Structural Classification of Proteins

Superfamily: FAD/NAD(P)-binding domain

: uperfamily

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: FAD/NAD(P)-binding domain [51904]
core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
Superfamily: FAD/NAD(P)-binding domain [51905]
uperfamily

Families:

C-terminal domain of adrenodoxin reductase-like [51906] (5)
1. Trimethylamine dehydrogenase, C-terminal domain [51907]
  N-terminal domain is beta/alpha barrel and the middle domain is alpha/beta Rossmann-fold
  1. Methylophilus methylotrophus, w3a1 [TaxId: 17] [51908] (5)
    1. 1djq
      1. region a:490-645 [30315]
      2. region b:490-645 [30316]
    2. 1djn
      1. region a:490-645 [30313]
      2. region b:490-645 [30314]
    3. 1o94
      complexed with adp, amp, fmn, sf4
      1. region a:490-645 [81201]
      2. region b:490-645 [81204]
    4. 2tmd
      complexed with adp, fmn, fs4
      1. region a:490-645 [30317]
      2. region b:490-645 [30318]
    5. 1o95
      complexed with adp, amp, fmn, fs4
      1. region a:490-645 [81211]
      2. region b:490-645 [81214]
2. 2,4-dienoyl-CoA reductase, C-terminal domain [102177]
  1. Escherichia coli [TaxId: 562] [102178] (1)
    1. 1ps9
      complexed with cl, fad, fmn, fs4, mde, nap
      1. region a:466-627 [95077]
3. Adrenodoxin reductase of mitochondrial p450 systems [51909]
  1. Cow (Bos taurus) [TaxId: 9913] [51910] (6)
    1. 1cjc
      complexed with fad
      1. region a:107-331 [30319]
    2. 1e1m
      complexed with fad, nap
      1. region a:107-331 [30320]
    3. 1e1k
      complexed with fad, nap
      1. region a:107-331 [30321]
    4. 1e6e
      complexed with fad, fes, so4; mutant
      1. region a:107-331 [59298]
      2. region c:107-331 [59301]
    5. 1e1l
      complexed with fad, nap
      1. region a:107-331 [30322]
    6. 1e1n
      complexed with fad
      1. region a:107-331 [30323]
4. Ferredoxin:NADP reductase FprA [75124]
  1. Mycobacterium tuberculosis [TaxId: 1773] [75125] (2)
    1. 1lqt
      complexed with act, fad, odp
      1. region a:109-324 [74198]
      2. region b:109-324 [74200]
    2. 1lqu
      complexed with act, fad, ndp
      1. region a:109-324 [74202]
      2. region b:109-324 [74204]
5. Dihydropyrimidine dehydrogenase, domain 3 [51911]
  1. Pig (Sus scrofa) [TaxId: 9823] [51912] (5)
    1. 1gte
      complexed with fad, fmn, fs4, iur
      1. region a:288-440 [70442]
      2. region b:288-440 [70447]
      3. region c:288-440 [70452]
      4. region d:288-440 [70457]
    2. 1h7w
      complexed with fad, fmn, fs4
      1. region a:288-440 [30324]
      2. region b:288-440 [30325]
      3. region c:288-440 [30326]
      4. region d:288-440 [30327]
    3. 1h7x
      complexed with fad, fmn, fs4, ndp, urf; mutant
      1. region a:288-440 [30328]
      2. region b:288-440 [30329]
      3. region c:288-440 [30330]
      4. region d:288-440 [30331]
    4. 1gth
      complexed with fad, fmn, fs4, idh, iur, ndp, ura
      1. region a:288-440 [70485]
      2. region b:288-440 [70490]
      3. region c:288-440 [70495]
      4. region d:288-440 [70500]
    5. 1gt8
      complexed with fad, fmn, fs4, ndp, uaa
      1. region a:288-440 [70420]
      2. region b:288-440 [70425]
      3. region c:288-440 [70430]
      4. region d:288-440 [70435]
FAD-linked reductases, N-terminal domain [51913] (25)
C-terminal domain is alpha+beta is common for the family
1. Cholesterol oxidase of GMC family [51914]
  1. Brevibacterium sterolicum [TaxId: 1702] [51915] (2)
    1. 3cox
      complexed with fad
      1. region a:5-318,a:451-506 [30332]
    2. 1coy
      complexed with and, fad
      1. region a:4-318,a:451-506 [30333]
  2. Streptomyces sp. [TaxId: 1931] [51916] (13)
    1. 1n4w
      complexed with fad, gol, mn
      1. region a:9-318,a:451-507 [91676]
    2. 1n1p
      complexed with fad, gol, mn
      1. region a:9-318,a:451-507 [91546]
    3. 1n4u
      complexed with fae, gol, o2, po4
      1. region a:9-318,a:451-507 [91672]
    4. 1mxt
      atomic resolution structure
      complexed with fae, o2, so4
      1. region a:9-318,a:451-507 [79671]
    5. 2gew
      automatically matched to d1ijha1
      complexed with fad, oxy, so4
      1. region a:9-318,a:451-506 [135064]
    6. 3b3r
      automatically matched to d1ijha1
      complexed with fae, gol, so4; mutant
      1. region a:9-318,a:451-506 [154815]
    7. 1n4v
      complexed with fad, gol
      1. region a:9-318,a:451-507 [91674]
    8. 3b6d
      automatically matched to d1ijha1
      complexed with fae, so4; mutant
      1. region a:9-318,a:451-506 [154882]
    9. 1ijh
      complexed with fad; mutant
      1. region a:9-318,a:451-506 [66161]
    10. 1b4v
      complexed with fad
      1. region a:9-318,a:451-506 [30334]
    11. 1b8s
      complexed with fad; mutant
      1. region a:9-318,a:451-506 [30335]
    12. 1cbo
      complexed with fad; mutant
      1. region a:9-318,a:451-506 [30336]
    13. 1cc2
      complexed with fad; mutant
      1. region a:9-318,a:451-506 [30337]
  3. Streptomyces sp. (strain SA-COO) (Streptomyces sp. SA-COO) [TaxId: 74576] [159428] (1)
    1. 3cnj
      automatically matched to d1ijha1
      complexed with fad, so4; mutant
      1. region a:9-318,a:451-506 [156842]
2. Glucose oxidase [51924]
  1. Aspergillus niger [TaxId: 5061] [51925] (2)
    1. 1cf3
      complexed with fad, man, nag
      1. region a:3-324,a:521-583 [30385]
    2. 1gal
      complexed with fad, man, nag
      1. region a:3-324,a:521-583 [30386]
  2. Penicillium amagasakiense [TaxId: 63559] [51926] (1)
    1. 1gpe
      complexed with fad, man, nag
      1. region a:1-328,a:525-587 [30387]
      2. region b:1-328,b:525-587 [30388]
3. Hydroxynitrile lyase [82307]
  1. Almond (Prunus dulcis) [TaxId: 3755] [82308] (1)
    1. 1ju2
      complexed with fad, fuc, ipa, man, nag
      1. region a:1-293,a:464-521 [77169]
      2. region b:1-293,b:464-521 [77171]
4. Flavoprotein domain of flavocytochrome cellobiose dehydrogenase (CDH), FAD-binding domain [82309]
  1. Fungus (Phanerochaete chrysosporium) [TaxId: 5306] [82310] (2)
    1. 1kdg
      complexed with 6fa, emt, hg, man, nag, s
      1. region a:215-512,a:694-755 [77337]
      2. region b:210-512,b:694-755 [77339]
    2. 1naa
      complexed with 6fa, abl, nag
      1. region a:215-512,a:694-755 [80365]
      2. region b:215-512,b:694-755 [80367]
5. p-Hydroxybenzoate hydroxylase, PHBH [51917]
  1. Pseudomonas fluorescens [TaxId: 294] [51918] (17)
    1. 1bgn
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30339]
    2. 1cc4
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30340]
    3. 1pbe
      complexed with fad, phb
      1. region a:1-173,a:276-391 [30338]
    4. 1pdh
      complexed with fas, phb
      1. region a:1-173,a:276-391 [30341]
    5. 1cc6
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30344]
    6. 1pbd
      complexed with fad, pab; mutant
      1. region a:1-173,a:276-391 [30342]
    7. 1bkw
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30343]
    8. 1bf3
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30346]
    9. 1cj4
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-392 [30345]
    10. 1cj3
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-392 [30347]
    11. 1pbb
      complexed with dob, fad; mutant
      1. region a:1-173,a:276-391 [30348]
    12. 1pbf
      complexed with bha, fad; mutant
      1. region a:1-173,a:276-391 [30349]
    13. 1cj2
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30351]
    14. 1pbc
      complexed with bha, fad; mutant
      1. region a:1-173,a:276-391 [30350]
    15. 1bgj
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-391 [30352]
    16. 2phh
      complexed with apr, phb
      1. region a:1-173,a:276-391 [30353]
    17. 1phh
      complexed with dhb, fad
      1. region a:1-173,a:276-394 [30354]
  2. Pseudomonas aeruginosa [TaxId: 287] [51919] (19)
    1. 1k0i
      complexed with fad, phb, so3, so4; mutant
      1. region a:1-173,a:276-394 [67942]
    2. 1iut
      complexed with fad, pab
      1. region a:1-173,a:276-394 [30355]
    3. 1iux
      complexed with fad, phb
      1. region a:1-173,a:276-394 [30358]
    4. 1iuw
      complexed with fad, phb
      1. region a:1-173,a:276-394 [30357]
    5. 1doc
      complexed with br, fad, phb
      1. region a:1-173,a:276-394 [30356]
    6. 1iuu
      complexed with fad, pab
      1. region a:1-173,a:276-394 [30359]
    7. 1k0l
      complexed with fad, so3, so4; mutant
      1. region a:1-173,a:276-394 [67947]
    8. 1dod
      complexed with dob, fad
      1. region a:1-173,a:276-394 [30360]
    9. 1d7l
      1. region a:1-173,a:276-394 [30364]
    10. 1pxc
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-394 [30361]
    11. 1ius
      complexed with fad, pab
      1. region a:1-173,a:276-394 [30363]
    12. 1ykj
      automatically matched to d1d7la1
      complexed with fad, phb, psl, so4; mutant
      1. region a:1001-1173,a:1276-1394 [145914]
    13. 1ykj
      automatically matched to d1d7la1
      complexed with fad, phb, psl, so4; mutant
      1. region b:2001-2173,b:2276-2394 [145916]
    14. 1doe
      complexed with br, dob, fad
      1. region a:1-173,a:276-394 [30365]
    15. 1dob
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-394 [30362]
    16. 1k0j
      complexed with fad, ndp, so4; mutant
      1. region a:1-173,a:276-394 [67944]
    17. 1pxb
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-394 [30367]
    18. 1iuv
      complexed with fad, phb
      1. region a:1-173,a:276-394 [30368]
    19. 1pxa
      complexed with fad, phb; mutant
      1. region a:1-173,a:276-394 [30366]
6. Sarcosine oxidase [51920]
  1. Bacillus sp., strain b0618 [TaxId: 1409] [51921] (18)
    1. 2gf3
      automatically matched to d1l9fb1
      complexed with cl, fad, foa, gol, po4
      1. region a:1-217,a:322-385 [135070]
    2. 2gf3
      automatically matched to d1l9fb1
      complexed with cl, fad, foa, gol, po4
      1. region b:1-217,b:322-385 [135072]
    3. 3bhk
      automatically matched to d1el5a1
      complexed with cl, fad, gol; mutant
      1. region a:1-217,a:322-381 [155271]
    4. 3bhk
      automatically matched to d1el5a1
      complexed with cl, fad, gol; mutant
      1. region b:1-217,b:322-381 [155273]
    5. 1l9e
      complexed with cl, fad, imd
      1. region a:1-217,a:322-385 [77823]
      2. region b:1-217,b:322-385 [77825]
    6. 1el5
      complexed with cl, dmg, fad, po4
      1. region a:1-217,a:322-385 [30369]
      2. region b:1-217,b:322-385 [30370]
    7. 2gb0
      automatically matched to d1l9fb1
      complexed with cl, fad, po4
      1. region a:1-217,a:322-385 [134899]
    8. 2gb0
      automatically matched to d1l9fb1
      complexed with cl, fad, po4
      1. region b:1-217,b:322-385 [134901]
    9. 2a89
      automatically matched to d1l9fb1
      complexed with cl, fcg, po4
      1. region a:1-217,a:322-385 [126393]
    10. 2a89
      automatically matched to d1l9fb1
      complexed with cl, fcg, po4
      1. region b:1-217,b:322-385 [126395]
    11. 1l9c
      complexed with cl, fad, po4; mutant
      1. region a:1-217,a:322-385 [77815]
      2. region b:1-217,b:322-385 [77817]
    12. 1el7
      complexed with cl, fad, mtd, po4, te
      1. region a:1-217,a:322-385 [30371]
      2. region b:1-217,b:322-385 [30372]
    13. 1l9d
      complexed with cl, fad, pyc; mutant
      1. region a:1-217,a:322-385 [77819]
      2. region b:1-217,b:322-385 [77821]
    14. 1el8
      complexed with cl, fad, msf, po4
      1. region a:1-217,a:322-385 [30373]
      2. region b:1-217,b:322-385 [30374]
    15. 1eli
      complexed with cl, fad, po4, pyc
      1. region a:1-217,a:322-385 [30375]
      2. region b:1-217,b:322-385 [30376]
    16. 1el9
      complexed with cl, fad, mtg, po4
      1. region a:1-217,a:322-385 [30377]
      2. region b:1-217,b:322-385 [30378]
    17. 3bhf
      automatically matched to d1el5a1
      complexed with cl, fad; mutant
      1. region a:1-217,a:322-381 [155265]
    18. 3bhf
      automatically matched to d1el5a1
      complexed with cl, fad; mutant
      1. region b:1-217,b:322-381 [155267]
7. Glycine oxidase ThiO [89544]
  1. Bacillus sp. [TaxId: 1409] [89545] (6)
    1. 1ryi
      automatically matched to d1ng3a1
      complexed with fad, goa
      1. region a:1-218,a:307-364 [118813]
    2. 1ryi
      automatically matched to d1ng3a1
      complexed with fad, goa
      1. region b:1-218,b:307-364 [118815]
    3. 1ryi
      automatically matched to d1ng3a1
      complexed with fad, goa
      1. region c:1-218,c:307-364 [118817]
    4. 1ryi
      automatically matched to d1ng3a1
      complexed with fad, goa
      1. region d:1-218,d:307-364 [118819]
    5. 1ng4
      complexed with fad, peo, po4
      1. region a:1-218,a:307-364 [85666]
      2. region b:1-218,b:307-364 [85668]
    6. 1ng3
      complexed with aac, fad, po4
      1. region a:1-218,a:307-364 [85662]
      2. region b:1-218,b:307-364 [85664]
8. Phenol hydroxylase [51922]
  structurally very similar to PHBH, but contains additional C-terminal domain of the thioredoxin-like fold
  1. Soil-living yeast (Trichosporon cutaneum) [TaxId: 5554] [51923] (2)
    1. 1pn0
      complexed with cl, fad, iph
      1. region a:1-240,a:342-461 [94918]
      2. region b:1-240,b:342-461 [94921]
      3. region c:1-240,c:342-461 [94924]
      4. region d:1-240,d:342-461 [94927]
    2. 1foh
      complexed with fad, iph
      1. region a:1-240,a:342-461 [30381]
      2. region b:1-240,b:342-461 [30382]
      3. region c:1-240,c:342-461 [30383]
      4. region d:1-240,d:342-461 [30384]
9. Polyamine oxidase [51927]
  1. Maize (Zea mays) [TaxId: 4577] [51928] (7)
    1. 1b5q
      1. region a:5-293,a:406-463 [30404]
      2. region b:5-293,b:406-466 [30405]
      3. region c:5-293,c:406-466 [30406]
    2. 1h83
      complexed with dia, fad, fca, man, nag
      1. region a:5-293,a:406-463 [30395]
      2. region b:5-293,b:406-466 [30396]
      3. region c:5-293,c:406-466 [30397]
    3. 1b37
      1. region a:5-293,a:406-463 [30389]
      2. region b:5-293,b:406-466 [30390]
      3. region c:5-293,c:406-466 [30391]
    4. 1h82
      complexed with fad, fca, gzz, man, nag
      1. region a:5-293,a:406-463 [30392]
      2. region b:5-293,b:406-466 [30393]
      3. region c:5-293,c:406-466 [30394]
    5. 1h86
      complexed with fad, fca, man, nag, nba
      1. region a:5-293,a:406-463 [30398]
      2. region b:5-293,b:406-466 [30399]
      3. region c:5-293,c:406-466 [30400]
    6. 1h84
      complexed with fad, fca, man, nag, nba
      1. region a:5-293,a:406-463 [30401]
      2. region b:5-293,b:406-466 [30402]
      3. region c:5-293,c:406-466 [30403]
    7. 1h81
      complexed with fad, fca, man, nag
      1. region a:5-293,a:406-463 [30407]
      2. region b:5-293,b:406-466 [30408]
      3. region c:5-293,c:406-466 [30409]
10. L-aminoacid oxidase [51929]
  1. Malayan pit viper (Calloselasma rhodostoma) [TaxId: 8717] [51930] (6)
    1. 2iid
      automatically matched to d1f8ra1
      complexed with fad, fuc, nag, phe
      1. region a:4-319,a:433-486 [137426]
    2. 2iid
      automatically matched to d1f8ra1
      complexed with fad, fuc, nag, phe
      1. region b:4-319,b:433-486 [137428]
    3. 2iid
      automatically matched to d1f8ra1
      complexed with fad, fuc, nag, phe
      1. region c:4-319,c:433-486 [137430]
    4. 2iid
      automatically matched to d1f8ra1
      complexed with fad, fuc, nag, phe
      1. region d:4-319,d:433-486 [137432]
    5. 1f8r
      complexed with cit, fad, fuc, nag
      1. region a:4-319,a:433-486 [30410]
      2. region b:4-319,b:433-486 [30411]
      3. region c:4-319,c:433-486 [30412]
      4. region d:4-319,d:433-486 [30413]
    6. 1f8s
      complexed with be2, fad, nag
      1. region a:5-319,a:433-486 [30414]
      2. region b:5-319,b:433-486 [30415]
      3. region c:5-319,c:433-486 [30416]
      4. region d:5-319,d:433-486 [30417]
      5. region e:5-319,e:433-486 [30418]
      6. region f:5-319,f:433-486 [30419]
      7. region g:5-319,g:433-486 [30420]
      8. region h:5-319,h:433-486 [30421]
  2. Halys viper (Agkistrodon halys) [TaxId: 8714] [102179] (4)
    SQ Q90W54 21-504
    1. 1reo
      complexed with cit, fad, nag
      1. region a:3-319,a:433-486 [97325]
    2. 1tdn
      complexed with fad, leu, nag
      1. region a:3-319,a:433-486 [106777]
    3. 1tdk
      complexed with fad, lvg, nag
      1. region a:3-319,a:433-486 [106775]
    4. 1tdo
      complexed with fad, nag, phe
      1. region a:3-319,a:433-486 [106779]
11. Monoamine oxidase B [69423]
  1. Human (Homo sapiens) [TaxId: 9606] [69424] (20)
    1. 2v5z
      automatically matched to d1o5wc1
      complexed with fad, sag
      1. region a:6-289,a:402-500 [152581]
    2. 2v5z
      automatically matched to d1o5wc1
      complexed with fad, sag
      1. region b:6-289,b:402-496 [152583]
    3. 2v61
      automatically matched to d1o5wc1
      complexed with c18, fad
      1. region a:6-289,a:402-500 [152589]
    4. 2v61
      automatically matched to d1o5wc1
      complexed with c18, fad
      1. region b:6-289,b:402-496 [152591]
    5. 1s3e
      complexed with fad, rhp
      1. region a:3-289,a:402-501 [98426]
      2. region b:3-289,b:402-496 [98428]
    6. 1oja
      complexed with fad, isn
      1. region a:3-289,a:402-501 [93096]
      2. region b:3-289,b:402-496 [93098]
    7. 1s3b
      complexed with fad, rma
      1. region a:3-289,a:402-501 [98422]
      2. region b:3-289,b:402-496 [98424]
    8. 2v60
      automatically matched to d1o5wc1
      complexed with c17, fad
      1. region a:6-289,a:402-500 [152585]
    9. 2v60
      automatically matched to d1o5wc1
      complexed with c17, fad
      1. region b:6-289,b:402-496 [152587]
    10. 1s2q
      complexed with fad, ras
      1. region a:3-289,a:402-501 [98395]
      2. region b:3-289,b:402-496 [98397]
    11. 1s2y
      complexed with fad, rsa
      1. region a:3-289,a:402-501 [98408]
      2. region b:3-289,b:402-496 [98410]
    12. 2vrl
      automatically matched to d1o5wc1
      complexed with fad, mbn
      1. region a:6-289,a:402-500 [153514]
    13. 2vrl
      automatically matched to d1o5wc1
      complexed with fad, mbn
      1. region b:6-289,b:402-496 [153516]
    14. 1ojb
      complexed with 1lp, fad
      1. region a:3-289,a:402-501 [93100]
      2. region b:3-289,b:402-496 [93102]
    15. 2vrm
      automatically matched to d1o5wc1
      complexed with fad, pyl
      1. region a:6-289,a:402-500 [153518]
    16. 2vrm
      automatically matched to d1o5wc1
      complexed with fad, pyl
      1. region b:6-289,b:402-496 [153520]
    17. 1oj9
      complexed with 1pb, fad
      1. region a:3-289,a:402-501 [93092]
      2. region b:3-289,b:402-496 [93094]
    18. 1ojc
      complexed with fad, laz
      1. region a:3-289,a:402-501 [93104]
      2. region b:3-289,b:402-496 [93106]
    19. 1ojd
      complexed with fad, lda
      1. region a:4-289,a:402-500 [93108]
      2. region b:4-289,b:402-497 [93110]
      3. region c:4-289,c:402-501 [93112]
      4. region d:4-289,d:402-497 [93114]
      5. region e:4-289,e:402-501 [93116]
      6. region f:4-289,f:402-500 [93118]
      7. region g:4-289,g:402-497 [93120]
      8. region h:4-289,h:402-501 [93122]
      9. region i:4-289,i:402-500 [93124]
      10. region l:4-289,l:402-500 [93126]
    20. 1gos
      complexed with fad, nyp
      1. region a:4-289,a:402-500 [65425]
      2. region b:4-289,b:402-496 [65427]
  2. Rat (Rattus norvegicus) [TaxId: 10116] [102180] (27)
    1. 2c75
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region a:6-289,a:402-500 [130026]
    2. 2c75
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region b:6-289,b:402-496 [130028]
    3. 2c76
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region a:6-289,a:402-500 [130030]
    4. 2c76
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region b:6-289,b:402-496 [130032]
    5. 2c65
      automatically matched to d1o5wc1
      complexed with 4cr, fad
      1. region a:6-289,a:402-500 [129973]
    6. 2c65
      automatically matched to d1o5wc1
      complexed with 4cr, fad
      1. region b:6-289,b:402-496 [129975]
    7. 2c67
      automatically matched to d1o5wc1
      complexed with fad, rm1
      1. region a:6-289,a:402-500 [129981]
    8. 2c67
      automatically matched to d1o5wc1
      complexed with fad, rm1
      1. region b:6-289,b:402-496 [129983]
    9. 2bk5
      automatically matched to d1o5wc1
      complexed with fad, isn; mutant
      1. region a:6-289,a:402-500 [128656]
    10. 2bk5
      automatically matched to d1o5wc1
      complexed with fad, isn; mutant
      1. region b:6-289,b:402-496 [128658]
    11. 2bk4
      automatically matched to d1o5wc1
      complexed with fad, ras; mutant
      1. region a:6-289,a:402-500 [128652]
    12. 2bk4
      automatically matched to d1o5wc1
      complexed with fad, ras; mutant
      1. region b:6-289,b:402-496 [128654]
    13. 2c72
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region a:6-289,a:402-500 [130018]
    14. 2c72
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region b:6-289,b:402-496 [130020]
    15. 2bk3
      automatically matched to d1o5wc1
      complexed with fad, foh
      1. region a:6-289,a:402-500 [128648]
    16. 2bk3
      automatically matched to d1o5wc1
      complexed with fad, foh
      1. region b:6-289,b:402-496 [128650]
    17. 2c70
      automatically matched to d1o5wc1
      complexed with fad, pnz; mutant
      1. region a:6-289,a:402-500 [130013]
    18. 2c70
      automatically matched to d1o5wc1
      complexed with fad, pnz; mutant
      1. region b:6-289,b:402-496 [130015]
    19. 2c64
      automatically matched to d1o5wc1
      complexed with fad, ma0
      1. region a:6-289,a:402-500 [129969]
    20. 2c64
      automatically matched to d1o5wc1
      complexed with fad, ma0
      1. region b:6-289,b:402-496 [129971]
    21. 2byb
      automatically matched to d1o5wc1
      complexed with dpk, fad
      1. region a:6-289,a:402-500 [129472]
    22. 2byb
      automatically matched to d1o5wc1
      complexed with dpk, fad
      1. region b:6-289,b:402-496 [129474]
    23. 2c73
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region a:6-289,a:402-500 [130022]
    24. 2c73
      automatically matched to d1o5wc1
      complexed with fad, rsa; mutant
      1. region b:6-289,b:402-496 [130024]
    25. 2c66
      automatically matched to d1o5wc1
      complexed with fad, rm2
      1. region a:6-289,a:402-500 [129977]
    26. 2c66
      automatically matched to d1o5wc1
      complexed with fad, rm2
      1. region b:6-289,b:402-496 [129979]
    27. 1o5w
      complexed with fad, mlg
      1. region a:10-298,a:411-520 [92520]
      2. region b:1010-1298,b:1411-1512 [92522]
      3. region c:2010-2298,c:2411-2521 [92524]
      4. region d:3010-3298,d:3411-3515 [92526]
12. N,N-dimethylglycine oxidase [102181]
  1. Arthrobacter globiformis [TaxId: 1665] [102182] (3)
    1. 1pj5
      complexed with act, fad, na
      1. region a:4-219,a:339-427 [94743]
    2. 1pj6
      complexed with fad, fol, na
      1. region a:3-219,a:339-427 [94747]
    3. 1pj7
      complexed with fad, fon, na
      1. region a:4-219,a:339-427 [94751]
13. Protoporphyrinogen oxidase [102183]
  1. Tobacco (Nicotiana tabacum) [TaxId: 4097] [102184] (1)
    1. 1sez
      complexed with fad, omn, ton
      1. region a:13-329,a:442-497 [98822]
      2. region b:13-329,b:442-497 [98824]
  2. Myxococcus xanthus [TaxId: 34] [159429] (4)
    SQ P56601 10-306,415-464
    1. 2ivd
      complexed with acj, fad, gol, twn
      1. region a:10-306,a:415-464 [147805]
    2. 2ivd
      automatically matched to 2IVD A:10-306,A:415-464
      complexed with acj, fad, gol, twn
      1. region b:10-306,b:415-464 [147807]
    3. 2ive
      automatically matched to 2IVD A:10-306,A:415-464
      complexed with fad, gol, twn
      1. region a:10-306,a:415-464 [147809]
    4. 2ive
      automatically matched to 2IVD A:10-306,A:415-464
      complexed with fad, gol, twn
      1. region b:10-306,b:415-464 [147811]
14. Pyranose 2-oxidase [117439]
  1. White-rot fungus (Peniophora sp. SG) [TaxId: 204723] [117440] (19)
    SQ Q8J136 43-619
    1. 2f5v
      automatically matched to d1tzla1
      complexed with fad, kbg, peg, pg4; mutant
      1. region a:43-354,a:553-619 [133010]
    2. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region a:43-354,a:553-619 [137369]
    3. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region b:43-354,b:553-619 [137371]
    4. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region c:43-354,c:553-619 [137373]
    5. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region d:43-354,d:553-619 [137375]
    6. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region e:43-354,e:553-619 [137377]
    7. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region f:43-354,f:553-619 [137379]
    8. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region g:43-354,g:553-619 [137381]
    9. 2ign
      automatically matched to d1tzla1
      complexed with fad, mes; mutant
      1. region h:43-354,h:553-619 [137383]
    10. 2f6c
      automatically matched to d1tzla1
      complexed with fad, peg, pg4; mutant
      1. region a:43-354,a:553-619 [133037]
    11. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region a:43-354,a:553-619 [137385]
    12. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region b:43-354,b:553-619 [137387]
    13. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region c:43-354,c:553-619 [137389]
    14. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region d:43-354,d:553-619 [137391]
    15. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region e:43-354,e:553-619 [137393]
    16. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region f:43-354,f:553-619 [137395]
    17. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region g:43-354,g:553-619 [137397]
    18. 2igo
      automatically matched to d1tzla1
      complexed with fad, g2f; mutant
      1. region h:43-354,h:553-619 [137399]
    19. 1tzl
      complexed with fad
      1. region a:43-354,a:553-619 [112876]
      2. region b:43-354,b:553-619 [112878]
      3. region c:43-354,c:553-619 [112880]
      4. region d:43-354,d:553-619 [112882]
      5. region e:43-354,e:553-619 [112884]
      6. region f:43-354,f:553-619 [112886]
      7. region g:43-354,g:553-619 [112888]
      8. region h:43-354,h:553-619 [112890]
15. Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO [141940]
  1. Pig (Sus scrofa) [TaxId: 9823] [141941] (4)
    SQ P55931 27-259,359-505
    1. 2gmh
      complexed with bhg, edo, fad, na, sf4, uq5
      1. region a:4-236,a:336-482 [135375]
    2. 2gmh
      automatically matched to 2GMH A:4-236,A:336-482
      complexed with bhg, edo, fad, na, sf4, uq5
      1. region b:7-236,b:336-482 [135378]
    3. 2gmj
      automatically matched to 2GMH A:4-236,A:336-482
      complexed with fad, sf4, tbu
      1. region a:4-236,a:336-482 [135383]
    4. 2gmj
      automatically matched to 2GMH A:4-236,A:336-482
      complexed with fad, sf4, tbu
      1. region b:7-236,b:336-482 [135386]
16. Dihydroxypyridine hydroxylase DhpH [159430]
  1. Arthrobacter nicotinovorans [TaxId: 29320] [159431] (3)
    SQ Q93NG3 2-163,292-394
    1. 2vou
      complexed with act, fad, gol; mutant
      1. region a:2-163,a:292-394 [153389]
    2. 2vou
      automatically matched to 2VOU A:2-163,A:292-394
      complexed with act, fad, gol; mutant
      1. region b:2-163,b:292-388 [153391]
    3. 2vou
      automatically matched to 2VOU A:2-163,A:292-394
      complexed with act, fad, gol; mutant
      1. region c:2-163,c:292-388 [153393]
17. Lysine-specific histone demethylase 1, LSD1 [159432]
  1. Human (Homo sapiens) [TaxId: 9606] [159433] (8)
    SQ O60341 274-654,764-836
    1. 2dw4
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with fad
      1. region a:274-654,a:764-831 [146595]
    2. 2z3y
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with f2n
      1. region a:274-654,a:764-831 [154025]
    3. 2z5u
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with fa9
      1. region a:274-654,a:764-831 [154168]
    4. 2iw5
      includes the CoREST-binding subdomain (420-520), a long alpha-helical hairpin
      complexed with cl, fad, gol, nh4
      1. region a:274-654,a:764-836 [145540]
    5. 2ejr
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with f2n
      1. region a:274-654,a:764-831 [146878]
    6. 2uxx
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with cl, fa9, gol
      1. region a:274-654,a:764-835 [152311]
    7. 2uxn
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with cl, fda, gol, lyp
      1. region a:274-654,a:764-836 [145761]
    8. 2h94
      automatically matched to 2IW5 A:274-654,A:764-836
      complexed with fad, hg
      1. region a:274-654,a:764-835 [147246]
18. Monooxygenase PhzS [159434]
  1. Pseudomonas aeruginosa [TaxId: 287] [159435] (1)
    SQ Q9HWG9 4-182,294-402
    1. 3c96
      complexed with fad
      1. region a:4-182,a:294-402 [156122]
GDI-like N domain [51931] (3)
Similar to FAD-linked reductases in both domains but does not bind FAD
1. Guanine nucleotide dissociation inhibitor, GDI [51932]
  the inhibition function is probably associated with an insert subdomain, residues 120-220
  1. Cow (Bos taurus) [TaxId: 9913] [51933] (3)
    1. 1d5t
      complexed with so4
      1. region a:-2-291,a:389-431 [30422]
    2. 1lv0
      complexed with ger, so4
      1. region a:-1-291,a:389-431 [91130]
    3. 1gnd
      1. region a:1-291,a:389-430 [30423]
  2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110439] (13)
    SQ P39958 5-446
    1. 2bcg
      automatically matched to d1ukvg1
      complexed with gdp, ger, mg, trs; mutant
      1. region g:5-301 [128282]
    2. 2bcg
      automatically matched to d1ukvg2
      complexed with gdp, ger, mg, trs; mutant
      1. region g:400-446 [128283]
    3. 1ukv
      complexed with gdp, ger, mg
      1. region g:5-301 [107915]
      2. region g:400-446 [107916]
    4. 3cpi
      automatically matched to d1ukvg1
      1. region g:7-301 [156893]
    5. 3cpi
      automatically matched to d1ukvg2
      1. region g:400-443 [156894]
    6. 3cpi
      automatically matched to d1ukvg1
      1. region h:5-301 [156896]
    7. 3cpi
      automatically matched to d1ukvg2
      1. region h:400-443 [156897]
    8. 3cpj
      automatically matched to d1ukvg1
      complexed with cl, gdp, mg; mutant
      1. region g:6-301 [156899]
    9. 3cpj
      automatically matched to d1ukvg2
      complexed with cl, gdp, mg; mutant
      1. region g:400-443 [156900]
    10. 3cph
      automatically matched to d1ukvg1
      complexed with gdp, mg
      1. region g:5-301 [156887]
    11. 3cph
      automatically matched to d1ukvg2
      complexed with gdp, mg
      1. region g:400-445 [156888]
    12. 3cph
      automatically matched to d1ukvg1
      complexed with gdp, mg
      1. region h:7-301 [156890]
    13. 3cph
      automatically matched to d1ukvg2
      complexed with gdp, mg
      1. region h:400-442 [156891]
2. Rab escort protein 1 [89546]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [89547] (3)
    SQ P37727
    1. 1vg0
      complexed with cl, gdp, ger, mg, pg4; mutant
      1. region a:3-444,a:558-606 [108596]
    2. 1vg9
      complexed with gdp, k, mg, p33; mutant
      1. region a:3-444,a:558-606 [108610]
      2. region c:3-444,c:558-606 [108613]
      3. region e:3-444,e:558-606 [108616]
      4. region g:3-444,g:558-606 [108619]
    3. 1ltx
      complexed with cl, far, zn2; mutant
      1. region r:2-444,r:558-614 [84715]
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain [51934] (7)
1. L-aspartate oxidase [51935]
  1. Escherichia coli [TaxId: 562] [51936] (3)
    1. 1chu
      1. region a:2-237,a:354-422 [30424]
    2. 1knr
      complexed with cl, fad, na; mutant
      1. region a:5-237,a:354-422 [72789]
    3. 1knp
      complexed with fad, na, sin; mutant
      1. region a:5-237,a:354-422 [72784]
2. Succinate dehydogenase [82311]
  1. Escherichia coli [TaxId: 562] [82312] (2)
    1. 1nek
      complexed with ca, cdn, eph, f3s, fad, fes, fs4, hem, oaa, uq2
      1. region a:1-235,a:356-450 [80427]
    2. 1nen
      complexed with ca, cdn, dnt, eph, f3s, fad, fes, fs4, hem, oaa
      1. region a:1-235,a:356-450 [80434]
3. Fumarate reductase [51937]
  1. Escherichia coli [TaxId: 562] [51938] (7)
    1. 1kf6
      complexed with 1pe, act, ce1, f3s, fad, fes, fs4, hqo, k, oaa
      1. region a:0-225,a:358-442 [72395]
      2. region m:0-225,m:358-442 [72402]
    2. 1l0v
      complexed with ce1, f3s, fad, fes, fs4, mq7, oaa
      1. region a:0-225,a:358-442 [73413]
      2. region m:0-225,m:358-442 [73420]
    3. 1kfy
      complexed with brs, ce1, f3s, fad, fes, fs4, oaa
      1. region a:0-225,a:358-442 [72428]
      2. region m:0-225,m:358-442 [72435]
    4. 3cir
      automatically matched to d1kf6a2
      complexed with f3s, fad, fes, sf4; mutant
      1. region a:0-225,a:358-442 [156680]
    5. 3cir
      automatically matched to d1kf6a2
      complexed with f3s, fad, fes, sf4; mutant
      1. region m:0-225,m:358-442 [156687]
    6. 2b76
      automatically matched to d1kf6a2
      complexed with f3s, fad, fes, flc, mq7, sf4; mutant
      1. region a:0-225,a:358-442 [128010]
    7. 2b76
      automatically matched to d1kf6a2
      complexed with f3s, fad, fes, flc, mq7, sf4; mutant
      1. region m:0-225,m:358-442 [128017]
  2. Wolinella succinogenes [TaxId: 844] [51939] (8)
    1. 2bs2
      automatically matched to d1e7pa2
      complexed with f3s, fad, fes, fmr, hem, lmt, na, sf4
      1. region a:1-250,a:372-457 [129031]
    2. 2bs2
      automatically matched to d1e7pa2
      complexed with f3s, fad, fes, fmr, hem, lmt, na, sf4
      1. region d:1-250,d:372-457 [129037]
    3. 2bs3
      automatically matched to d1e7pa2
      complexed with cit, f3s, fad, fes, hem, lmt, na, sf4
      1. region a:1-250,a:372-457 [129043]
    4. 2bs3
      automatically matched to d1e7pa2
      complexed with cit, f3s, fad, fes, hem, lmt, na, sf4
      1. region d:1-250,d:372-457 [129048]
    5. 1qlb
      1. region a:1-250,a:372-457 [30429]
      2. region d:1-250,d:372-457 [30430]
    6. 2bs4
      automatically matched to d1e7pa2
      complexed with cit, dmw, f3s, fad, fes, hem, lmt, na, sf4
      1. region a:1-250,a:372-457 [129053]
    7. 2bs4
      automatically matched to d1e7pa2
      complexed with cit, dmw, f3s, fad, fes, hem, lmt, na, sf4
      1. region d:1-250,d:372-457 [129058]
    8. 1e7p
      complexed with f3s, fad, fes, fs4, hem, lmt, mla, na; mutant
      1. region a:1-250,a:372-457 [59348]
      2. region d:1-250,d:372-457 [59354]
      3. region g:1-250,g:372-457 [59360]
      4. region j:1-250,j:372-457 [59366]
4. Flavocytochrome c3 (respiratory fumarate reductase) [51940]
  contains additional N-terminal multiheme domain
  1. Shewanella frigidimarina [TaxId: 56812] [51941] (16)
    1. 1y0p
      automatically matched to d1qo8a2
      complexed with fad, hem, mez, na
      1. region a:111-361,a:512-568 [122508]
    2. 1q9i
      complexed with fad, hem, na, teo; mutant
      1. region a:103-359,a:506-568 [96274]
    3. 2b7r
      automatically matched to d1qo8a2
      complexed with fad, fum, hem, na; mutant
      1. region a:111-361,a:512-568 [128050]
    4. 1kss
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [72929]
    5. 1m64
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [78684]
      2. region b:103-359,b:506-568 [78687]
    6. 1e39
      complexed with fad, fum, gol, hec, na; mutant
      1. region a:103-359,a:506-568 [30431]
    7. 1ksu
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [72932]
      2. region b:103-359,b:506-568 [72935]
    8. 2b7s
      automatically matched to d1qo8a2
      complexed with fad, fum, hem, na; mutant
      1. region a:111-361,a:512-568 [128053]
    9. 1qjd
      1. region a:103-359,a:506-568 [30432]
    10. 1jry
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [67200]
      2. region b:103-359,b:506-568 [67203]
    11. 1lj1
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [78024]
      2. region b:103-359,b:506-568 [78027]
    12. 1jrz
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [67206]
      2. region b:103-359,b:506-568 [67209]
    13. 1jrx
      complexed with fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [67194]
      2. region b:103-359,b:506-568 [67197]
    14. 1p2e
      complexed with acy, fad, fum, hem, na; mutant
      1. region a:103-359,a:506-568 [93927]
    15. 1p2h
      complexed with fad, hem, na, teo; mutant
      1. region a:103-359,a:506-568 [93931]
    16. 1qo8
      complexed with fad, hem
      1. region a:103-359,a:506-565 [30433]
      2. region d:103-359,d:506-565 [30434]
  2. Shewanella putrefaciens [TaxId: 24] [51942] (3)
    1. 1d4d
      1. region a:103-359,a:506-569 [30439]
    2. 1d4c
      1. region a:103-359,a:506-570 [30435]
      2. region b:103-359,b:506-570 [30436]
      3. region c:103-359,c:506-570 [30437]
      4. region d:103-359,d:506-570 [30438]
    3. 1d4e
      1. region a:103-359,a:506-569 [30440]
5. Adenylylsulfate reductase A subunit [69425]
  1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [69426] (2)
    1. 1jnr
      complexed with fad, fs4, gol
      1. region a:2-256,a:402-502 [66967]
      2. region c:2-256,c:402-502 [66971]
    2. 1jnz
      complexed with fad, fs4, so3
      1. region a:2-256,a:402-502 [71767]
      2. region c:2002-2256,c:2402-2502 [71771]
FAD/NAD-linked reductases, N-terminal and central domains [51943] (28)
duplication: both domains have similar folds and functions
most members of the family contain common C-terminal alpha+beta domain
1. Glutathione reductase [51944]
  1. Human (Homo sapiens) [TaxId: 9606] [51945] (17)
    1. 3grs
      complexed with fad
      1. region a:18-165,a:291-363 [30441]
      2. region a:166-290 [30442]
    2. 1dnc
      complexed with fad, gtt, po4
      1. region a:18-165,a:291-363 [30443]
      2. region a:166-290 [30444]
    3. 1gsn
      complexed with fad, gtt, po4
      1. region a:18-165,a:291-363 [30445]
      2. region a:166-290 [30446]
    4. 1xan
      complexed with fad, hxp
      1. region a:18-165,a:291-363 [30449]
      2. region a:166-290 [30450]
    5. 1grb
      complexed with fad, nad, ndp, po4
      1. region a:18-165,a:291-363 [30447]
      2. region a:166-290 [30448]
    6. 1gra
      complexed with fad, gsh, ndp
      1. region a:18-165,a:291-363 [30451]
      2. region a:166-290 [30452]
    7. 1k4q
      complexed with fad, niy
      1. region a:18-165,a:291-363 [68140]
      2. region a:166-290 [68141]
    8. 1gre
      complexed with fad, gsh, po4
      1. region a:18-165,a:291-363 [30453]
      2. region a:166-290 [30454]
    9. 1grg
      complexed with cec, fad, po4
      1. region a:18-165,a:291-363 [30455]
      2. region a:166-290 [30456]
    10. 1grf
      complexed with cnm, fad, po4
      1. region a:18-165,a:291-363 [30457]
      2. region a:166-290 [30458]
    11. 1bwc
      complexed with aj3, cl, fad
      1. region a:18-165,a:291-363 [30459]
      2. region a:166-290 [30460]
    12. 4gr1
      complexed with fad, po4, rgs
      1. region a:18-165,a:291-363 [30461]
      2. region a:166-290 [30462]
    13. 5grt
      complexed with fad, ts4; mutant
      1. region a:18-165,a:291-363 [30465]
      2. region a:166-290 [30466]
    14. 3grt
      complexed with fad, ts2; mutant
      1. region a:18-165,a:291-363 [30463]
      2. region a:166-290 [30464]
    15. 1grt
      complexed with fad; mutant
      1. region a:17-165,a:291-363 [30467]
      2. region a:166-290 [30468]
    16. 2grt
      complexed with fad, gds; mutant
      1. region a:18-165,a:291-363 [30469]
      2. region a:166-290 [30470]
    17. 4grt
      complexed with fad, ts3; mutant
      1. region a:18-165,a:291-363 [30471]
      2. region a:166-290 [30472]
  2. Plasmodium falciparum [TaxId: 5833] [89548] (1)
    1. 1onf
      complexed with fad
      1. region a:1-153,a:271-376 [87141]
      2. region a:154-270 [87142]
  3. Escherichia coli [TaxId: 562] [51946] (4)
    1. 1ges
      complexed with fad; mutant
      1. region a:3-146,a:263-335 [30473]
      2. region a:147-262 [30474]
      3. region b:2-146,b:263-335 [30475]
      4. region b:147-262 [30476]
    2. 1ger
      complexed with fad
      1. region a:3-146,a:263-335 [30477]
      2. region a:147-262 [30478]
      3. region b:2-146,b:263-335 [30479]
      4. region b:147-262 [30480]
    3. 1get
      complexed with fad, nap
      1. region a:3-146,a:263-335 [30481]
      2. region a:147-262 [30482]
      3. region b:2-146,b:263-335 [30483]
      4. region b:147-262 [30484]
    4. 1geu
      complexed with fad, nad; mutant
      1. region a:3-146,a:263-335 [30485]
      2. region a:147-262 [30486]
      3. region b:2-146,b:263-335 [30487]
      4. region b:147-262 [30488]
2. Trypanothione reductase [51947]
  1. Crithidia fasciculata [TaxId: 5656] [51948] (6)
    1. 1fec
      complexed with fad
      1. region a:1-169,a:287-357 [30489]
      2. region a:170-286 [30490]
      3. region b:2-169,b:287-357 [30491]
      4. region b:170-286 [30492]
    2. 1feb
      complexed with fad
      1. region a:1-169,a:287-357 [30493]
      2. region a:170-286 [30494]
      3. region b:1-169,b:287-357 [30495]
      4. region b:170-286 [30496]
    3. 1fea
      complexed with fad
      1. region a:1-169,a:287-357 [30497]
      2. region a:170-286 [30498]
      3. region b:1-169,b:287-357 [30499]
      4. region b:170-286 [30500]
      5. region c:1-169,c:287-357 [30501]
      6. region c:170-286 [30502]
      7. region d:1-169,d:287-357 [30503]
      8. region d:170-286 [30504]
    4. 2tpr
      complexed with fad
      1. region a:1-168,a:286-357 [30505]
      2. region a:169-285 [30506]
      3. region b:1-168,b:286-357 [30507]
      4. region b:169-285 [30508]
    5. 1typ
      complexed with fad, gsh, nap, spd
      1. region a:1-169,a:287-358 [30509]
      2. region a:170-286 [30510]
      3. region b:2-169,b:287-358 [30511]
      4. region b:170-286 [30512]
    6. 1tyt
      complexed with fad
      1. region a:1-169,a:287-358 [30513]
      2. region a:170-286 [30514]
      3. region b:2-169,b:287-358 [30515]
      4. region b:170-286 [30516]
  2. Trypanosoma cruzi [TaxId: 5693] [51949] (8)
    1. 1aog
      complexed with fad, mae
      1. region a:3-169,a:287-357 [30517]
      2. region a:170-286 [30518]
      3. region b:5-169,b:287-357 [30519]
      4. region b:170-286 [30520]
    2. 1bzl
      1. region a:2-169,a:287-357 [30521]
      2. region a:170-286 [30522]
      3. region b:5-169,b:287-357 [30523]
      4. region b:170-286 [30524]
    3. 1gxf
      complexed with fad, mae, qum
      1. region a:4-169,a:287-357 [90527]
      2. region a:170-286 [90528]
      3. region b:5-169,b:287-357 [90530]
      4. region b:170-286 [90531]
    4. 1nda
      complexed with fad
      1. region a:4-169,a:287-357 [30525]
      2. region a:170-286 [30526]
      3. region b:4-169,b:287-357 [30527]
      4. region b:170-286 [30528]
    5. 1nda
      duplicate of 1NDA A:170-286
      complexed with fad
      1. region c:170-286 [118564]
    6. 1nda
      duplicate of 1NDA A:170-286
      complexed with fad
      1. region d:170-286 [118567]
    7. 1nda
      duplicate of 1NDA A:4-169,A:287-357
      complexed with fad
      1. region c:4-169,c:287-357 [118565]
    8. 1nda
      duplicate of 1NDA A:4-169,A:287-357
      complexed with fad
      1. region d:4-169,d:287-357 [118568]
3. Mammalian thioredoxin reductase [63947]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [63948] (1)
    1. 1h6v
      complexed with fad, ndp; mutant
      1. region a:10-170,a:293-366 [60693]
      2. region a:171-292 [60694]
      3. region b:9-170,b:293-366 [60696]
      4. region b:171-292 [60697]
      5. region c:14-170,c:293-366 [60699]
      6. region c:171-292 [60700]
      7. region d:9-170,d:293-366 [60702]
      8. region d:171-292 [60703]
      9. region e:9-170,e:293-366 [60705]
      10. region e:171-292 [60706]
      11. region f:10-170,f:293-366 [60708]
      12. region f:171-292 [60709]
4. Thioredoxin reductase [51950]
  lacks the "interface" C-terminal alpha+beta domain
  1. Escherichia coli [TaxId: 562] [51951] (5)
    1. 1trb
      complexed with fad; mutant
      1. region a:1-118,a:245-316 [30529]
      2. region a:119-244 [30530]
    2. 1tde
      complexed with fad
      1. region a:1-118,a:245-316 [30531]
      2. region a:119-244 [30532]
    3. 1tdf
      complexed with fad, nap; mutant
      1. region a:1-118,a:245-316 [30533]
      2. region a:119-244 [30534]
    4. 1cl0
      1. region a:1-118,a:245-317 [30535]
      2. region a:119-244 [30536]
    5. 1f6m
      complexed with thioredoxin
      complexed with 3aa, fad; mutant
      1. region a:1-118,a:245-320 [30537]
      2. region a:119-244 [30538]
      3. region b:1-118,b:245-320 [30539]
      4. region b:119-244 [30540]
      5. region e:1-118,e:245-320 [30541]
      6. region e:119-244 [30542]
      7. region f:1-118,f:245-320 [30543]
      8. region f:119-244 [30544]
  2. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [51952] (1)
    1. 1vdc
      complexed with fad, so4
      1. region a:1-117,a:244-316 [30545]
      2. region a:118-243 [30546]
5. Apoptosis-inducing factor (AIF) [75126]
  1. Human (Homo sapiens) [TaxId: 9606] [75127] (1)
    1. 1m6i
      complexed with fad
      1. region a:128-263,a:401-477 [74533]
      2. region a:264-400 [74534]
  2. Mouse (Mus musculus) [TaxId: 10090] [75128] (1)
    1. 1gv4
      complexed with fad
      1. region a:121-264,a:398-477 [70589]
      2. region a:265-397 [70590]
      3. region b:121-264,b:398-477 [70592]
      4. region b:265-397 [70593]
6. Alkyl hydroperoxide reductase subunit F (AhpF), C-terminal domains [51953]
  1. Salmonella typhimurium [TaxId: 90371] [51954] (1)
    1. 1hyu
      complexed with cl, fad, so4
      1. region a:199-325,a:452-521 [30547]
      2. region a:326-451 [30548]
  2. Escherichia coli [TaxId: 562] [63949] (1)
    1. 1fl2
      Catalytic core component only
      complexed with fad, so4
      1. region a:212-325,a:452-521 [59869]
      2. region a:326-451 [59870]
7. NADH peroxidase [51955]
  1. Enterococcus faecalis [TaxId: 1351] [51956] (8)
    1. 1nhp
      complexed with fad, so4; mutant
      1. region a:1-119,a:243-321 [30549]
      2. region a:120-242 [30550]
    2. 1nhs
      complexed with cyo, fad, so4; mutant
      1. region a:1-119,a:243-321 [30555]
      2. region a:120-242 [30556]
    3. 1nhq
      complexed with fad, so4; mutant
      1. region a:1-119,a:243-321 [30551]
      2. region a:120-242 [30552]
    4. 1nhr
      complexed with fad, so4; mutant
      1. region a:1-119,a:243-321 [30553]
      2. region a:120-242 [30554]
    5. 1npx
      complexed with cyo, fad
      1. region a:1-119,a:243-321 [30557]
      2. region a:120-242 [30558]
    6. 2npx
      complexed with cyo, fad, nad
      1. region a:1-119,a:243-321 [30559]
      2. region a:120-242 [30560]
    7. 1f8w
      complexed with fad; mutant
      1. region a:1-119,a:243-321 [30561]
      2. region a:120-242 [30562]
    8. 1joa
      complexed with fad
      1. region a:1-119,a:243-321 [30563]
      2. region a:120-242 [30564]
8. NADH-dependent ferredoxin reductase, BphA4 [51957]
  1. Pseudomonas sp., KKS102 [TaxId: 306] [51958] (2)
    1. 1d7y
      complexed with fad
      1. region a:5-115,a:237-308 [30565]
      2. region a:116-236 [30566]
    2. 1f3p
      complexed with fad, nad
      1. region a:5-115,a:237-308 [59632]
      2. region a:116-236 [59633]
9. Putidaredoxin reductase [102185]
  1. Pseudomonas putida [TaxId: 303] [102186] (2)
    1. 1q1r
      complexed with fad
      1. region a:2-114,a:248-319 [95600]
      2. region a:115-247 [95601]
      3. region b:2-114,b:248-319 [95603]
      4. region b:115-247 [95604]
    2. 1q1w
      complexed with fad
      1. region a:2-114,a:248-319 [95609]
      2. region a:115-247 [95610]
      3. region b:3-114,b:248-319 [95612]
      4. region b:115-247 [95613]
10. Dihydrolipoamide dehydrogenase [51959]
  1. Pseudomonas putida [TaxId: 303] [51960] (1)
    1. 1lvl
      complexed with fad, nad
      1. region a:1-150,a:266-335 [30567]
      2. region a:151-265 [30568]
  2. Pseudomonas fluorescens [TaxId: 294] [51961] (1)
    1. 1lpf
      complexed with fad
      1. region a:1-158,a:278-348 [30569]
      2. region a:159-277 [30570]
      3. region b:1-158,b:278-348 [30571]
      4. region b:159-277 [30572]
  3. Azotobacter vinelandii [TaxId: 354] [51962] (1)
    1. 3lad
      complexed with fad
      1. region a:1-158,a:278-348 [30573]
      2. region a:159-277 [30574]
      3. region b:1-158,b:278-348 [30575]
      4. region b:159-277 [30576]
  4. Bacillus stearothermophilus [TaxId: 1422] [51963] (1)
    1. 1ebd
      complexed with fad
      1. region a:7-154,a:272-346 [30577]
      2. region a:155-271 [30578]
      3. region b:7-154,b:272-346 [30579]
      4. region b:155-271 [30580]
  5. Neisseria meningitidis [TaxId: 487] [51964] (2)
    1. 1ojt
      complexed with fad
      1. region a:117-275,a:401-470 [30581]
      2. region a:276-400 [30582]
    2. 1bhy
      complexed with fad
      1. region a:117-275,a:401-470 [30583]
      2. region a:276-400 [30584]
  6. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [63950] (5)
    1. 1v59
      automatically matched to d1jeha1
      complexed with fad, nad, po4
      1. region a:1-160,a:283-355 [119838]
    2. 1v59
      automatically matched to d1jeha2
      complexed with fad, nad, po4
      1. region a:161-282 [119839]
    3. 1v59
      automatically matched to d1jeha1
      complexed with fad, nad, po4
      1. region b:1-160,b:283-355 [119841]
    4. 1v59
      automatically matched to d1jeha2
      complexed with fad, nad, po4
      1. region b:161-282 [119842]
    5. 1jeh
      complexed with fad
      1. region a:1-160,a:283-355 [62912]
      2. region a:161-282 [62913]
      3. region b:1-160,b:283-355 [62915]
      4. region b:161-282 [62916]
  7. Garden pea (Pisum sativum) [TaxId: 3888] [51965] (1)
    1. 1dxl
      complexed with fad
      1. region a:4-152,a:276-347 [30585]
      2. region a:153-275 [30586]
      3. region b:4-152,b:276-347 [30587]
      4. region b:153-275 [30588]
      5. region c:4-152,c:276-347 [30589]
      6. region c:153-275 [30590]
      7. region d:4-152,d:276-347 [30591]
      8. region d:153-275 [30592]
  8. Mycobacterium tuberculosis [TaxId: 1773] [117441] (1)
    SQ O53355
    1. 1xdi
      complexed with fad
      1. region a:2-161,a:276-348 [115160]
      2. region b:2-161,b:276-348 [115162]
11. NADH-dependent 2-ketopropyl coenzyme M oxidoreductase/carboxylase [82313]
  1. Xanthobacter sp., py2 [TaxId: 35809] [82314] (10)
    1. 1mo9
      complexed with fad, kpc
      1. region a:2-192,a:314-383 [79341]
      2. region a:193-313 [79342]
      3. region b:2-192,b:314-383 [79344]
      4. region b:193-313 [79345]
    2. 2c3c
      automatically matched to d1mo9a1
      complexed with acn, com, fad, nap
      1. region a:2-192,a:314-383 [129725]
    3. 2c3c
      automatically matched to d1mo9a2
      complexed with acn, com, fad, nap
      1. region a:193-313 [129726]
    4. 2c3c
      automatically matched to d1mo9a1
      complexed with acn, com, fad, nap
      1. region b:2-192,b:314-383 [129728]
    5. 2c3c
      automatically matched to d1mo9a2
      complexed with acn, com, fad, nap
      1. region b:193-313 [129729]
    6. 2c3d
      automatically matched to d1mo9a1
      complexed with com, fad
      1. region a:2-192,a:314-383 [129731]
    7. 2c3d
      automatically matched to d1mo9a2
      complexed with com, fad
      1. region a:193-313 [129732]
    8. 2c3d
      automatically matched to d1mo9a1
      complexed with com, fad
      1. region b:2-192,b:314-383 [129734]
    9. 2c3d
      automatically matched to d1mo9a2
      complexed with com, fad
      1. region b:193-313 [129735]
    10. 1mok
      complexed with fad
      1. region a:2-192,a:314-383 [79347]
      2. region a:193-313 [79348]
      3. region b:2-192,b:314-383 [79350]
      4. region b:193-313 [79351]
      5. region c:2-192,c:314-383 [79353]
      6. region c:193-313 [79354]
      7. region d:2-192,d:314-383 [79356]
      8. region d:193-313 [79357]
12. Flavocytochrome c sulfide dehydrogenase, FCSD, flavin-binding subunit [51966]
  has a smaller C-terminal alpha+beta domain instead the "interface" domain
  1. Purple phototrophic bacterium (Chromatium vinosum) [TaxId: 1049] [51967] (1)
    1. 1fcd
      complexed with fad, hem
      1. region a:1-114,a:256-327 [30593]
      2. region a:115-255 [30594]
      3. region b:1-114,b:256-327 [30595]
      4. region b:115-255 [30596]
13. Phenylacetone monooxygenase [110440]
  1. Thermobifida fusca [TaxId: 2021] [110441] (1)
    SQ Q5YS95 # 55% sequence identity; Nocardia farcinica TaxID:37329
    1. 1w4x
      complexed with fad, so4
      1. region a:10-154,a:390-542 [109171]
      2. region a:155-389 [109172]
14. NADH oxidase /nitrite reductase [117442]
  1. Pyrococcus furiosus [TaxId: 2261] [117443] (1)
    SQ Q8U1K9
    1. 1xhc
      Structural genomics target
      complexed with fad
      1. region a:1-103,a:226-289 [115292]
      2. region a:104-225 [115293]
15. Flavin-dependent monoxygenase SPBP16F5.08c [117444]
  1. Schizosaccharomyces pombe [TaxId: 4896] [117445] (13)
    SQ Q9HFE4
    1. 2gvc
      automatically matched to d1vqwa1
      complexed with fad, gol, mmz, peo
      1. region a:3-180,a:288-444 [135763]
    2. 2gvc
      automatically matched to d1vqwa2
      complexed with fad, gol, mmz, peo
      1. region a:181-287 [135764]
    3. 2gvc
      automatically matched to d1vqwa1
      complexed with fad, gol, mmz, peo
      1. region b:3-180,b:288-444 [135765]
    4. 2gvc
      automatically matched to d1vqwa2
      complexed with fad, gol, mmz, peo
      1. region b:181-287 [135766]
    5. 2gvc
      automatically matched to d1vqwa1
      complexed with fad, gol, mmz, peo
      1. region d:3-180,d:288-444 [135767]
    6. 2gvc
      automatically matched to d1vqwa2
      complexed with fad, gol, mmz, peo
      1. region d:181-287 [135768]
    7. 2gvc
      automatically matched to d1vqwa1
      complexed with fad, gol, mmz, peo
      1. region e:3-180,e:288-444 [135769]
    8. 2gvc
      automatically matched to d1vqwa2
      complexed with fad, gol, mmz, peo
      1. region e:181-287 [135770]
    9. 2gv8
      automatically matched to d1vqwa1
      complexed with fad, gol, ndp
      1. region a:3-180,a:288-444 [135759]
    10. 2gv8
      automatically matched to d1vqwa2
      complexed with fad, gol, ndp
      1. region a:181-287 [135760]
    11. 2gv8
      automatically matched to d1vqwa1
      complexed with fad, gol, ndp
      1. region b:3-180,b:288-444 [135761]
    12. 2gv8
      automatically matched to d1vqwa2
      complexed with fad, gol, ndp
      1. region b:181-287 [135762]
    13. 1vqw
      Structural genomics target
      complexed with epe, fad
      1. region a:3-180,a:288-444 [114028]
      2. region a:181-287 [114029]
      3. region b:3-180,b:288-444 [114030]
      4. region b:181-287 [114031]
Thi4-like [141942] (2)
Pfam 01946; stand-alone, moderately decorated domain
1. Thiazole biosynthetic enzyme Thi4 [141943]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141944] (2)
    SQ P32318 16-326
    mitochondrial
    1. 2gjc
      complexed with ahz
      1. region a:16-326 [135280]
    2. 2gjc
      automatically matched to 2GJC A:16-326
      complexed with ahz
      1. region b:16-326 [135281]
  2. Thale cress(Arabidopsis thaliana) [TaxId: 3702] [141945] (1)
    SQ Q38814 51-328
    chloroplast
    1. 1rp0
      complexed with ahz, hto, zn
      1. region a:7-284 [118782]
GidA-like [141946] (1)
part of Pfam 01266
1. GidA-related protein TTHA1897 [141947]
  1. Thermus thermophilus [TaxId: 274] [141948] (1)
    SQ Q5SH33 2-231
    1. 2cul
      complexed with fad
      1. region a:2-231 [130813]
HI0933 N-terminal domain-like [159436] (2)
N-terminal part of Pfam 03486
1. Hypothetical protein HI0933 [159437]
  1. Haemophilus influenzae [TaxId: 727] [159438] (1)
    SQ P44941 1-194,343-401
    1. 2gqf
      complexed with fad, so4
      1. region a:1-194,a:343-401 [147157]
2. Flavoprotein BC4706 [159439]
  1. Bacillus cereus [TaxId: 1396] [159440] (1)
    SQ Q816V9 1-192,362-420
    1. 2i0z
      complexed with cl, fad; mutant
      1. region a:1-192,a:362-420 [147483]