Structural Classification of Proteins
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Family: Calmodulin-like

Duplication: made with two pairs of EF-hands

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: EF Hand-like [47472]
    core: 4 helices; array of 2 hairpins, opened
  4. Superfamily: EF-hand [47473]
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
    link to SUPERFAMILY database - Superfamily
  5. Family: Calmodulin-like [47502]
    Duplication: made with two pairs of EF-hands

Protein Domains:

  1. Troponin C [47503]
    1. Chicken (Gallus gallus) [TaxId: 9031] [47504] (28) picpic
      SQ P09860
    2. Turkey (Meleagris gallopavo) [TaxId: 9103] [47505] (2) picpic
    3. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [47506] (4) picpic
    4. Chicken (Gallus gallus), cardiac isoform [TaxId: 9031] [47507] (1) picpic
    5. Human (Homo sapiens), cardiac isoform [TaxId: 9606] [47508] (21) picpic
    6. Rainbow trout (Oncorhynchus mykiss) [TaxId: 8022] [109819] (2) picpic
      SQ Q7ZZB9 1-89
  2. Sarcoplasmic calcium-binding protein [47509]
    1. Sandworm (Nereis diversicolor) [TaxId: 126592] [47510] (2) picpic
      SQ P04571
    2. Amphioxus (Branchiostoma lanceolatum) [TaxId: 7740] [47511] (1) picpic
  3. Calcium vector protein [47514]
    1. Amphioxus (Branchiostoma lanceolatum) [TaxId: 7740] [47515] (4) picpic
  4. Calcium-regulated photoprotein [47512]
    structurally most similar to sarcoplasmic calcium-binding protein
    1. Jellyfish (Aequorea aequorea), aequorin [TaxId: 168712] [47513] (9) picpic
    2. Hydrozoa (Obelia longissima), obelin [TaxId: 32570] [63541] (7) picpic
      SQ Q27709
    3. Hydrozoa (Obelia geniculata), obelin [TaxId: 185004] [63542] (1) picpic
    4. Jellyfish (Aequorea victoria), aequorin 1 [TaxId: 6100] [116901] (1) picpic
      SQ P07164 16-196
  5. Calerythrin [101179]
    structurally most similar to sarcoplasmic calcium-binding protein
    1. Saccharopolyspora erythraea [TaxId: 1836] [101180] (1) picpic
  6. EHCABP [69021]
    1. Entamoeba (Entamoeba histolytica) [TaxId: 5759] [69022] (2) picpic
  7. Calmodulin [47516]
    1. Human (Homo sapiens) [TaxId: 9606] [47517] (60) picpic
      SQ P02593
    2. Cow (Bos taurus) [TaxId: 9913] [47518] (56) picpic
      SQ P62157
    3. Rat (Rattus rattus) [TaxId: 10117] [47519] (5) picpic
      SQ P62161
    4. Chicken (Gallus gallus) [TaxId: 9031] [47520] (2) picpic
      mutant with a two residue deletion in the central helix
    5. African frog (Xenopus laevis) [TaxId: 8355] [47521] (13) picpic
    6. Drosophila melanogaster [TaxId: 7227] [47522] (6) picpic
    7. Nematode (Caenorhabditis elegans) [TaxId: 6239] [89051] (1) picpic
    8. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89052] (3) picpic
    9. Ciliate (Paramecium tetraurelia) [TaxId: 5888] [47523] (4) picpic
      SQ Q42478
    10. Potato (Solanum tuberosum) [TaxId: 4113] [109820] (1) picpic
    11. Rattus norvegicus [TaxId: 10116] [158477] (2) picpic
  8. Calmodulin-related protein NB-1 (CLP) [74721]
    1. Human (Homo sapiens) [TaxId: 9606] [74722] (1) picpic
  9. Caltractin (centrin 2) [89053]
    1. Human (Homo sapiens) [TaxId: 9606] [89054] (5) picpic
    2. Green algae (Chlamydomonas reinhardtii) [TaxId: 3055] [89055] (1) picpic
  10. Cdc4p [63543]
    1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [63544] (1) picpic
  11. Myosin Light Chain Mlc1p [81756]
    light chain of class V myosin
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [81757] (3) picpic
  12. Myosin Essential Chain [47524]
    1. Bay scallop (Aequipecten irradians) [TaxId: 31199] [47525] (13) picpic
      SQ P13543
    2. Chicken (Gallus gallus) [TaxId: 9031] [47526] (5) picpic
    3. Human (Homo sapiens) [TaxId: 9606] [101181] (3) picpic
  13. Myosin Regulatory Chain [47527]
    1. Bay scallop (Aequipecten irradians) [TaxId: 31199] [47528] (13) picpic
      SQ P07291
    2. Chicken (Gallus gallus) [TaxId: 9031] [47529] (1) picpic
  14. Calcineurin regulatory subunit (B-chain) [47530]
    1. Cow (Bos taurus) [TaxId: 9913] [47531] (3) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [47532] (3) picpic
  15. Calcineurin B-like protein 2 [101182]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [101183] (2) picpic
  16. Recoverin [47533]
    Calcium-myristoyl switch; only one EF-hand is functional
    1. Cow (Bos taurus) [TaxId: 9913] [47534] (11) picpic
  17. Kchip1, Kv4 potassium channel-interacting protein [101184]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [101185] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [116902] (1) picpic
      SQ Q9NZI2
  18. Frequenin (neuronal calcium sensor 1) [47535]
    1. Human (Homo sapiens) [TaxId: 9606] [63545] (1) picpic
    2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [47536] (2) picpic
  19. Guanylate cyclase activating protein 2, GCAP-2 [47537]
    1. Cow (Bos taurus) [TaxId: 9913] [47538] (1) picpic
  20. Neurocalcin [47539]
    1. Cow (Bos taurus) [TaxId: 9913] [47540] (1) picpic
  21. Calcium- and integrin-binding protein, CIB [47541]
    1. Human (Homo sapiens) [TaxId: 9606] [47542] (5) picpic
      SQ Q99828
  22. Calcium-dependent protein kinase sk5 CLD [109821]
    1. Soybean (Glycine max) [TaxId: 3847] [109822] (2) picpic
      SQ P28583 328-508
  23. Calmodulin-related protein T21P5.17 [109823]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [109824] (1) picpic
      SQ Q9SRP5 2-67
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk