Structural Classification of Proteins
home mail help root up expand collapse

Superfamily: Nuclear receptor ligand-binding domain

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Nuclear receptor ligand-binding domain [48507]
    multihelical; 3 layers or orthogonally packed helices
  4. Superfamily: Nuclear receptor ligand-binding domain [48508]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Nuclear receptor ligand-binding domain [48509] (44)
    1. Retinoid-X receptor alpha (RXR-alpha) [48510]
      1. Human (Homo sapiens) [TaxId: 9606] [48511] (21) picpic
        SQ P19793 227-458
      2. Mouse (Mus musculus) [TaxId: 10090] [48512] (2) picpic
        SQ P28700 232-463
    2. Retinoid-X receptor beta (RXR-beta) [74792]
      1. Human (Homo sapiens) [TaxId: 9606] [74793] (2) picpic
        SQ P28702 298-528
    3. Retinoic acid receptor alpha (RAR-alpha) [48513]
      1. Human (Homo sapiens) [TaxId: 9606] [48514] (1) picpic
    4. Retinoic acid receptor gamma (RAR-gamma) [48515]
      1. Human (Homo sapiens) [TaxId: 9606] [48516] (9) picpic
    5. Glucocorticoid receptor [89140]
      1. Human (Homo sapiens) [TaxId: 9606] [89141] (4) picpic
    6. Orphan nuclear receptor NURR1 [89142]
      1. Human (Homo sapiens) [TaxId: 9606] [89143] (1) picpic
    7. Nuclear hormone receptor HR38 [89144]
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [89145] (1) picpic
    8. Progesterone receptor [48517]
      1. Human (Homo sapiens) [TaxId: 9606] [48518] (8) picpic
        SQ P06401 679-932
    9. Estrogen receptor alpha [48519]
      1. Human (Homo sapiens) [TaxId: 9606] [48520] (36) picpic
        SQ P03372 307-551
    10. Estrogen receptor beta [48521]
      1. Human (Homo sapiens) [TaxId: 9606] [48522] (36) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [48523] (4) picpic
    11. Androgen receptor [63621]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [63622] (7) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [63623] (36) picpic
        SQ P10275 671-919
      3. Chimpanzee (Pan troglodytes) [TaxId: 9598] [109986] (8) picpic
        SQ O97775 661-910 # 100% sequence identity to human sequence (SQ P10275 669-918)
    12. Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109]
      1. Human (Homo sapiens) [TaxId: 9606] [69110] (5) picpic
    13. Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524]
      1. Human (Homo sapiens) [TaxId: 9606] [48525] (72) picpic
        SQ P37231 232-505
    14. Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526]
      1. Human (Homo sapiens) [TaxId: 9606] [48527] (18) picpic
    15. Pregnane x receptor, PXR [63624]
      1. Human (Homo sapiens) [TaxId: 9606] [63625] (6) picpic
    16. Vitamin D nuclear receptor [48528]
      1. Human (Homo sapiens) [TaxId: 9606] [48529] (13) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [101432] (12) picpic
    17. Thyroid hormone receptor beta (TR-beta) [48530]
      1. Human (Homo sapiens) [TaxId: 9606] [48531] (11) picpic
        SQ P10828 202-460
    18. Thyroid hormone receptor alpha1 (TR-alpha1) [48532]
      1. Human (Homo sapiens) [TaxId: 9606] [88962] (1) picpic
    19. Ultraspiracle protein, usp [48534]
      the ortholog of RXRs in insects
      1. Drosophila melanogaster [TaxId: 7227] [48535] (1) picpic
      2. Heliothis virescens [TaxId: 7102] [63626] (4) picpic
    20. Orphan nuclear receptor ROR-alpha [81914]
      1. Human (Homo sapiens) [TaxId: 9606] [81915] (2) picpic
    21. Orphan nuclear receptor ROR-beta [74794]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [74795] (3) picpic
    22. Orphan nuclear receptor ERR3 [81916]
      1. Human (Homo sapiens) [TaxId: 9606] [81917] (26) picpic
        SQ O75454 233-458
    23. Hepatocyte nuclear factor 4-gamma [81918]
      1. Human (Homo sapiens) [TaxId: 9606] [81919] (1) picpic
    24. Hepatocyte nuclear factor 4-alpha [109605]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [89146] (1) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [109987] (1) picpic
        SQ P41235 139-369
    25. Orphan nuclear receptor NR5a2 (LRH-1) [89147]
      1. Mouse (Mus musculus) [TaxId: 10090] [89148] (1) picpic
    26. Oxysterols receptor LXR-beta [89149]
      1. Human (Homo sapiens) [TaxId: 9606] [89150] (6) picpic
        SQ P55055 219-461
    27. Bile acid receptor FXR [101433]
      1. Human (Homo sapiens) [TaxId: 9606] [101434] (5) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [101435] (2) picpic
    28. Ecdysone receptor [101436]
      1. Noctuid moth (Heliothis virescens) [TaxId: 7102] [101437] (3) picpic
    29. Oxysterols receptor LXR-alpha [109988]
      1. Human (Homo sapiens) [TaxId: 9606] [109989] (1) picpic
        SQ Q13133 207-445
      2. Mouse (Mus musculus) [TaxId: 10090] [158810] (4) picpic
        SQ Q9Z0Y9 203-443
    30. Steroid hormone receptor ERR1 [109990]
      1. Human (Homo sapiens) [TaxId: 9606] [109991] (3) picpic
        SQ P11474 289-516
    31. Retinoic acid receptor beta (RAR-beta) [117011]
      1. Mouse (Mus musculus) [TaxId: 10090] [117012] (1) picpic
        SQ P22605 209-453
      2. Human (Homo sapiens) [TaxId: 9606] [117013] (1) picpic
        SQ P10826 182-416
    32. Orphan nuclear receptor NR1I3 (CAR) [117014]
      1. Mouse (Mus musculus) [TaxId: 10090] [117015] (2) picpic
        SQ O35627 109-358
      2. Human (Homo sapiens) [TaxId: 9606] [117016] (2) picpic
        SQ Q14994 103-352
    33. Orphan nuclear receptor NR4A1 [158811]
      1. Human (Homo sapiens) [TaxId: 9606] [158812] (4) picpic
        SQ P22736 363-595
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk