Structural Classification of Proteins

Superfamily: EF-hand

: Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
uperfamily

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: EF Hand-like [47472]
core: 4 helices; array of 2 hairpins, opened
Superfamily: EF-hand [47473]
Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
uperfamily

Calbindin D9K [47474] (2)
made of two EF-hands only
S100 proteins [47478] (17)
dimer: subunits are made of two EF-hands
Polcalcin [89048] (3)
calcium-binding pollen allergen; two EF-hands per subunit
Osteonectin [47489] (1)
5 helices; two EF-hands plus one of additional helices in the N-terminal part
Parvalbumin [47492] (9)
6-helices; array of 3 hairpins, closed
made with two-helical hairpin and two EF-hands
Calmodulin-like [47502] (49)
Duplication: made with two pairs of EF-hands
Eps15 homology domain (EH domain) [47543] (4)
Cbp40 (plasmodial specific CaII-binding protein LAV1-2) [81758] (1)
4 EF-hands assembled in a compact structure like the Penta-EF-hand proteins; contains additional N-terminal all-alpha subdomain
Penta-EF-hand proteins [63550] (11)
EF-hand modules in multidomain proteins [47547] (8)
p25-alpha [140538] (2)
Pfam 05517; comprises two degenerate EF-hands and extra C-terminal helix, packed agains the bundle end