Structural Classification of Proteins
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Family: Hef domain-like

helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain (scop_fa 81795, that contains a single NMR structure of a monomeric truncated domain, 1kft)

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: SAM domain-like [47768]
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
  4. Superfamily: RuvA domain 2-like [47781]
    duplication: contains two helix-hairpin-helix (HhH) motifs
    link to SUPERFAMILY database - Superfamily
  5. Family: Hef domain-like [140629]
    helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain (scop_fa 81795, that contains a single NMR structure of a monomeric truncated domain, 1kft)

Protein Domains:

  1. DNA excision repair protein ERCC-1 [140630]
    1. Human (Homo sapiens) [TaxId: 9606] [140631] (2) picpic
      SQ P07992 219-296! SQ P07992 220-297
  2. ATP-dependent RNA helicase PF2015 [140632]
    1. Pyrococcus furiosus [TaxId: 2261] [140633] (2) picpic
      SQ Q8TZH8 694-761
  3. DNA repair endonuclease XPF [140634]
    1. Aeropyrum pernix [TaxId: 56636] [140635] (6) picpic
      SQ Q9YC15 160-229
    2. Human (Homo sapiens) [TaxId: 9606] [140636] (4) picpic
      SQ Q92889 823-905! SQ Q92889 837-898
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk