Structural Classification of Proteins
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Protein: Immunoglobulin heavy chain variable domain, VH from Rat (Rattus norvegicus) [TaxId: 10116]

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: V set domains (antibody variable domain-like) [48727]
  6. Protein: Immunoglobulin heavy chain variable domain, VH [88543]
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species: Rat (Rattus norvegicus) [TaxId: 10116] [88560]

PDB Entry Domains:

  1. 1oaq picpicxref
    part of IgE Fv spe-7
    1. chain h [92707] picpiclink
  2. 1lk3 picpicxrefxrefxrefxref
    part of anti-IL-10 Fab 9D7
    1. region h:1-119 [73952] picpiclink
    2. region i:1-119 [73954] picpiclink
  3. 1oau picpicxref
    part of IgE Fv spe-7
    complexed with dnf, imd, ser
    1. chain h [92717] picpiclink
    2. chain i [92718] picpiclink
    3. chain j [92719] picpiclink
    4. chain k [92720] picpiclink
  4. 1ce1 picpicxrefxrefxref
    part of humanized therapeutic antibody CAMPATH-1H
    1. region h:1-121 [20319] picpiclink
  5. 1oar picpicxref
    part of IgE Fv spe-7
    complexed with azn, cac, cl, dms, edo, na
    1. chain h [92709] picpiclink
    2. chain i [92710] picpiclink
    3. chain j [92711] picpiclink
    4. chain k [92712] picpiclink
  6. 1bfo picpicxrefxrefxref
    part of therapeutic monoclonal antibody CAMPATH-1G
    1. region b:1-121 [20311] picpiclink
    2. region d:1-121 [20313] picpiclink
    3. region f:1-121 [20315] picpiclink
    4. region h:1-121 [20317] picpiclink
  7. 1oax picpicxref
    part of IgE Fv spe-7
    complexed with anq
    1. chain h [92725] picpiclink
    2. chain j [92727] picpiclink
  8. 2bjm picpicxref
    automatically matched to d1oarh_
    complexed with anf
    1. region h:1-120 [128624] picpiclink
  9. 1oay picpicxref
    part of IgE Fv spe-7
    complexed with fur
    1. chain h [92733] picpiclink
    2. chain j [92735] picpiclink
  10. 1c5d picpicxrefxrefxref
    part of antibody against the main immunogenic region of the human muscle acetylcholine receptor
    1. region h:1-117 [20413] picpiclink
    2. region b:1-117 [20415] picpiclink
  11. 2arj picpicxrefxrefxrefxrefxrefxrefxrefxref
    1. region b:1-113 [144831] picpiclink
  12. 2arj picpicxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to 2ARJ B:1-113
    1. region h:1-113 [144833] picpiclink
  13. 1bey picpicxrefxrefxref
    part of antibody to CAMPATH-1H humanized Fab
    1. region h:1-121 [20321] picpiclink
  14. 1fn4 picpicxrefxrefxref
    part of Fab 198 against acetylcholine receptor
    1. region b:1-106 [59886] picpiclink
    2. region d:1-106 [59890] picpiclink
  15. 1f3r picpicxref
    part of scFv MAB198 against the main immunogenic region of the human muscle acetylcholine receptor; order: VH-linker-VL
    mutant
    1. region b:1-123 [20416] picpiclink
  16. 1ocw picpicxref
    part of IgE Fv spe-7
    1. chain h [92779] picpiclink
  17. 1oaz picpicxrefxref
    part of IgE Fv spe-7
    1. chain h [92743] picpiclink
    2. chain j [92744] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk