Human (Homo sapiens)
[TaxId: 9606]
[55553] (16)
Carboxyl-terminal src kinase (csk) [75498]
Human (Homo sapiens)
[TaxId: 9606]
[75499] (1)
c-src tyrosine kinase [55556]
Human (Homo sapiens)
[TaxId: 9606]
[55557] (42)
Chicken (Gallus gallus)
[TaxId: 9031]
[55558] (3)
Rous sarcoma virus
[TaxId: 11886]
[69782] (13)
Tyrosine kinase Fyn [55559]
Human (Homo sapiens)
[TaxId: 9606]
[55560] (3)
Tyrosine phosphatase Syp [55561]
Mouse (Mus musculus)
[TaxId: 10090]
[55562] (4)
Growth factor receptor-bound protein 2 (GRB2) [55563]
Human (Homo sapiens)
[TaxId: 9606]
[55564] (25)
Hemopoetic cell kinase Hck [55565]
Human (Homo sapiens)
[TaxId: 9606]
[55566] (4)
Crk proto-oncogen [82741]
Human (Homo sapiens)
[TaxId: 9606]
[82742] (3)
Shc adaptor protein [55567]
Human (Homo sapiens)
[TaxId: 9606]
[55568] (2)
Phosphatidylinositol 3-kinase, p85-alpha subunit [55569]
Cow (Bos taurus)
[TaxId: 9913]
[55570] (7)
Human (Homo sapiens)
[TaxId: 9606]
[55571] (2)
Rat (Rattus norvegicus)
[TaxId: 10116]
[55572] (2)
Proto-oncogen tyrosine kinase [55573]
Human (Homo sapiens)
[TaxId: 9606]
[55574] (2)
Syk tyrosine kinase [55575]
Human (Homo sapiens)
[TaxId: 9606]
[55576] (3)
Growth factor receptor-bound protein 10, GRB10 [89994]
Human (Homo sapiens)
[TaxId: 9606]
[89995] (1)
Growth factor receptor-bound protein 7 [103135]
Human (Homo sapiens)
[TaxId: 9606]
[103136] (5)
Tyrosine-protein kinase zap-70 [89996]
Human (Homo sapiens)
[TaxId: 9606]
[89997] (3)
Phospholipase C-gamma-1 [55577]
Cow (Bos taurus)
[TaxId: 9913]
[55578] (3)
P55 Blk protein tyrosine kinase [55579]
Mouse (Mus musculus)
[TaxId: 10090]
[55580] (2)
Itk/tsk protein tyrosine kinase [82743]
Mouse (Mus musculus)
[TaxId: 10090]
[82744] (6)
Abl tyrosine kinase [55581]
Human (Homo sapiens)
[TaxId: 9606]
[55582] (1)
Mouse (Mus musculus)
[TaxId: 10090]
[89998] (2)
Csk homologous kinase Chk [64345]
Human (Homo sapiens)
[TaxId: 9606]
[64346] (1)
STAT-1 [55583]
Human (Homo sapiens)
[TaxId: 9606]
[55584] (1)
STAT3b [55585]
Mouse (Mus musculus)
[TaxId: 10090]
[55586] (1)
STAT homologue [103137]
Dictyostelium discoideum
[TaxId: 44689]
[103138] (2)
Cbl [55587]
Human (Homo sapiens)
[TaxId: 9606]
[55588] (12)
Tyrosine phoshatase shp-2 [55589]
Human (Homo sapiens)
[TaxId: 9606]
[55590] (1)
The Xlp protein Sap [55591]
Human (Homo sapiens)
[TaxId: 9606]
[55592] (6)
Ews/fli1 activated transcript 2, Eat2 [89999]
Mouse (Mus musculus)
[TaxId: 10090]
[90000] (1)
Adaptor protein Aps [103139]
Rat (Rattus norvegicus)
[TaxId: 10116]
[103140] (2)
Tyrosine-protein kinase 6 (Breast tumor kinase, Brk) [111084]
Human (Homo sapiens)
[TaxId: 9606]
[111085] (1)
SQ
Q13882
75-174
GRB2-related adaptor protein 2 (MONA, GRID) [111086]
Mouse (Mus musculus)
[TaxId: 10090]
[111087] (3)
SQ
O89100
53-147
Beta-chimaerin, N-terminal domain [118052]
includes N-terminal tail and the linker to the next domain
Human (Homo sapiens)
[TaxId: 9606]
[118053] (1)
SQ
P52757
23-468
Hematopoietic SH2 domain containing protein HSH2D [143623]
Human (Homo sapiens)
[TaxId: 9606]
[143624] (1)
SQ
Q96JZ2
24-129
Suppressor of cytokine signaling 2, SOCS-2 [160562]
Human (Homo sapiens)
[TaxId: 9606]
[160563] (1)
SQ
O14508
32-134
Suppressor of cytokine signaling 4, SOCS-4 [160564]
Human (Homo sapiens)
[TaxId: 9606]
[160565] (1)
SQ
Q8WXH5
274-385
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Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright
© 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk