Structural Classification of Proteins

Superfamily: FMN-linked oxidoreductases

: uperfamily

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: TIM beta/alpha-barrel [51350]
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites
Superfamily: FMN-linked oxidoreductases [51395]
uperfamily

Families:

FMN-linked oxidoreductases [51396] (30)
1. Dihydroorotate dehydrogenase [51397]
  1. Lactococcus lactis, isozyme A [TaxId: 1358] [51398] (13)
  2. Lactococcus lactis, isozyme B [TaxId: 1358] [51399] (3)
    PyrD subunit
  3. Escherichia coli [TaxId: 562] [82239] (1)
  4. Human (Homo sapiens) [TaxId: 9606] [51400] (11)
  5. Rat (Rattus norvegicus) [TaxId: 10116] [102039] (2)
  6. Trypanosoma brucei [TaxId: 5691] [141758] (4)
    SQ Q57U83 2-313
  7. Plasmodium falciparum [TaxId: 5833] [141759] (1)
    SQ Q08210 158-566
    homolog, mitochonrial
2. Old yellow enzyme (OYE) [51401]
  1. Lager yeast (Saccharomyces pastorianus) [TaxId: 27292] [51402] (5)
  2. Yeast (Candida albicans) [TaxId: 5476] [51403] (2)
3. 12-oxophytodienoate reductase (OPR, OYE homolog) [63896]
  1. Tomato (Lycopersicon esculentum), OPR1 [TaxId: 4081] [63897] (3)
  2. Thale cress (Arabidopsis thaliana), OPR1 [TaxId: 3702] [102040] (2)
    At1G76680
  3. Thale cress (Arabidopsis thaliana), OPR3 [TaxId: 3702] [102041] (5)
4. Glycolate oxidase [51404]
  1. Spinach (Spinacia oleracea) [TaxId: 3562] [51405] (4)
5. Membrane-associated (S)-mandelate dehydrogenase [63898]
  1. Pseudomonas putida [TaxId: 303] [63899] (3)
6. Pentaerythritol tetranirate reductase [63900]
  1. Enterobacter cloacae [TaxId: 550] [63901] (15)
    SQ P71278
7. Morphinone reductase [75053]
  1. Pseudomonas putida [TaxId: 303] [75054] (1)
8. Trimethylamine dehydrogenase, N-terminal domain [51406]
  two other domains are alpha/beta Rossmann-like fold and beta/beta/alpha fold
  1. Methylophilus methylotrophus, w3a1 [TaxId: 17] [51407] (5)
9. 2,4-dienoyl-CoA reductase, N-terminal domain [102042]
  1. Escherichia coli [TaxId: 562] [102043] (1)
10. Flavocytochrome b2, C-terminal domain [51408]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [51409] (16)
    SQ P00175
    N-terminal domain homologous to cytochrome b5
11. Dihydropyrimidine dehydrogenase, domain 4 [51410]
  1. Pig (Sus scrofa) [TaxId: 9823] [51411] (5)
12. Alpha subunit of glutamate synthase, central and FMN domains [69381]
  Central domain (residues 423-780) may be a rudiment form of the FMN domain
  1. Azospirillum brasilense [TaxId: 192] [69382] (7)
  2. Synechocystis sp. [TaxId: 1143] [75055] (5)
13. Isopentenyl-diphosphate delta-isomerase [89454]
  1. Bacillus subtilis [TaxId: 1423] [89455] (2)
  2. Thermus thermophilus [TaxId: 274] [141760] (6)
    SQ Q53W52 23-332
  3. Thermus thermophilus HB8 [TaxId: 300852] [159377] (4)
14. Putative flavin oxidoreducatase TM0096 [102044]
  Dihydrouridine synthase (Dus) homologue; contains extra C-terminal alpha-helical domain
  1. Thermotoga maritima [TaxId: 2336] [102045] (1)
15. PcrB protein homolog YerE [102046]
  provisional classification; it is not known whether this protein binds FMN or not
  1. Bacillus subtilis [TaxId: 1423] [102047] (1)
16. Hydroxyacid oxidase [141761]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [141762] (8)
    SQ Q07523 1-349
17. NADPH dehydrogenase NamA [141763]
  OYE homolog
  1. Bacillus subtilis [TaxId: 1423] [141764] (8)
    SQ P54550 1-337
    probable NADH-dependent flavin oxidoreductase YqjM
18. (S)-3-O-geranylgeranylglyceryl phosphate synthase [141765]
  1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [141766] (4)
    SQ O29844 1-231
    PcrB homolog AF0403