Structural Classification of Proteins
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Protein: Anthrax toxin lethal factor, N- and C-terminal domains from Bacillus anthracis [TaxId: 1392]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Zincin-like [55485]
    contains mixed beta sheet with connection over free side of the sheet
  4. Superfamily: Metalloproteases ("zincins"), catalytic domain [55486]
    link to SUPERFAMILY database - Superfamily
  5. Family: Anthrax toxin lethal factor, N- and C-terminal domains [69775]
  6. Protein: Anthrax toxin lethal factor, N- and C-terminal domains [69776]
    duplication: each domain adopts a thermolysin-like fold, but the proteolytic activity resides only in the C-terminal domain
  7. Species: Bacillus anthracis [TaxId: 1392] [69777]

PDB Entry Domains:

  1. 1j7n picpicxref
    complexed with so4, zn
    1. region a:27-263 [66409] picpiclink
    2. region a:551-773 [66410] picpiclink
    3. region b:27-263 [66412] picpiclink
    4. region b:551-776 [66413] picpiclink
  2. 1yqy picpicxref
    automatically matched to d1j7nb2
    complexed with 915, zn
    1. region a:551-776 [123903] picpiclink
  3. 1zxv picpicxrefxref
    automatically matched to d1j7na1
    complexed with mfm, zn
    1. region a:27-263 [125797] picpiclink
  4. 1zxv picpicxrefxref
    automatically matched to d1j7nb2
    complexed with mfm, zn
    1. region a:551-776 [125798] picpiclink
  5. 1zxv picpicxrefxref
    automatically matched to d1j7na1
    complexed with mfm, zn
    1. region b:27-263 [125800] picpiclink
  6. 1zxv picpicxrefxref
    automatically matched to d1j7nb2
    complexed with mfm, zn
    1. region b:551-776 [125801] picpiclink
  7. 1pwu picpicxref
    complexed with small molecule inhibitor
    complexed with gm6, zn; mutant
    1. region a:30-263 [95244] picpiclink
    2. region a:551-776 [95245] picpiclink
    3. region b:33-263 [95247] picpiclink
    4. region b:551-776 [95248] picpiclink
  8. 1pwp picpicxref
    complexed with small molecule inhibitor
    complexed with nsc, zn
    1. region a:30-263 [95232] picpiclink
    2. region a:551-776 [95233] picpiclink
    3. region b:31-263 [95235] picpiclink
    4. region b:551-776 [95236] picpiclink
  9. 1pwv picpicxref
    complexed with an optimized peptide substrate (chains C and D) in the presence of zinc
    1. region a:27-263 [95250] picpiclink
    2. region a:551-776 [95251] picpiclink
    3. region b:33-263 [95253] picpiclink
    4. region b:551-776 [95254] picpiclink
  10. 1pww picpicxref
    complexed with an optimized peptide substrate (chains C and D) in the presence of zinc
    complexed with zn; mutant
    1. region a:29-263 [95256] picpiclink
    2. region a:551-776 [95257] picpiclink
    3. region b:28-263 [95259] picpiclink
    4. region b:551-776 [95260] picpiclink
  11. 1pwq picpicxref
    complexed with small molecule inhibitor
    complexed with sd2, zn
    1. region a:27-263 [95238] picpiclink
    2. region a:551-776 [95239] picpiclink
    3. region b:27-263 [95241] picpiclink
    4. region b:551-776 [95242] picpiclink
  12. 1jky picpicxref
    complexed with the n-terminal peptide of mapkk2
    1. region a:29-263 [66817] picpiclink
    2. region a:551-776 [66818] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk