Family: FMN-linked oxidoreductases

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: TIM beta/alpha-barrel [51350]
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites
4. Superfamily: FMN-linked oxidoreductases [51395]
   uperfamily
5. Family: FMN-linked oxidoreductases [51396]

Protein Domains:

1. Dihydroorotate dehydrogenase [51397]
   1. Lactococcus lactis, isozyme A [TaxId: 1358] [51398] (13)
   2. Lactococcus lactis, isozyme B [TaxId: 1358] [51399] (3)
      PyrD subunit
   3. Escherichia coli [TaxId: 562] [82239] (1)
   4. Human (Homo sapiens) [TaxId: 9606] [51400] (11)
   5. Rat (Rattus norvegicus) [TaxId: 10116] [102039] (2)
   6. Trypanosoma brucei [TaxId: 5691] [141758] (4)
      SQ Q57U83 2-313
   7. Plasmodium falciparum [TaxId: 5833] [141759] (1)
      SQ Q08210 158-566
      homolog, mitochonrial
2. Old yellow enzyme (OYE) [51401]
   1. Lager yeast (Saccharomyces pastorianus) [TaxId: 27292] [51402] (5)
   2. Yeast (Candida albicans) [TaxId: 5476] [51403] (2)
3. 12-oxophytodienoate reductase (OPR, OYE homolog) [63896]
   1. Tomato (Lycopersicon esculentum), OPR1 [TaxId: 4081] [63897] (3)
   2. Thale cress (Arabidopsis thaliana), OPR1 [TaxId: 3702] [102040] (2)
      At1G76680
   3. Thale cress (Arabidopsis thaliana), OPR3 [TaxId: 3702] [102041] (5)
4. Glycolate oxidase [51404]
   1. Spinach (Spinacia oleracea) [TaxId: 3562] [51405] (4)
5. Membrane-associated (S)-mandelate dehydrogenase [63898]
   1. Pseudomonas putida [TaxId: 303] [63899] (3)
6. Pentaerythritol tetranirate reductase [63900]
   1. Enterobacter cloacae [TaxId: 550] [63901] (15)
      SQ P71278
7. Morphinone reductase [75053]
   1. Pseudomonas putida [TaxId: 303] [75054] (1)
8. Trimethylamine dehydrogenase, N-terminal domain [51406]
   two other domains are alpha/beta Rossmann-like fold and beta/beta/alpha fold
   1. Methylophilus methylotrophus, w3a1 [TaxId: 17] [51407] (5)
9. 2,4-dienoyl-CoA reductase, N-terminal domain [102042]
   1. Escherichia coli [TaxId: 562] [102043] (1)
10. Flavocytochrome b2, C-terminal domain [51408]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [51409] (16)
       SQ P00175
       N-terminal domain homologous to cytochrome b5
11. Dihydropyrimidine dehydrogenase, domain 4 [51410]
    1. Pig (Sus scrofa) [TaxId: 9823] [51411] (5)
12. Alpha subunit of glutamate synthase, central and FMN domains [69381]
    Central domain (residues 423-780) may be a rudiment form of the FMN domain
    1. Azospirillum brasilense [TaxId: 192] [69382] (7)
    2. Synechocystis sp. [TaxId: 1143] [75055] (5)
13. Isopentenyl-diphosphate delta-isomerase [89454]
    1. Bacillus subtilis [TaxId: 1423] [89455] (2)
    2. Thermus thermophilus [TaxId: 274] [141760] (6)
       SQ Q53W52 23-332
    3. Thermus thermophilus HB8 [TaxId: 300852] [159377] (4)
14. Putative flavin oxidoreducatase TM0096 [102044]
    Dihydrouridine synthase (Dus) homologue; contains extra C-terminal alpha-helical domain
    1. Thermotoga maritima [TaxId: 2336] [102045] (1)
15. PcrB protein homolog YerE [102046]
    provisional classification; it is not known whether this protein binds FMN or not
    1. Bacillus subtilis [TaxId: 1423] [102047] (1)
16. Hydroxyacid oxidase [141761]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [141762] (8)
       SQ Q07523 1-349
17. NADPH dehydrogenase NamA [141763]
    OYE homolog
    1. Bacillus subtilis [TaxId: 1423] [141764] (8)
       SQ P54550 1-337
       probable NADH-dependent flavin oxidoreductase YqjM
18. (S)-3-O-geranylgeranylglyceryl phosphate synthase [141765]
    1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [141766] (4)
       SQ O29844 1-231
       PcrB homolog AF0403

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk