Structural Classification of Proteins
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Protein: Lysine-specific histone demethylase 1, LSD1 from Human (Homo sapiens) [TaxId: 9606]

SQ O60341 274-654,764-836

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: FAD/NAD(P)-binding domain [51904]
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. Superfamily: FAD/NAD(P)-binding domain [51905]
    link to SUPERFAMILY database - Superfamily
  5. Family: FAD-linked reductases, N-terminal domain [51913]
    C-terminal domain is alpha+beta is common for the family
  6. Protein: Lysine-specific histone demethylase 1, LSD1 [159432]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [159433]
    SQ O60341 274-654,764-836

PDB Entry Domains:

  1. 2dw4 picpicxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with fad
    1. region a:274-654,a:764-831 [146595] picpiclink
  2. 2z3y picpicxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with f2n
    1. region a:274-654,a:764-831 [154025] picpiclink
  3. 2z5u picpicxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with fa9
    1. region a:274-654,a:764-831 [154168] picpiclink
  4. 2iw5 picpicxrefxrefxref
    includes the CoREST-binding subdomain (420-520), a long alpha-helical hairpin
    complexed with cl, fad, gol, nh4
    1. region a:274-654,a:764-836 [145540] picpiclink
  5. 2ejr picpicxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with f2n
    1. region a:274-654,a:764-831 [146878] picpiclink
  6. 2uxx picpicxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with cl, fa9, gol
    1. region a:274-654,a:764-835 [152311] picpiclink
  7. 2uxn picpicxrefxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with cl, fda, gol, lyp
    1. region a:274-654,a:764-836 [145761] picpiclink
  8. 2h94 picpicxrefxref
    automatically matched to 2IW5 A:274-654,A:764-836
    complexed with fad, hg
    1. region a:274-654,a:764-835 [147246] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk