Structural Classification of Proteins
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Protein: Estrogen receptor alpha from Human (Homo sapiens) [TaxId: 9606]

SQ P03372 307-551

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Nuclear receptor ligand-binding domain [48507]
    multihelical; 3 layers or orthogonally packed helices
  4. Superfamily: Nuclear receptor ligand-binding domain [48508]
    link to SUPERFAMILY database - Superfamily
  5. Family: Nuclear receptor ligand-binding domain [48509]
  6. Protein: Estrogen receptor alpha [48519]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [48520]
    SQ P03372 307-551

PDB Entry Domains:

  1. 1xpc picpic
    complexed with ait
    1. chain a [115738] picpiclink
  2. 1xp6 picpic
    complexed with aiu
    1. chain a [115734] picpiclink
  3. 1l2i picpic
    complexed with ccs, cl, etc
    1. chain a [73503] picpiclink
    2. chain b [73504] picpiclink
  4. 2iog picpic
    automatically matched to d1qkua_
    complexed with iog
    1. region a:309-550 [147744] picpiclink
  5. 1xp1 picpic
    complexed with aih
    1. chain a [115721] picpiclink
  6. 2ayr picpic
    automatically matched to d1qkta_
    complexed with l4g; mutant
    1. region a:307-548 [127569] picpiclink
  7. 2pog picpic
    automatically matched to d1qkta_
    complexed with wst; mutant
    1. region a:306-550 [149721] picpiclink
  8. 1xp9 picpic
    complexed with aij
    1. chain a [115737] picpiclink
  9. 2ouz picpic
    automatically matched to d1qkua_
    complexed with c3d
    1. region a:306-550 [139378] picpiclink
  10. 2r6y picpic
    automatically matched to d1qkta_
    complexed with llc; mutant
    1. region a:306-549 [151623] picpiclink
  11. 2r6y picpic
    automatically matched to d1qkta_
    complexed with llc; mutant
    1. region b:306-545 [151624] picpiclink
  12. 2r6w picpic
    automatically matched to d1qkta_
    complexed with llb; mutant
    1. region a:306-549 [151621] picpiclink
  13. 2r6w picpic
    automatically matched to d1qkta_
    complexed with llb; mutant
    1. region b:306-546 [151622] picpiclink
  14. 3ert picpic
    complex with 4-hydroxytamoxifen
    complexed with oht
    1. chain a [19292] picpiclink
  15. 2q70 picpic
    automatically matched to d1qkta_
    complexed with dc8; mutant
    1. region a:306-549 [150072] picpiclink
  16. 3erd picpic
    complex with diethylstilbestrol and a peptide
    complexed with cbm, cl, des
    1. chain a [19293] picpiclink
    2. chain b [19294] picpiclink
  17. 3dt3 picpic
    automatically matched to d1qkua_
    complexed with 369
    1. region a:306-550 [157848] picpiclink
  18. 3dt3 picpic
    automatically matched to d1qkua_
    complexed with 369
    1. region b:306-548 [157849] picpiclink
  19. 1qkt picpic
    complex with estradiol
    complexed with est; mutant
    1. chain a [19295] picpiclink
  20. 1sj0 picpic
    complexed with e4d
    1. chain a [98893] picpiclink
  21. 1xqc picpic
    automatically matched to d1qkta_
    complexed with aej; mutant
    1. region a:307-548 [122233] picpiclink
  22. 1xqc picpic
    automatically matched to d1qkta_
    complexed with aej; mutant
    1. region b:307-548 [122234] picpiclink
  23. 1xqc picpic
    automatically matched to d1qkta_
    complexed with aej; mutant
    1. region c:307-548 [122235] picpiclink
  24. 1xqc picpic
    automatically matched to d1qkta_
    complexed with aej; mutant
    1. region d:307-548 [122236] picpiclink
  25. 1uom picpic
    complexed with pti; mutant
    1. chain a [88497] picpiclink
  26. 1gwq picpic
    complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
    complexed with ztw
    1. chain a [76366] picpiclink
    2. chain b [76367] picpiclink
  27. 1gwr picpic
    complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
    complexed with est
    1. chain a [76368] picpiclink
    2. chain b [76369] picpiclink
  28. 1pcg picpic
    complexed with est; mutant
    1. chain a [94432] picpiclink
    2. chain b [94433] picpiclink
  29. 1a52 picpic
    complexed with au, est
    1. chain a [19296] picpiclink
    2. chain b [19297] picpiclink
  30. 1r5k picpic
    complexed with gw5
    1. chain a [111706] picpiclink
    2. chain b [111707] picpiclink
    3. chain c [111708] picpiclink
  31. 1err picpic
    complexed with cbm, ral
    1. chain a [19298] picpiclink
    2. chain b [19299] picpiclink
  32. 1ere picpic
    complexed with est
    1. chain a [19300] picpiclink
    2. chain b [19301] picpiclink
    3. chain c [19302] picpiclink
    4. chain d [19303] picpiclink
    5. chain e [19304] picpiclink
    6. chain f [19305] picpiclink
  33. 1qku picpic
    complex with estradiol
    complexed with est
    1. chain a [19306] picpiclink
    2. chain b [19307] picpiclink
    3. chain c [19308] picpiclink
  34. 2iok picpic
    automatically matched to d1qkua_
    complexed with iok
    1. region a:306-544 [147747] picpiclink
  35. 2iok picpic
    automatically matched to d1qkua_
    complexed with iok
    1. region b:1306-1544 [147748] picpiclink
  36. 1g50 picpic
    complexed with est
    1. chain a [65149] picpiclink
    2. chain b [65150] picpiclink
    3. chain c [65151] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk