Structural Classification of Proteins
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Superfamily: DHS-like NAD/FAD-binding domain

binds cofactor molecules in the opposite direction than classical Rossmann fold
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: DHS-like NAD/FAD-binding domain [52466]
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. Superfamily: DHS-like NAD/FAD-binding domain [52467]
    binds cofactor molecules in the opposite direction than classical Rossmann fold
    link to SUPERFAMILY database - Superfamily

Families:

  1. Deoxyhypusine synthase, DHS [52468] (1) picpic
  2. C-terminal domain of the electron transfer flavoprotein alpha subunit [52471] (3) picpic
    lacks strand 3; shares the FAD-binding mode with the pyruvate oxidase domain
  3. Pyruvate oxidase and decarboxylase, middle domain [52475] (12) picpic
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  4. Transhydrogenase domain III (dIII) [52484] (3) picpic
    binds NADP, shares with the pyruvate oxidase FAD-binding domain a common ADP-binding mode
  5. Sir2 family of transcriptional regulators [63984] (7) picpic
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. ACDE2-like [142130] (1) picpic
    Pfam 02552
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk