Family: SpoU-like RNA 2'-O ribose methyltransferase

contains extra strand (3) in the parallel beta-sheet, order 321546

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: alpha/beta knot [75216]
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot
4. Superfamily: alpha/beta knot [75217]
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures
   uperfamily
5. Family: SpoU-like RNA 2'-O ribose methyltransferase [75218]
   contains extra strand (3) in the parallel beta-sheet, order 321546

Protein Domains:

1. tRNA (Gm18) methyltransferase TrmH [102279]
   1. Thermus thermophilus [TaxId: 274] [102280] (1)
      1. 1v2x
         complexed with po4, sam
         1. chain a [100274]
2. Hypothetical tRNA/rRNA methyltransfease HI0766 (YibK homologue) [82374]
   1. Haemophilus influenzae [TaxId: 727] [82375] (2)
      1. 1mxi
         complexed with iod, sah
         1. chain a [79646]
      2. 1j85
         1. chain a [77100]
3. RrmA (RrmH), C-terminal domain [75219]
   23S rRNA methyltransferase; proposed gene names are as appear in the original publication (and the PDB entry)
   1. Thermus thermophilus [TaxId: 274] [75220] (1)
      1. 1ipa
         1. region a:106-263 [71254]
4. RlmB, C-terminal domain [82376]
   23S rRNA G2251 2'O-methytransferase
   1. Escherichia coli [TaxId: 562] [82377] (1)
      1. 1gz0
         complexed with mse
         1. region a:78-243 [76391]
         2. region b:78-243 [76393]
         3. region c:78-243 [76395]
         4. region d:78-243 [76397]
         5. region e:78-243 [76399]
         6. region f:78-243 [76400]
         7. region g:78-243 [76402]
         8. region h:78-243 [76403]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk