Structural Classification of Proteins
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Protein: Syk tyrosine kinase from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: SH2-like [55549]
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
  4. Superfamily: SH2 domain [55550]
    link to SUPERFAMILY database - Superfamily
  5. Family: SH2 domain [55551]
    Pfam 00017
  6. Protein: Syk tyrosine kinase [55575]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [55576]

PDB Entry Domains:

  1. 1a81 picpic
    1. region a:9-137 [40507] picpiclink
    2. region a:138-262 [40508] picpiclink
    3. region c:9-137 [40509] picpiclink
    4. region c:138-262 [40510] picpiclink
    5. region e:9-117 [40511] picpiclink
    6. region e:152-262 [40512] picpiclink
    7. region g:9-117 [40513] picpiclink
    8. region g:152-262 [40514] picpiclink
    9. region i:9-137 [40515] picpiclink
    10. region i:138-262 [40516] picpiclink
    11. region k:9-117 [40517] picpiclink
    12. region k:152-262 [40518] picpiclink
  2. 1csy picpic
    C-terminal SH2 domain
    complexed with ace, nh2
    1. chain a [40519] picpiclink
  3. 1csz picpic
    C-terminal SH2 domain
    complexed with ace, nh2
    1. chain a [40520] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk