Structural Classification of Proteins
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Superfamily: alpha/beta knot

known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
all known members have dimeric structures
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: alpha/beta knot [75216]
    core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot
  4. Superfamily: alpha/beta knot [75217]
    known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
    all known members have dimeric structures
    link to SUPERFAMILY database - Superfamily

Families:

  1. YbeA-like [82371] (4) picpic
    Pfam 02590
  2. tRNA(m1G37)-methyltransferase TrmD [89629] (3) picpic
    fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain
  3. SpoU-like RNA 2'-O ribose methyltransferase [75218] (4) picpic
    contains extra strand (3) in the parallel beta-sheet, order 321546
  4. Hypothetical protein MTH1 (MT0001), dimerisation domain [75221] (1) picpic
    contains extra strand (3) in the parallel beta-sheet, order 321546; interrupted by an insert OB-fold domain
  5. YggJ C-terminal domain-like [89632] (3) picpic
    contains extra strand (3) in the parallel beta-sheet, order 321546; similar dimerisation to the MTH1 domain
  6. EMG1/NEP1-like [159513] (2) picpic
    Pfam 03587; structurally most similar to the AF1056-like family, but more decorated
  7. AF1056-like [159518] (2) picpic
    Pfam 04013; DUF358
  8. AF0751-like [159523] (1) picpic
    Pfam 01994; DUF127
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk