Structural Classification of Proteins
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Protein: Granulocyte-macrophage colony-stimulating factor (GM-CSF) from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: 4-helical cytokines [47265]
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. Superfamily: 4-helical cytokines [47266]
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
    link to SUPERFAMILY database - Superfamily
  5. Family: Short-chain cytokines [47286]
  6. Protein: Granulocyte-macrophage colony-stimulating factor (GM-CSF) [47289]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [47290]

PDB Entry Domains:

  1. 2gmf picpic
    1. chain a [16849] picpiclink
    2. chain b [16850] picpiclink
  2. 1csg picpic
    1. chain a [16851] picpiclink
    2. chain b [16852] picpiclink
  3. 3cxe picpic
    automatically matched to d2gmfa_
    complexed with bma, nag; mutant
    1. region b:14-118 [157108] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk