Structural Classification of Proteins
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Protein: Interleukin-2 (IL-2) from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: 4-helical cytokines [47265]
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. Superfamily: 4-helical cytokines [47266]
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
    link to SUPERFAMILY database - Superfamily
  5. Family: Short-chain cytokines [47286]
  6. Protein: Interleukin-2 (IL-2) [47301]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [47302]

PDB Entry Domains:

  1. 1m48 picpic
    complexed with frg
    1. chain a [74443] picpiclink
    2. chain b [74444] picpiclink
  2. 1m47 picpic
    complexed with sul
    1. chain a [74442] picpiclink
  3. 1m49 picpic
    complexed with cmm
    1. chain a [74445] picpiclink
    2. chain b [74446] picpiclink
  4. 1nbp picpic
    complexed with mhc, sul; mutant
    1. chain a [80392] picpiclink
  5. 1m4b picpic
    complexed with nmp; mutant
    1. chain a [74448] picpiclink
  6. 2b5i picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1m48b_
    complexed with nag; mutant
    1. region a:6-133 [127895] picpiclink
  7. 1m4a picpic
    complexed with gol, mpe; mutant
    1. chain a [74447] picpiclink
  8. 3ink picpic
    mutant
    1. chain c [16881] picpiclink
    2. chain d [16882] picpiclink
  9. 1m4c picpic
    1. chain a [74449] picpiclink
    2. chain b [74450] picpiclink
  10. 1pw6 picpic
    complexed with a small molecule inhibitor
    complexed with frb, so4
    1. chain a [95200] picpiclink
    2. chain b [95201] picpiclink
  11. 2erj picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d3inkc_
    complexed with bma, fuc, nag; mutant
    1. region d:6-133 [132294] picpiclink
  12. 2erj picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d3inkc_
    complexed with bma, fuc, nag; mutant
    1. region h:6-133 [132301] picpiclink
  13. 1z92 picpicxrefxref
    automatically matched to d1m48b_
    1. region a:6-133 [124737] picpiclink
  14. 1py2 picpic
    complexed with a small molecule inhibitor
    complexed with frh, zn
    1. chain a [95319] picpiclink
    2. chain b [95320] picpiclink
    3. chain c [95321] picpiclink
    4. chain d [95322] picpiclink
  15. 1irl picpic
    mutant
    1. chain a [16883] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk