Structural Classification of Proteins

Fold: Nuclear receptor ligand-binding domain

: multihelical; 3 layers or orthogonally packed helices

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: Nuclear receptor ligand-binding domain [48507]
multihelical; 3 layers or orthogonally packed helices

Superfamilies:

Nuclear receptor ligand-binding domain [48508] (1)
uperfamily
1. Nuclear receptor ligand-binding domain [48509] (44)
  1. Retinoid-X receptor alpha (RXR-alpha) [48510]
    1. Human (Homo sapiens) [TaxId: 9606] [48511] (21)
      SQ P19793 227-458
      1. 2p1t
        automatically matched to d1lbda_
        complexed with 3tn
        
        region a:229-458 [149165]
      2. 1mvc
        complexed with co-activator peptide
        complexed with bm6
        
        chain a [79499]
      3. 1mzn
        complexed with co-activator peptide
        complexed with bm6
        
        chain a [79704]
        chain c [79705]
        chain e [79706]
        chain g [79707]
      4. 1mv9
        complexed with co-activator peptide
        complexed with hxa
        
        chain a [79498]
      5. 2p1u
        automatically matched to d1lbda_
        complexed with 4tn
        
        region a:229-458 [149166]
      6. 2p1v
        automatically matched to d1lbda_
        complexed with 5tn
        
        region a:229-458 [149167]
      7. 1g5y
        complexed with rea
        
        chain a [60294]
        chain b [60295]
        chain c [60296]
        chain d [60297]
      8. 1fm9
        complexed with 570, rea
        
        chain a [19274]
      9. 1rdt
        complexed with co-activator peptide
        complexed with 570, l79
        
        chain a [111787]
      10. 1fby
        complex with 9-cis retinoic acid
        complexed with rea
        
        chain a [19275]
        chain b [19276]
      11. 1k74
        heterodimer with PPAR-gamma complexed with co-activator peptides
        complexed with 544, rea
        
        chain a [68251]
      12. 1fm6
        complexed with brl, rea
        
        chain a [19277]
        chain u [19278]
      13. 1g1u
        
        chain a [60204]
        chain b [60205]
        chain c [60206]
        chain d [60207]
      14. 1xvp
        complexed with cid, f15
        
        chain a [116090]
        chain c [116092]
      15. 1xv9
        complexed with ci2, f15
        
        chain a [116080]
        chain c [116082]
      16. 2acl
        automatically matched to d1lbd__
        complexed with l05, rea
        
        region a:225-457 [126559]
      17. 2acl
        automatically matched to d1lbd__
        complexed with l05, rea
        
        region c:225-457 [126560]
      18. 2acl
        automatically matched to d1lbd__
        complexed with l05, rea
        
        region e:225-457 [126561]
      19. 2acl
        automatically matched to d1lbd__
        complexed with l05, rea
        
        region g:225-457 [126562]
      20. 1lbd
        
        chain a [19279]
      21. 1xdk
        complexed with co-activator peptide
        complexed with rea
        
        chain a [115164]
        chain e [115166]
    2. Mouse (Mus musculus) [TaxId: 10090] [48512] (2)
      SQ P28700 232-463
      1. 1dkf
        complexed with bms, oli; mutant
        
        chain a [19280]
      2. 1xls
        complexed with rea, tcd; mutant
        
        chain a [115447]
        chain b [115448]
        chain c [115449]
        chain d [115450]
  2. Retinoid-X receptor beta (RXR-beta) [74792]
    1. Human (Homo sapiens) [TaxId: 9606] [74793] (2)
      SQ P28702 298-528
      1. 1h9u
        complexed with cl, lg2, ni
        
        chain a [70923]
        chain b [70924]
        chain c [70925]
        chain d [70926]
      2. 1uhl
        complexed with 444, mei
        
        chain a [107849]
  3. Retinoic acid receptor alpha (RAR-alpha) [48513]
    1. Human (Homo sapiens) [TaxId: 9606] [48514] (1)
      1. 1dkf
        complexed with bms, oli; mutant
        
        chain b [19281]
  4. Retinoic acid receptor gamma (RAR-gamma) [48515]
    1. Human (Homo sapiens) [TaxId: 9606] [48516] (9)
      1. 1fcy
        complexed with 564, lmu
        
        chain a [19282]
      2. 1fcz
        complexed with 156, lmu
        
        chain a [19283]
      3. 1fd0
        complexed with 254, lmu
        
        chain a [76164]
      4. 1fcx
        complexed with 184, lmu
        
        chain a [19284]
      5. 1exa
        complexed with 394, lmu
        
        chain a [19285]
      6. 1exx
        complexed with 395, lmu
        
        chain a [19286]
      7. 2lbd
        complexed with rea
        
        chain a [19287]
      8. 3lbd
        complexed with rea
        
        chain a [19288]
      9. 4lbd
        complexed with 961
        
        chain a [19289]
  5. Glucocorticoid receptor [89140]
    1. Human (Homo sapiens) [TaxId: 9606] [89141] (4)
      1. 1nhz
        complexed with 486, hez; mutant
        
        chain a [85727]
      2. 3bqd
        automatically matched to d1m2za_
        complexed with day; mutant
        
        region a:525-777 [155498]
      3. 1m2z
        complexed with coactivator peptide, chains B and E
        complexed with bog, dex; mutant
        
        chain a [84768]
        chain d [84769]
      4. 1p93
        complexed with coactivator peptide, chains E, F, G and H
        complexed with dex; mutant
        
        chain a [87986]
        chain b [87987]
        chain c [87988]
        chain d [87989]
  6. Orphan nuclear receptor NURR1 [89142]
    1. Human (Homo sapiens) [TaxId: 9606] [89143] (1)
      1. 1ovl
        complexed with br, iod, k, mse
        
        chain a [87455]
        chain b [87456]
        chain c [87457]
        chain d [87458]
        chain e [87459]
        chain f [87460]
  7. Nuclear hormone receptor HR38 [89144]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [89145] (1)
      1. 1pdu
        
        chain a [88034]
        chain b [88035]
  8. Progesterone receptor [48517]
    1. Human (Homo sapiens) [TaxId: 9606] [48518] (8)
      SQ P06401 679-932
      1. 1sqn
        complexed with ndr
        
        chain a [105944]
        chain b [105945]
      2. 1sr7
        complexed with gol, mof, so4
        
        chain a [105957]
        chain b [105958]
      3. 1a28
        complexed with str
        
        chain a [19290]
        chain b [19291]
      4. 1zuc
        automatically matched to d1a28a_
        complexed with so4, t98
        
        region a:682-932 [125666]
      5. 1zuc
        automatically matched to d1a28a_
        complexed with so4, t98
        
        region b:682-932 [125667]
      6. 2ovh
        automatically matched to d1a28a_
        complexed with as0
        
        region a:682-932 [139380]
      7. 2ovm
        automatically matched to d1a28a_
        complexed with as0
        
        region a:682-932 [139381]
      8. 1e3k
        complexed with r18
        
        chain a [59193]
        chain b [59194]
  9. Estrogen receptor alpha [48519]
    1. Human (Homo sapiens) [TaxId: 9606] [48520] (36)
      SQ P03372 307-551
      1. 1xpc
        complexed with ait
        
        chain a [115738]
      2. 1xp6
        complexed with aiu
        
        chain a [115734]
      3. 1l2i
        complexed with ccs, cl, etc
        
        chain a [73503]
        chain b [73504]
      4. 2iog
        automatically matched to d1qkua_
        complexed with iog
        
        region a:309-550 [147744]
      5. 1xp1
        complexed with aih
        
        chain a [115721]
      6. 2ayr
        automatically matched to d1qkta_
        complexed with l4g; mutant
        
        region a:307-548 [127569]
      7. 2pog
        automatically matched to d1qkta_
        complexed with wst; mutant
        
        region a:306-550 [149721]
      8. 1xp9
        complexed with aij
        
        chain a [115737]
      9. 2ouz
        automatically matched to d1qkua_
        complexed with c3d
        
        region a:306-550 [139378]
      10. 2r6y
        automatically matched to d1qkta_
        complexed with llc; mutant
        
        region a:306-549 [151623]
      11. 2r6y
        automatically matched to d1qkta_
        complexed with llc; mutant
        
        region b:306-545 [151624]
      12. 2r6w
        automatically matched to d1qkta_
        complexed with llb; mutant
        
        region a:306-549 [151621]
      13. 2r6w
        automatically matched to d1qkta_
        complexed with llb; mutant
        
        region b:306-546 [151622]
      14. 3ert
        complex with 4-hydroxytamoxifen
        complexed with oht
        
        chain a [19292]
      15. 2q70
        automatically matched to d1qkta_
        complexed with dc8; mutant
        
        region a:306-549 [150072]
      16. 3erd
        complex with diethylstilbestrol and a peptide
        complexed with cbm, cl, des
        
        chain a [19293]
        chain b [19294]
      17. 3dt3
        automatically matched to d1qkua_
        complexed with 369
        
        region a:306-550 [157848]
      18. 3dt3
        automatically matched to d1qkua_
        complexed with 369
        
        region b:306-548 [157849]
      19. 1qkt
        complex with estradiol
        complexed with est; mutant
        
        chain a [19295]
      20. 1sj0
        complexed with e4d
        
        chain a [98893]
      21. 1xqc
        automatically matched to d1qkta_
        complexed with aej; mutant
        
        region a:307-548 [122233]
      22. 1xqc
        automatically matched to d1qkta_
        complexed with aej; mutant
        
        region b:307-548 [122234]
      23. 1xqc
        automatically matched to d1qkta_
        complexed with aej; mutant
        
        region c:307-548 [122235]
      24. 1xqc
        automatically matched to d1qkta_
        complexed with aej; mutant
        
        region d:307-548 [122236]
      25. 1uom
        complexed with pti; mutant
        
        chain a [88497]
      26. 1gwq
        complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
        complexed with ztw
        
        chain a [76366]
        chain b [76367]
      27. 1gwr
        complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
        complexed with est
        
        chain a [76368]
        chain b [76369]
      28. 1pcg
        complexed with est; mutant
        
        chain a [94432]
        chain b [94433]
      29. 1a52
        complexed with au, est
        
        chain a [19296]
        chain b [19297]
      30. 1r5k
        complexed with gw5
        
        chain a [111706]
        chain b [111707]
        chain c [111708]
      31. 1err
        complexed with cbm, ral
        
        chain a [19298]
        chain b [19299]
      32. 1ere
        complexed with est
        
        chain a [19300]
        chain b [19301]
        chain c [19302]
        chain d [19303]
        chain e [19304]
        chain f [19305]
      33. 1qku
        complex with estradiol
        complexed with est
        
        chain a [19306]
        chain b [19307]
        chain c [19308]
      34. 2iok
        automatically matched to d1qkua_
        complexed with iok
        
        region a:306-544 [147747]
      35. 2iok
        automatically matched to d1qkua_
        complexed with iok
        
        region b:1306-1544 [147748]
      36. 1g50
        complexed with est
        
        chain a [65149]
        chain b [65150]
        chain c [65151]
  10. Estrogen receptor beta [48521]
    1. Human (Homo sapiens) [TaxId: 9606] [48522] (36)
      1. 1qkm
        complex with partial agonist genistein
        complexed with gen
        
        chain a [19309]
      2. 2nv7
        automatically matched to d1l2jb_
        complexed with 555
        
        region a:263-497 [148458]
      3. 2nv7
        automatically matched to d1l2jb_
        complexed with 555
        
        region b:263-497 [148459]
      4. 1yye
        automatically matched to d1l2jb_
        complexed with 196
        
        region a:263-497 [124213]
      5. 1yye
        automatically matched to d1l2jb_
        complexed with 196
        
        region b:263-496 [124214]
      6. 1x76
        automatically matched to d1l2jb_
        complexed with 697
        
        region a:263-497 [121777]
      7. 1x76
        automatically matched to d1l2jb_
        complexed with 697
        
        region b:263-497 [121778]
      8. 2jj3
        automatically matched to d1l2jb_
        complexed with jj3
        
        region a:261-497 [148127]
      9. 2jj3
        automatically matched to d1l2jb_
        complexed with jj3
        
        region b:261-497 [148128]
      10. 1u3r
        automatically matched to d1l2jb_
        complexed with 338
        
        region a:263-497 [119522]
      11. 1u3r
        automatically matched to d1l2jb_
        complexed with 338
        
        region b:263-497 [119523]
      12. 1x7j
        automatically matched to d1l2jb_
        complexed with gen
        
        region a:263-497 [121788]
      13. 1x7j
        automatically matched to d1l2jb_
        complexed with gen
        
        region b:263-497 [121789]
      14. 2z4b
        automatically matched to d1l2jb_
        complexed with dc8
        
        region a:261-497 [154048]
      15. 2z4b
        automatically matched to d1l2jb_
        complexed with dc8
        
        region b:261-497 [154049]
      16. 1x78
        automatically matched to d1l2jb_
        complexed with 244
        
        region a:263-497 [121779]
      17. 1x78
        automatically matched to d1l2jb_
        complexed with 244
        
        region b:263-497 [121780]
      18. 1x7b
        automatically matched to d1l2jb_
        complexed with 041
        
        region a:263-497 [121784]
      19. 1x7b
        automatically matched to d1l2jb_
        complexed with 041
        
        region b:263-497 [121785]
      20. 1u9e
        automatically matched to d1l2jb_
        complexed with 397
        
        region a:263-497 [119635]
      21. 1u9e
        automatically matched to d1l2jb_
        complexed with 397
        
        region b:263-497 [119636]
      22. 1u3s
        automatically matched to d1l2jb_
        complexed with 797
        
        region a:263-497 [119524]
      23. 1u3s
        automatically matched to d1l2jb_
        complexed with 797
        
        region b:263-497 [119525]
      24. 2i0g
        automatically matched to d1l2jb_
        complexed with i0g
        
        region a:261-497 [136950]
      25. 2i0g
        automatically matched to d1l2jb_
        complexed with i0g
        
        region b:261-497 [136951]
      26. 1u3q
        automatically matched to d1l2jb_
        complexed with 272
        
        region a:263-497 [119518]
      27. 1u3q
        automatically matched to d1l2jb_
        complexed with 272
        
        region b:263-497 [119519]
      28. 1u3q
        automatically matched to d1l2jb_
        complexed with 272
        
        region c:263-497 [119520]
      29. 1u3q
        automatically matched to d1l2jb_
        complexed with 272
        
        region d:263-497 [119521]
      30. 2qtu
        automatically matched to d1l2jb_
        complexed with 3as
        
        region a:261-497 [151355]
      31. 2qtu
        automatically matched to d1l2jb_
        complexed with 3as
        
        region b:261-497 [151356]
      32. 2giu
        automatically matched to d1l2jb_
        complexed with fbr
        
        region a:260-497 [135252]
      33. 1yy4
        automatically matched to d1l2jb_
        complexed with 4na
        
        region a:263-497 [124205]
      34. 1yy4
        automatically matched to d1l2jb_
        complexed with 4na
        
        region b:263-497 [124206]
      35. 1l2j
        complexed with etc
        
        chain a [73505]
        chain b [73506]
      36. 1nde
        complex with selective triazine modulator
        complexed with mon
        
        chain a [80415]
    2. Rat (Rattus norvegicus) [TaxId: 10116] [48523] (4)
      1. 2j7y
        automatically matched to d1qkna_
        complexed with bct, e3o, edo, so4
        
        region a:217-452 [138130]
      2. 2j7x
        automatically matched to d1qkna_
        complexed with bct, edo, est, so4
        
        region a:217-452 [138129]
      3. 1qkn
        complex with antagonist raloxifene
        complexed with act, ral
        
        chain a [19310]
      4. 1hj1
        complexed with aoe, ni, pmb
        
        chain a [65843]
  11. Androgen receptor [63621]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [63622] (7)
      1. 2ax6
        automatically matched to d1i38a_
        complexed with hft; mutant
        
        region a:672-917 [127479]
      2. 2ax7
        automatically matched to d1i38a_
        complexed with fhm; mutant
        
        region a:672-917 [127480]
      3. 2oz7
        automatically matched to d1i38a_
        complexed with ca4; mutant
        
        region a:672-918 [139441]
      4. 1gs4
        complexed with po4, zk5; mutant
        
        chain a [76328]
      5. 1i37
        complexed with dht
        
        chain a [61583]
      6. 1xnn
        automatically matched to d1i38a_
        complexed with hyq; mutant
        
        region a:672-918 [122197]
      7. 1i38
        complexed with dht; mutant
        
        chain a [61584]
    2. Human (Homo sapiens) [TaxId: 9606] [63623] (36)
      SQ P10275 671-919
      1. 2pnu
        automatically matched to d1e3ga_
        complexed with dtt, enm, mes, so4
        
        region a:670-918 [149706]
      2. 2am9
        automatically matched to d1e3ga_
        complexed with dtt, gol, so4, tes
        
        region a:670-918 [126999]
      3. 3b66
        automatically matched to d1e3ga_
        complexed with b66
        
        region a:671-917 [154877]
      4. 2q7i
        automatically matched to d1e3ga_
        complexed with gol, so4, tes
        
        region a:671-918 [150086]
      5. 2ax9
        automatically matched to d1e3ga_
        complexed with bhm
        
        region a:672-917 [127481]
      6. 1t65
        automatically matched to d1e3ga_
        complexed with dht
        
        region a:669-918 [119159]
      7. 2amb
        automatically matched to d1e3ga_
        complexed with 17h, dtt, epe, gol, so4
        
        region a:671-918 [127001]
      8. 2q7j
        automatically matched to d1e3ga_
        complexed with gol, so4, tes
        
        region a:671-918 [150087]
      9. 2axa
        automatically matched to d1e3ga_
        complexed with fhm
        
        region a:672-917 [127482]
      10. 1xow
        complexed with r18
        
        chain a [115717]
      11. 3b5r
        automatically matched to d1e3ga_
        complexed with b5r
        
        region a:671-917 [154851]
      12. 2ao6
        automatically matched to d1e3ga_
        complexed with r18
        
        region a:671-918 [127068]
      13. 2pit
        automatically matched to d1e3ga_
        complexed with 4hy, dht, so4
        
        region a:670-918 [149517]
      14. 2ama
        automatically matched to d1e3ga_
        complexed with dht, so4
        
        region a:671-918 [127000]
      15. 3b65
        automatically matched to d1e3ga_
        complexed with 3b6
        
        region a:671-917 [154876]
      16. 2pip
        automatically matched to d1e3ga_
        complexed with dht, ico, k10, so4
        
        region l:670-918 [149514]
      17. 3b67
        automatically matched to d1e3ga_
        complexed with b67
        
        region a:671-917 [154878]
      18. 3b68
        automatically matched to d1e3ga_
        complexed with b68
        
        region a:671-917 [154879]
      19. 1t63
        automatically matched to d1e3ga_
        complexed with dht
        
        region a:669-918a [119158]
      20. 2piv
        automatically matched to d1e3ga_
        complexed with dht, so4, t3
        
        region a:670-918 [149519]
      21. 1xq3
        complexed with r18
        
        chain a [115820]
      22. 2hvc
        automatically matched to d1e3ga_
        complexed with lgd
        
        region a:670-918 [147418]
      23. 2pio
        automatically matched to d1e3ga_
        complexed with 2mi, dht, so4
        
        region a:671-918 [149513]
      24. 2piu
        automatically matched to d1e3ga_
        complexed with 4hy, dht
        
        region a:671-918 [149518]
      25. 2ihq
        automatically matched to d1e3ga_
        complexed with lg7
        
        region a:671-918 [137423]
      26. 1t5z
        automatically matched to d1e3ga_
        complexed with dht
        
        region a:669-918 [119157]
      27. 2pir
        automatically matched to d1e3ga_
        complexed with dht, nk, so4
        
        region a:670-918 [149516]
      28. 2piq
        automatically matched to d1e3ga_
        complexed with dht, rb1, so4
        
        region a:670-918 [149515]
      29. 2pkl
        automatically matched to d1e3ga_
        complexed with 4hy, dht
        
        region a:670-918 [149604]
      30. 1e3g
        complexed with r18
        
        chain a [59192]
      31. 2pix
        automatically matched to d1e3ga_
        complexed with dht, flf
        
        region a:671-918 [149521]
      32. 2z4j
        automatically matched to d1e3ga_
        complexed with dht
        
        region a:671-918 [154050]
      33. 2piw
        automatically matched to d1e3ga_
        complexed with dht, t3
        
        region a:671-918 [149520]
      34. 2qpy
        automatically matched to d1e3ga_
        complexed with 4hy, dht
        
        region a:671-918 [151217]
      35. 1xj7
        automatically matched to d1e3ga_
        complexed with dht
        
        region a:669-918 [122031]
      36. 2nw4
        automatically matched to d1e3ga_
        complexed with 8nh
        
        region a:671-918 [138709]
    3. Chimpanzee (Pan troglodytes) [TaxId: 9598] [109986] (8)
      SQ O97775 661-910 # 100% sequence identity to human sequence (SQ P10275 669-918)
      1. 1t7r
        complexed with dht
        
        chain a [106635]
      2. 1t7f
        complexed with dht
        
        chain a [106625]
      3. 1t7t
        complexed with dht
        
        chain a [106638]
      4. 1t7m
        complexed with dht, edo, so4
        
        chain a [106626]
      5. 1t79
        complexed with dht
        
        chain a [106619]
      6. 1t74
        complexed with dht, edo, so4
        
        chain a [106613]
      7. 1t76
        complexed with dht, edo, na, so4
        
        chain a [106618]
      8. 1t73
        complexed with dht, so4
        
        chain a [106612]
  12. Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109]
    1. Human (Homo sapiens) [TaxId: 9606] [69110] (5)
      1. 2p54
        automatically matched to d1i7ga_
        complexed with 735
        
        region a:202-468 [139497]
      2. 1i7g
        complex with the agonist AZ 242
        complexed with az2, cpq, na
        
        chain a [71121]
      3. 2rew
        automatically matched to d1i7ga_
        complexed with cpq, rew
        
        region a:199-467 [151991]
      4. 1k7l
        complexed with a co-activator peptide
        complexed with 544, yt3
        
        chain a [68268]
        chain c [68269]
        chain e [68270]
        chain g [68271]
      5. 1kkq
        complexed with an antagonist and a SMRT corepressor peptide
        complexed with 471
        
        chain a [68679]
        chain b [68680]
        chain c [68681]
        chain d [68682]
  13. Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524]
    1. Human (Homo sapiens) [TaxId: 9606] [48525] (72)
      SQ P37231 232-505
      1. 2fvj
        automatically matched to d1wm0x_
        complexed with gol, ro0
        
        region a:207-477 [134203]
      2. 1zgy
        automatically matched to d1wm0x_
        complexed with brl
        
        region a:206-477 [125064]
      3. 2q5s
        automatically matched to d1wm0x_
        complexed with nza
        
        region a:208-477 [150053]
      4. 2q5s
        automatically matched to d1wm0x_
        complexed with nza
        
        region b:207-476 [150054]
      5. 2vsr
        automatically matched to d1wm0x_
        complexed with 9ho
        
        region a:207-475 [153529]
      6. 2vsr
        automatically matched to d1wm0x_
        complexed with 9ho
        
        region b:207-474 [153530]
      7. 2q59
        automatically matched to d1wm0x_
        complexed with 240
        
        region a:207-475 [150043]
      8. 2q59
        automatically matched to d1wm0x_
        complexed with 240
        
        region b:207-475 [150044]
      9. 2hfp
        automatically matched to d1wm0x_
        complexed with nsi
        
        region a:206-477 [136388]
      10. 2prg
        complexed with brl
        
        chain a [19311]
        chain b [19312]
      11. 2gtk
        automatically matched to d1wm0x_
        complexed with 208
        
        region a:207-477 [135654]
      12. 2q61
        automatically matched to d1wm0x_
        complexed with sf1
        
        region a:209-477 [150055]
      13. 2q61
        automatically matched to d1wm0x_
        complexed with sf1
        
        region b:207-476 [150056]
      14. 2hwq
        automatically matched to d1wm0x_
        complexed with dry
        
        region a:207-477 [147427]
      15. 2f4b
        automatically matched to d1wm0x_
        complexed with eha
        
        region a:207-477 [132918]
      16. 2f4b
        automatically matched to d1wm0x_
        complexed with eha
        
        region b:207-477 [132919]
      17. 1fm9
        complexed with 570, rea
        
        chain d [19313]
      18. 1rdt
        complexed with co-activator peptide
        complexed with 570, l79
        
        chain d [111788]
      19. 2q5p
        automatically matched to d1wm0x_
        complexed with 241
        
        region a:207-476 [150051]
      20. 2q5p
        automatically matched to d1wm0x_
        complexed with 241
        
        region b:207-475 [150052]
      21. 2vv1
        automatically matched to d1wm0x_
        complexed with 4hd
        
        region a:206-475 [153607]
      22. 2i4j
        automatically matched to d1wm0x_
        complexed with drj
        
        region a:207-476 [137049]
      23. 2i4j
        automatically matched to d1wm0x_
        complexed with drj
        
        region b:207-476 [137050]
      24. 1prg
        
        chain a [19314]
        chain b [19315]
      25. 2p4y
        automatically matched to d1wm0x_
        complexed with c03, trs
        
        region a:205-477 [149221]
      26. 2p4y
        automatically matched to d1wm0x_
        complexed with c03, trs
        
        region b:209-477 [149222]
      27. 2q8s
        automatically matched to d1wm0x_
        complexed with l92
        
        region a:207-474 [150131]
      28. 2q8s
        automatically matched to d1wm0x_
        complexed with l92
        
        region b:207-475 [150132]
      29. 2vv4
        automatically matched to d1wm0x_
        complexed with 6ob, 6oc
        
        region a:205-475 [153612]
      30. 2ath
        automatically matched to d1wm0x_
        complexed with 3ea
        
        region a:207-477 [127291]
      31. 2ath
        automatically matched to d1wm0x_
        complexed with 3ea
        
        region b:207-477 [127292]
      32. 2i4p
        automatically matched to d1wm0x_
        complexed with drh
        
        region a:207-476 [137051]
      33. 2i4p
        automatically matched to d1wm0x_
        complexed with drh
        
        region b:207-476 [137052]
      34. 2i4z
        automatically matched to d1wm0x_
        complexed with drh
        
        region a:207-476 [137053]
      35. 2i4z
        automatically matched to d1wm0x_
        complexed with drh
        
        region b:207-476 [137054]
      36. 2pob
        automatically matched to d1wm0x_
        complexed with gol, gw4
        
        region a:207-475 [149717]
      37. 2pob
        automatically matched to d1wm0x_
        complexed with gol, gw4
        
        region b:206-474 [149718]
      38. 1k74
        heterodimer with RXR-alpha complexed with co-activator peptides
        complexed with 544, rea
        
        chain d [68252]
      39. 2q6s
        automatically matched to d1wm0x_
        complexed with plb
        
        region a:207-474 [150070]
      40. 2q6s
        automatically matched to d1wm0x_
        complexed with plb
        
        region b:207-475 [150071]
      41. 2vst
        automatically matched to d1wm0x_
        complexed with 243
        
        region a:205-475 [153531]
      42. 2vst
        automatically matched to d1wm0x_
        complexed with 243
        
        region b:207-474 [153532]
      43. 1fm6
        complexed with brl, rea
        
        chain d [19316]
        chain x [19317]
      44. 1i7i
        complex with the agonist AZ 242
        complexed with az2
        
        chain a [71125]
        chain b [71126]
      45. 1knu
        complexed with ypa
        
        chain a [77457]
        chain b [77458]
      46. 3cs8
        automatically matched to d1wm0x_
        complexed with brl, so4
        
        region a:206-476 [156958]
      47. 2hwr
        automatically matched to d1wm0x_
        complexed with drd
        
        region a:207-477 [147428]
      48. 2vv0
        automatically matched to d1wm0x_
        complexed with f22
        
        region a:205-475 [153605]
      49. 2vv0
        automatically matched to d1wm0x_
        complexed with f22
        
        region b:208-476 [153606]
      50. 2g0h
        automatically matched to d1wm0x_
        complexed with sp3
        
        region a:207-477 [134493]
      51. 2g0h
        automatically matched to d1wm0x_
        complexed with sp3
        
        region b:207-477 [134494]
      52. 1zeo
        automatically matched to d1wm0x_
        complexed with c01
        
        region a:207-477 [124992]
      53. 1zeo
        automatically matched to d1wm0x_
        complexed with c01
        
        region b:207-475 [124993]
      54. 2g0g
        automatically matched to d1wm0x_
        complexed with sp0
        
        region a:207-477 [134491]
      55. 2g0g
        automatically matched to d1wm0x_
        complexed with sp0
        
        region b:207-477 [134492]
      56. 3prg
        
        chain a [19318]
      57. 3cwd
        automatically matched to d1wm0x_
        complexed with lna, lnb
        
        region a:208-477 [157049]
      58. 3cwd
        automatically matched to d1wm0x_
        complexed with lna, lnb
        
        region b:208-476 [157050]
      59. 2vv2
        automatically matched to d1wm0x_
        complexed with 5he
        
        region a:207-474 [153608]
      60. 2vv2
        automatically matched to d1wm0x_
        complexed with 5he
        
        region b:207-474 [153609]
      61. 2om9
        automatically matched to d1wm0x_
        complexed with aja
        
        region a:207-476 [139142]
      62. 2om9
        automatically matched to d1wm0x_
        complexed with aja
        
        region b:207-476 [139143]
      63. 2om9
        automatically matched to d1wm0x_
        complexed with aja
        
        region c:207-476 [139144]
      64. 2om9
        automatically matched to d1wm0x_
        complexed with aja
        
        region d:207-476 [139145]
      65. 2q6r
        automatically matched to d1wm0x_
        complexed with sf2
        
        region a:207-476 [150068]
      66. 2q6r
        automatically matched to d1wm0x_
        complexed with sf2
        
        region b:207-477 [150069]
      67. 2vv3
        automatically matched to d1wm0x_
        complexed with 4r8
        
        region a:207-475 [153610]
      68. 2vv3
        automatically matched to d1wm0x_
        complexed with 4r8
        
        region b:207-474 [153611]
      69. 1nyx
        complexed with drf
        
        chain a [86431]
        chain b [86432]
      70. 1wm0
        complexed with plb
        
        chain x [109404]
      71. 4prg
        complexed with 072
        
        chain a [19319]
        chain b [19320]
        chain c [19321]
        chain d [19322]
      72. 2qmv
        automatically matched to d1wm0x_
        
        region a:207-476 [150898]
  14. Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526]
    1. Human (Homo sapiens) [TaxId: 9606] [48527] (18)
      1. 2b50
        automatically matched to d2gwxb_
        complexed with b7g, ca, vca
        
        region a:211-476 [127872]
      2. 2b50
        automatically matched to d2gwxb_
        complexed with b7g, ca, vca
        
        region b:211-475 [127873]
      3. 2awh
        automatically matched to d2gwxb_
        complexed with b7g, vca
        
        region a:211-476 [127433]
      4. 2awh
        automatically matched to d2gwxb_
        complexed with b7g, vca
        
        region b:211-476 [127434]
      5. 2baw
        automatically matched to d2gwxb_
        complexed with b7g, vca
        
        region a:211-475 [128248]
      6. 2baw
        automatically matched to d2gwxb_
        complexed with b7g, vca
        
        region b:211-476 [128249]
      7. 2gwx
        
        chain a [19323]
        chain b [19324]
      8. 1y0s
        automatically matched to d1gwxa_
        complexed with 331, b7g, iod
        
        region a:207-475 [122512]
      9. 1y0s
        automatically matched to d1gwxa_
        complexed with 331, b7g, iod
        
        region b:209-475 [122513]
      10. 3d5f
        automatically matched to d2gwxb_
        complexed with l41; mutant
        
        region a:211-476 [157397]
      11. 3d5f
        automatically matched to d2gwxb_
        complexed with l41; mutant
        
        region b:211-476 [157398]
      12. 3gwx
        complexed with epa
        
        chain a [19325]
        chain b [19326]
      13. 3dy6
        automatically matched to d1gwxa_
        complexed with dy6, iod
        
        region a:210-474 [157935]
      14. 3dy6
        automatically matched to d1gwxa_
        complexed with dy6, iod
        
        region b:210-474 [157936]
      15. 2j14
        automatically matched to d1gwxa_
        complexed with gni
        
        region a:174-440 [137935]
      16. 2j14
        automatically matched to d1gwxa_
        complexed with gni
        
        region b:175-439 [137936]
      17. 2q5g
        automatically matched to d1gwxa_
        complexed with 1fa
        
        region a:210-474 [150050]
      18. 1gwx
        complexed with 433
        
        chain a [19327]
        chain b [19328]
  15. Pregnane x receptor, PXR [63624]
    1. Human (Homo sapiens) [TaxId: 9606] [63625] (6)
      1. 1nrl
        complexed with an src-1 coactivator peptide and sr12813
        complexed with srl
        
        chain a [92091]
        chain b [92092]
      2. 1m13
        complexed with hyf
        
        chain a [84746]
      3. 1ilg
        
        chain a [62544]
      4. 1skx
        automatically matched to d1m13a_
        complexed with rfp
        
        region a:143-431 [118970]
      5. 1ilh
        complexed with srl
        
        chain a [62545]
      6. 2qnv
        automatically matched to d1m13a_
        complexed with cdz
        
        region a:142-434 [150955]
  16. Vitamin D nuclear receptor [48528]
    1. Human (Homo sapiens) [TaxId: 9606] [48529] (13)
      1. 1ie9
        complexed with vdx
        
        chain a [62318]
      2. 1ie8
        complexed with kh1
        
        chain a [62317]
      3. 2hb7
        automatically matched to d1ie9a_
        complexed with o1c
        
        region a:119-423 [136307]
      4. 1db1
        
        chain a [19329]
      5. 1txi
        automatically matched to d1ie9a_
        complexed with tx5
        
        region a:120-423 [119387]
      6. 2ham
        automatically matched to d1ie9a_
        complexed with c33
        
        region a:119-423 [136290]
      7. 2har
        automatically matched to d1ie9a_
        complexed with occ
        
        region a:119-423 [136293]
      8. 2has
        automatically matched to d1ie9a_
        complexed with c3o
        
        region a:119-423 [136294]
      9. 2hb8
        automatically matched to d1ie9a_
        complexed with mvd
        
        region a:119-423 [136308]
      10. 3cs6
        automatically matched to d1ie9a_
        complexed with 0co
        
        region a:119-423 [156955]
      11. 1s19
        complexed with mc9
        
        chain a [98339]
      12. 3cs4
        automatically matched to d1ie9a_
        complexed with cov
        
        region a:119-423 [156954]
      13. 1s0z
        complexed with eb1
        
        chain a [98326]
    2. Rat (Rattus norvegicus) [TaxId: 10116] [101432] (12)
      1. 2zmi
        automatically matched to d1rkha_
        complexed with edo, fmt, tt2; mutant
        
        region a:123-419 [154691]
      2. 2o4j
        automatically matched to d1rkha_
        complexed with vd4; mutant
        
        region a:123-421 [138908]
      3. 1rkg
        complexed with vd1; mutant
        
        chain a [97611]
      4. 2o4r
        automatically matched to d1rkha_
        complexed with vd5; mutant
        
        region a:123-421 [138913]
      5. 1rjk
        complexed with vdz; mutant
        
        chain a [97571]
      6. 2zl9
        automatically matched to d1rkha_
        complexed with vda
        
        region a:123-419 [154626]
      7. 2zla
        automatically matched to d1rkha_
        complexed with vdb
        
        region a:123-419 [154627]
      8. 2zlc
        automatically matched to d1rkha_
        complexed with vdx
        
        region a:123-419 [154629]
      9. 2zmh
        automatically matched to d1rkha_
        complexed with nya; mutant
        
        region a:123-419 [154690]
      10. 1rkh
        complexed with vd2; mutant
        
        chain a [97612]
      11. 1rk3
        complexed with vdx; mutant
        
        chain a [97591]
      12. 2zmj
        automatically matched to d1rkha_
        complexed with mi4; mutant
        
        region a:123-419 [154692]
  17. Thyroid hormone receptor beta (TR-beta) [48530]
    1. Human (Homo sapiens) [TaxId: 9606] [48531] (11)
      SQ P10828 202-460
      1. 1n46
        complexed with pfa
        
        chain a [85315]
        chain b [85316]
      2. 2h6w
        automatically matched to d1y0xx_
        complexed with cas, t3
        
        region x:202-460 [136204]
      3. 1nq0
        complexed with 4hy, ars; mutant
        
        chain a [86005]
      4. 1nax
        complexed with ih5
        
        chain a [85501]
      5. 1xzx
        complexed with cac, t3
        
        chain x [116274]
      6. 1nq2
        complexed with 4hy, ars, na; mutant
        
        chain a [86007]
      7. 1q4x
        complexed with g24
        
        chain a [95833]
      8. 1nq1
        complexed with 4hy, ars; mutant
        
        chain a [86006]
      9. 1y0x
        complexed with cac, t44
        
        chain x [116316]
      10. 1nuo
        complexed with 4hy; mutant
        
        chain a [86198]
      11. 1bsx
        complexed with t3
        
        chain a [19330]
        chain b [19331]
  18. Thyroid hormone receptor alpha1 (TR-alpha1) [48532]
    1. Human (Homo sapiens) [TaxId: 9606] [88962] (1)
      1. 1nav
        complexed with ih5, so4
        
        chain a [85500]
  19. Ultraspiracle protein, usp [48534]
    the ortholog of RXRs in insects
    1. Drosophila melanogaster [TaxId: 7227] [48535] (1)
      1. 1hg4
        complexed with lpp
        
        chain a [19333]
        chain b [19334]
        chain c [19335]
        chain d [19336]
        chain e [19337]
        chain f [19338]
    2. Heliothis virescens [TaxId: 7102] [63626] (4)
      1. 1g2n
        complexed with eph
        
        chain a [60227]
      2. 2r40
        automatically matched to d1g2na_
        complexed with 20e, eph, flc, gol, so4
        
        region a:206-455 [151571]
      3. 1r1k
        complexed with eph, p1a
        
        chain a [96818]
      4. 1r20
        complexed with eph, hwg
        
        chain a [96844]
  20. Orphan nuclear receptor ROR-alpha [81914]
    1. Human (Homo sapiens) [TaxId: 9606] [81915] (2)
      1. 1n83
        complexed with clr
        
        chain a [80276]
      2. 1s0x
        complexed with c3s
        
        chain a [98313]
  21. Orphan nuclear receptor ROR-beta [74794]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [74795] (3)
      1. 1nq7
        complexed with a co-activator peptide, chain B
        complexed with arl
        
        chain a [92047]
      2. 1k4w
        complexed with ste
        
        chain a [72068]
      3. 1n4h
        complexed with a co-activator peptide, chain B
        complexed with rea
        
        chain a [91618]
  22. Orphan nuclear receptor ERR3 [81916]
    1. Human (Homo sapiens) [TaxId: 9606] [81917] (26)
      SQ O75454 233-458
      1. 2e2r
        automatically matched to d1tfca_
        complexed with 2oh, gol
        
        region a:234-456 [146654]
      2. 2gpu
        automatically matched to d1tfca_
        complexed with oht
        
        region a:235-455 [135493]
      3. 2zbs
        automatically matched to d1tfca_
        
        region a:234-456 [154323]
      4. 2gpo
        automatically matched to d1tfca_
        
        region a:235-458 [135484]
      5. 2zas
        automatically matched to d1tfca_
        complexed with 1oh, gol
        
        region a:234-456 [154285]
      6. 2p7g
        automatically matched to d1tfca_
        complexed with 2oh, na
        
        region a:235-456 [149280]
      7. 1s9q
        complexed with chd, oht
        
        chain a [105388]
        chain b [105389]
      8. 2ewp
        automatically matched to d1tfca_
        complexed with txf
        
        region a:235-456 [132488]
      9. 2ewp
        automatically matched to d1tfca_
        complexed with txf
        
        region b:235-456 [132489]
      10. 2ewp
        automatically matched to d1tfca_
        complexed with txf
        
        region c:235-456 [132490]
      11. 2ewp
        automatically matched to d1tfca_
        complexed with txf
        
        region d:235-455 [132491]
      12. 2ewp
        automatically matched to d1tfca_
        complexed with txf
        
        region e:237-455 [132492]
      13. 2p7a
        automatically matched to d1tfca_
        complexed with 43m
        
        region a:234-456 [149279]
      14. 1s9p
        complexed with des
        
        chain a [105384]
        chain b [105385]
        chain c [105386]
        chain d [105387]
      15. 2gp7
        automatically matched to d1tfca_
        complexed with ca
        
        region a:235-458 [135452]
      16. 2gp7
        automatically matched to d1tfca_
        complexed with ca
        
        region b:235-458 [135453]
      17. 2gp7
        automatically matched to d1tfca_
        complexed with ca
        
        region c:235-458 [135454]
      18. 2gp7
        automatically matched to d1tfca_
        complexed with ca
        
        region d:235-458 [135455]
      19. 1tfc
        
        chain a [106850]
        chain b [106851]
      20. 2gpp
        automatically matched to d1tfca_
        complexed with 1ba
        
        region a:235-457 [135485]
      21. 2gpp
        automatically matched to d1tfca_
        complexed with 1ba
        
        region b:235-456 [135486]
      22. 2gpv
        automatically matched to d1tfca_
        complexed with oht
        
        region a:235-455 [135494]
      23. 2gpv
        automatically matched to d1tfca_
        complexed with oht
        
        region b:235-455 [135495]
      24. 2gpv
        automatically matched to d1tfca_
        complexed with oht
        
        region c:235-455 [135496]
      25. 1kv6
        complexed with a co-activator peptide
        
        chain a [77546]
        chain b [77547]
      26. 1vjb
        complexed with oht
        
        chain a [108629]
        chain b [108630]
  23. Hepatocyte nuclear factor 4-gamma [81918]
    1. Human (Homo sapiens) [TaxId: 9606] [81919] (1)
      1. 1lv2
        complexed with plm
        
        chain a [78230]
  24. Hepatocyte nuclear factor 4-alpha [109605]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [89146] (1)
      1. 1m7w
        complexed with dao
        
        chain a [84869]
        chain b [84870]
        chain c [84871]
        chain d [84872]
    2. Human (Homo sapiens) [TaxId: 9606] [109987] (1)
      SQ P41235 139-369
      1. 1pzl
        complexed with myr; mutant
        
        chain a [104393]
  25. Orphan nuclear receptor NR5a2 (LRH-1) [89147]
    1. Mouse (Mus musculus) [TaxId: 10090] [89148] (1)
      1. 1pk5
        
        chain a [88139]
        chain b [88140]
  26. Oxysterols receptor LXR-beta [89149]
    1. Human (Homo sapiens) [TaxId: 9606] [89150] (6)
      SQ P55055 219-461
      1. 1pq9
        complexed with 44b, bns
        
        chain a [95004]
        chain b [95005]
        chain c [95006]
        chain d [95007]
      2. 1upv
        complexed with 444
        
        chain a [113398]
      3. 1pq6
        complexed with 965, ioh
        
        chain a [94998]
        chain b [94999]
        chain c [95000]
        chain d [95001]
      4. 1pqc
        complexed with 444
        
        chain a [95009]
        chain b [95010]
        chain c [95011]
        chain d [95012]
      5. 1upw
        complexed with 444
        
        chain a [113399]
      6. 1p8d
        complexed with a co-activator peptide, chains C and D
        complexed with co1
        
        chain a [87941]
        chain b [87942]
  27. Bile acid receptor FXR [101433]
    1. Human (Homo sapiens) [TaxId: 9606] [101434] (5)
      1. 1osh
        complexed with fex
        
        chain a [93496]
      2. 3bej
        automatically matched to d1osha_
        complexed with muf, yt3
        
        region a:245-471 [155186]
      3. 3bej
        automatically matched to d1osha_
        complexed with muf, yt3
        
        region b:245-471 [155187]
      4. 3dct
        automatically matched to d1osha_
        complexed with 064
        
        region a:245-471 [157538]
      5. 3dcu
        automatically matched to d1osha_
        complexed with o62
        
        region a:245-471 [157539]
    2. Rat (Rattus norvegicus) [TaxId: 10116] [101435] (2)
      1. 1osv
        complexed with a co-activator peptide, chains C, D and E
        complexed with chc
        
        chain a [93500]
        chain b [93501]
      2. 1ot7
        complexed with a co-activator peptide, chains C, D and E
        complexed with iu5, iu6
        
        chain a [93505]
        chain b [93506]
  28. Ecdysone receptor [101436]
    1. Noctuid moth (Heliothis virescens) [TaxId: 7102] [101437] (3)
      1. 2r40
        automatically matched to d1r1kd_
        complexed with 20e, eph, flc, gol, so4
        
        region d:287-529 [151572]
      2. 1r1k
        complexed with eph, p1a
        
        chain d [96819]
      3. 1r20
        complexed with eph, hwg
        
        chain d [96845]
  29. Oxysterols receptor LXR-alpha [109988]
    1. Human (Homo sapiens) [TaxId: 9606] [109989] (1)
      SQ Q13133 207-445
      1. 1uhl
        complexed with 444, mei
        
        chain b [107850]
    2. Mouse (Mus musculus) [TaxId: 10090] [158810] (4)
      SQ Q9Z0Y9 203-443
      1. 2acl
        complexed with l05, rea
        
        region b:204-443 [144801]
      2. 2acl
        automatically matched to 2ACL B:204-443
        complexed with l05, rea
        
        region d:204-443 [144802]
      3. 2acl
        automatically matched to 2ACL B:204-443
        complexed with l05, rea
        
        region f:204-443 [144803]
      4. 2acl
        automatically matched to 2ACL B:204-443
        complexed with l05, rea
        
        region h:204-443 [144804]
  30. Steroid hormone receptor ERR1 [109990]
    1. Human (Homo sapiens) [TaxId: 9606] [109991] (3)
      SQ P11474 289-516
      1. 3d24
        automatically matched to d1xb7a_
        
        region a:194-420 [157216]
      2. 3d24
        automatically matched to d1xb7a_
        
        region c:194-420 [157217]
      3. 1xb7
        complexed with iod; mutant
        
        chain a [109537]
  31. Retinoic acid receptor beta (RAR-beta) [117011]
    1. Mouse (Mus musculus) [TaxId: 10090] [117012] (1)
      SQ P22605 209-453
      1. 1xdk
        complexed with rea
        
        chain b [115165]
        chain f [115167]
    2. Human (Homo sapiens) [TaxId: 9606] [117013] (1)
      SQ P10826 182-416
      1. 1xap
        complexed with ttb
        
        chain a [115038]
  32. Orphan nuclear receptor NR1I3 (CAR) [117014]
    1. Mouse (Mus musculus) [TaxId: 10090] [117015] (2)
      SQ O35627 109-358
      1. 1xnx
        complexed with ate
        
        chain a [115667]
        chain b [115668]
      2. 1xls
        complexed with rea, tcd; mutant
        
        chain e [115451]
        chain f [115452]
        chain g [115453]
        chain h [115454]
    2. Human (Homo sapiens) [TaxId: 9606] [117016] (2)
      SQ Q14994 103-352
      1. 1xvp
        complexed with cid, f15
        
        chain b [116091]
        chain d [116093]
      2. 1xv9
        complexed with ci2, f15
        
        chain b [116081]
        chain d [116083]
  33. Orphan nuclear receptor NR4A1 [158811]
    1. Human (Homo sapiens) [TaxId: 9606] [158812] (4)
      SQ P22736 363-595
      1. 2qw4
        
        region a:32-264 [151397]
      2. 2qw4
        automatically matched to 2QW4 A:32-264
        
        region b:32-264 [151398]
      3. 2qw4
        automatically matched to 2QW4 A:32-264
        
        region c:32-264 [151399]
      4. 2qw4
        automatically matched to 2QW4 A:32-264
        
        region d:32-264 [151400]