Structural Classification of Proteins
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Protein: Sirt2 histone deacetylase from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: DHS-like NAD/FAD-binding domain [52466]
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. Superfamily: DHS-like NAD/FAD-binding domain [52467]
    binds cofactor molecules in the opposite direction than classical Rossmann fold
    link to SUPERFAMILY database - Superfamily
  5. Family: Sir2 family of transcriptional regulators [63984]
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. Protein: Sirt2 histone deacetylase [63987]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [63988]

PDB Entry Domains:

  1. 1j8f picpic
    complexed with zn
    1. chain a [62738] picpiclink
    2. chain b [62739] picpiclink
    3. chain c [62740] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk