Structural Classification of Proteins
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Protein: Immunoglobulin heavy chain variable domain, VH from Mouse (Mus musculus), cluster 2.2 [TaxId: 10090]

SQ P01811 # HV41_MOUSE (P01811) Ig heavy chain V region UPC10

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: V set domains (antibody variable domain-like) [48727]
  6. Protein: Immunoglobulin heavy chain variable domain, VH [88543]
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species: Mouse (Mus musculus), cluster 2.2 [TaxId: 10090] [88550]
    SQ P01811 # HV41_MOUSE (P01811) Ig heavy chain V region UPC10

PDB Entry Domains:

  1. 1mqk picpicxref
    part of Fv against Paracoccus denitrificans cytochrome c oxidase
    1. chain h [85053] picpiclink
  2. 1i8k picpicxref
    part of dsFv MR1; complex with a EGFR-VIII peptide
    mutant
    1. chain b [71131] picpiclink
  3. 2hff picpicxrefxref
    automatically matched to d1mf2h1
    1. region b:1-113 [136379] picpiclink
  4. 2hff picpicxrefxref
    automatically matched to d1mf2h1
    1. region h:1-113 [136381] picpiclink
  5. 1qkz picpicxrefxrefxrefxref
    part of Fab MN14C11.6
    1. region h:1-113 [20137] picpiclink
  6. 1dsf picpicxref
    part of anticancer Fv B1; disulfide-stabilized
    mutant
    1. chain h [20247] picpiclink
  7. 1h0d picpicxrefxrefxrefxref
    part of anti-angiogenin FAB; conflict: annotated in PDB as human
    complexed with gol, pca, so4
    1. region b:1-113 [83427] picpiclink
  8. 1hil picpicxrefxrefxref
    part of Fab 17/9
    1. region b:1-112 [19787] picpiclink
    2. region d:1-112 [19789] picpiclink
  9. 1cfv picpicxref
    part of Fv 4155
    complexed with e3g, zn
    1. chain h [20161] picpiclink
  10. 1bfv picpicxref
    part of Fv 4155
    complexed with stg, zn
    1. chain h [20163] picpiclink
  11. 1bm3 picpicxrefxrefxref
    part of anti-integrin Fab OPG2
    1. region h:1-125 [20067] picpiclink
  12. 2fbj picpicxrefxrefxref
    part of Fab J539
    complexed with fuc, nag, zn
    1. region h:1-118 [19851] picpiclink
  13. 2hrp picpicxrefxrefxref
    part of Fab F11.2.32 against HIV-1 protease
    1. region h:1-113 [20171] picpiclink
    2. region n:1-113 [20173] picpiclink
  14. 1i8i picpicxref
    part of dsFv MR1; complex with a EGFR-VIII peptide
    mutant
    1. chain b [71129] picpiclink
  15. 1opg picpicxrefxrefxref
    part of anti-integrin Fab OPG2
    1. region h:1-125 [20069] picpiclink
  16. 1f4x picpicxrefxrefxref
    part of anti-carbohydrate Fab S-20-4
    complexed with mgs
    1. region h:1-117 [20451] picpiclink
  17. 1ejo picpicxrefxrefxref
    part of anti-FMDV Fab 4C4
    1. region h:2501-2619 [20429] picpiclink
  18. 2bfv picpicxref
    part of Fv 4155
    complexed with stg
    1. chain h [20165] picpiclink
  19. 1f4w picpicxrefxrefxref
    part of anti-carbohydrate Fab S-20-4
    1. region h:1-117 [20453] picpiclink
  20. 3ehb picpicxrefxrefxref
    automatically matched to d1mqkh_
    complexed with ca, cu, hea, lda, lmt, mg, per; mutant
    1. region c:1-119 [158152] picpiclink
  21. 1ikf picpicxrefxrefxref
    part of an anti-cyclosporin A Fab
    complexed with aba
    1. region h:1-126 [20033] picpiclink
  22. 1ucb picpicxrefxrefxref
    part of humanized Fab CBR96
    complexed with so4
    1. region h:1-113 [20101] picpiclink
  23. 2j4w picpicxrefxrefxrefxref
    mutant
    1. region h:1-112 [145646] picpiclink
  24. 2hfg picpicxref
    automatically matched to d1mf2h1
    mutant
    1. region h:1-113 [136383] picpiclink
  25. 1ind picpicxrefxrefxref
    part of Fab Cha255
    complexed with eot, in
    1. region h:1-114 [19839] picpiclink
  26. 2h1p picpicxrefxrefxref
    part of polysaccharide binding antibody 2H1
    1. region h:301-420 [20191] picpiclink
  27. 1mf2 picpicxrefxrefxref
    part of Fab F11.2.32 against HIV-1 protease
    1. region h:1-113 [20175] picpiclink
    2. region n:1-113 [20177] picpiclink
  28. 1bz7 picpicxrefxrefxref
    part of humanized Fab R24 from murine ascites
    1. region b:1-122 [20403] picpiclink
  29. 1ar1 picpicxrefxrefxrefxref
    part of Fv against Paracoccus denitrificans cytochrome c oxidase
    complexed with ca, cu, hea, lda, mg
    1. chain c [20207] picpiclink
  30. 1bln picpicxrefxrefxref
    part of anti-P-glycoprotein Fab MRK-16
    1. region b:1-113 [20331] picpiclink
    2. region d:1-113 [20333] picpiclink
  31. 1frg picpicxrefxrefxref
    part of Fab 26/9
    complexed with nh2
    1. region h:218-336 [19925] picpiclink
  32. 1cly picpicxrefxrefxref
    part of humanized Fab CBR96
    complexed with fuc, gal, nag, non
    1. region h:1-113 [20103] picpiclink
  33. 1clz picpicxrefxrefxref
    part of Fab MBR96
    complexed with fuc, gal, nag, non
    1. region h:1-113 [20105] picpiclink
  34. 1fh5 picpicxrefxrefxref
    part of Fab MAK33; conflict: annotated in PDB as human protein
    1. region h:4-120 [20465] picpiclink
  35. 1ots picpicxrefxrefxrefxref
    part of anti-CLC chloride channel Fab
    complexed with cl
    1. region c:2-121 [87417] picpiclink
    2. region e:2-121 [87421] picpiclink
  36. 1ifh picpicxrefxrefxref
    part of Fab 17/9
    1. region h:1-112 [19791] picpiclink
  37. 1igc picpicxrefxrefxrefxref
    part of Fab MoPC21
    1. region h:1-119 [20047] picpiclink
  38. 1ine picpicxrefxrefxref
    part of Fab Cha255
    complexed with eot, fe
    1. region h:1-114 [19841] picpiclink
  39. 1igf picpicxrefxrefxref
    part of Fab B13I2
    complexed with nag
    1. region h:1-113 [19813] picpiclink
    2. region j:1-113 [19815] picpiclink
  40. 1igt picpicxrefxrefxrefxrefxref
    part of intact IgG2a antibody Mab231
    complexed with fuc, gal, man, nag
    1. region b:1-114 [19765] picpiclink
    2. region d:1-114 [19767] picpiclink
  41. 1h3p picpicxrefxrefxref
    part of anti-hepatitis B Fab (against PRES1 region)
    1. region h:1-113 [76648] picpiclink
  42. 1him picpicxrefxrefxref
    part of Fab 17/9; chain identifiers are mixed up
    complexed with nh2
    1. region l:1-112 [19792] picpiclink
    2. region m:1-112 [19794] picpiclink
  43. 2igf picpicxrefxrefxref
    part of Fab B13I2
    complexed with nag
    1. region h:1-113 [19817] picpiclink
  44. 1qle picpicxrefxrefxrefxrefxrefxref
    part of Fv against Paracoccus denitrificans cytochrome c oxidase
    1. chain h [20209] picpiclink
  45. 1f4y picpicxrefxrefxref
    part of anti-carbohydrate Fab S-20-4
    complexed with mgu
    1. region h:1-117 [20455] picpiclink
  46. 1hin picpicxrefxrefxref
    part of Fab 17/9
    1. region h:1-112 [19797] picpiclink
  47. 1kno picpicxrefxrefxref
    part of Fab CNJ206
    complexed with pnp, zn
    1. region b:1-119 [20009] picpiclink
    2. region d:1-119 [20011] picpiclink
    3. region f:1-119 [20013] picpiclink
  48. 2j5l picpicxrefxrefxrefxref
    automatically matched to 2J4W H:1-112
    mutant
    1. region c:1-112 [145663] picpiclink
  49. 1ott picpicxrefxrefxrefxref
    part of anti-CLC chloride channel Fab
    complexed with cl; mutant
    1. region c:2-121 [87427] picpiclink
    2. region e:2-121 [87431] picpiclink
  50. 1qfw picpicxrefxrefxrefxrefxref
    part of anti-[gonadotropin beta subunit] Fv
    complexed with nag
    1. chain i [20437] picpiclink
  51. 1otu picpicxrefxrefxrefxref
    part of anti-CLC chloride channel Fab
    complexed with cl; mutant
    1. region c:2-121 [87437] picpiclink
    2. region e:2-121 [87441] picpiclink
  52. 1r24 picpicxrefxrefxref
    part of humanized Fab R24 from murine ascites
    1. region b:1-122 [20405] picpiclink
    2. region d:1-122 [20407] picpiclink
  53. 1uz8 picpicxrefxrefxref
    MQ P01811 P22436 # ! natural chimera
    complexed with fuc, gal, mag
    1. region b:1-113 [108168] picpiclink
    2. region h:1-113 [108170] picpiclink
  54. 1uz6 picpicxrefxrefxref
    MQ P01811 P22436 # ! natural chimera
    complexed with so4
    1. region f:1-113 [108152] picpiclink
    2. region h:1-113 [108154] picpiclink
    3. region p:1-113 [108160] picpiclink
    4. region w:1-113 [108164] picpiclink
  55. 2gfb picpicxrefxrefxref
    part of Fab CNJ206; H-chains in this entry seem to be mistraced in VH region
    1. region b:1-119 [19993] picpiclink
    2. region d:1-119 [19995] picpiclink
    3. region f:1-119 [19997] picpiclink
    4. region h:1-119 [19999] picpiclink
    5. region j:1-119 [20001] picpiclink
    6. region l:1-119 [20003] picpiclink
    7. region n:1-119 [20005] picpiclink
    8. region p:1-119 [20007] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk