Structural Classification of Proteins
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Protein: Immunoglobulin light chain kappa variable domain, VL-kappa from Rat (Rattus norvegicus) [TaxId: 10116]

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: V set domains (antibody variable domain-like) [48727]
  6. Protein: Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species: Rat (Rattus norvegicus) [TaxId: 10116] [88532]

PDB Entry Domains:

  1. 1lk3 picpicxrefxrefxrefxref
    part of anti-IL-10 Fab 9D7
    1. region l:1-106 [73956] picpiclink
    2. region m:1-106 [73958] picpiclink
  2. 1ce1 picpicxrefxrefxref
    part of humanized therapeutic antibody CAMPATH-1H
    1. region l:1-107 [20318] picpiclink
  3. 1bfo picpicxrefxrefxref
    part of therapeutic monoclonal antibody CAMPATH-1G
    1. region a:1-107 [20310] picpiclink
    2. region c:1-107 [20312] picpiclink
    3. region e:1-107 [20314] picpiclink
    4. region g:1-107 [20316] picpiclink
  4. 1c5d picpicxrefxrefxref
    part of antibody against the main immunogenic region of the human muscle acetylcholine receptor
    1. region l:1-106 [20412] picpiclink
    2. region a:1-106 [20414] picpiclink
  5. 2arj picpicxrefxrefxrefxrefxrefxrefxrefxref
    1. region a:1-107 [144829] picpiclink
  6. 2arj picpicxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to 2ARJ A:1-107
    1. region l:1-107 [144835] picpiclink
  7. 1za3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1c5da1
    1. region a:1-106 [124787] picpiclink
  8. 1za3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1c5da1
    1. region l:1-106 [124793] picpiclink
  9. 1bey picpicxrefxrefxref
    part of antibody to CAMPATH-1H humanized Fab
    1. region l:1-107 [20320] picpiclink
  10. 1fn4 picpicxrefxrefxref
    part of Fab 198 against acetylcholine receptor
    1. region a:1-107 [59884] picpiclink
    2. region c:1-107 [59888] picpiclink
  11. 1f3r picpicxref
    part of scFv MAB198 against the main immunogenic region of the human muscle acetylcholine receptor; order: VH-linker-VL
    mutant
    1. region b:139-257 [20417] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk